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PubMed:16377754 JSONTXT 52 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-107 Sentence denotes A defect in exodegradative pathways provides insight into endodegradation of heparan and dermatan sulfates.
T1 0-107 Sentence denotes A defect in exodegradative pathways provides insight into endodegradation of heparan and dermatan sulfates.
T1 0-107 Sentence denotes A defect in exodegradative pathways provides insight into endodegradation of heparan and dermatan sulfates.
TextSentencer_T2 108-195 Sentence denotes Within cells, dermatan sulfate (DS) and heparan sulfate (HS) are degraded in two steps.
T2 108-195 Sentence denotes Within cells, dermatan sulfate (DS) and heparan sulfate (HS) are degraded in two steps.
T2 108-195 Sentence denotes Within cells, dermatan sulfate (DS) and heparan sulfate (HS) are degraded in two steps.
TextSentencer_T3 196-391 Sentence denotes The initial endohydrolysis of these polysaccharides is followed by the sequential action of lysosomal exoenzymes to reduce the resulting oligosaccharides to monosaccharides and inorganic sulfate.
T3 196-391 Sentence denotes The initial endohydrolysis of these polysaccharides is followed by the sequential action of lysosomal exoenzymes to reduce the resulting oligosaccharides to monosaccharides and inorganic sulfate.
T3 196-391 Sentence denotes The initial endohydrolysis of these polysaccharides is followed by the sequential action of lysosomal exoenzymes to reduce the resulting oligosaccharides to monosaccharides and inorganic sulfate.
TextSentencer_T4 392-528 Sentence denotes Mucopolysaccharidosis (MPS) type II is a lysosomal storage disorder caused by a deficiency of the exoenzyme iduronate-2-sulfatase (I2S).
T4 392-528 Sentence denotes Mucopolysaccharidosis (MPS) type II is a lysosomal storage disorder caused by a deficiency of the exoenzyme iduronate-2-sulfatase (I2S).
T4 392-528 Sentence denotes Mucopolysaccharidosis (MPS) type II is a lysosomal storage disorder caused by a deficiency of the exoenzyme iduronate-2-sulfatase (I2S).
TextSentencer_T5 529-680 Sentence denotes Consequently, partially degraded fragments of DS and HS have been shown to accumulate in the lysosomes of affected cells and are excreted in the urine.
T5 529-680 Sentence denotes Consequently, partially degraded fragments of DS and HS have been shown to accumulate in the lysosomes of affected cells and are excreted in the urine.
T5 529-680 Sentence denotes Consequently, partially degraded fragments of DS and HS have been shown to accumulate in the lysosomes of affected cells and are excreted in the urine.
TextSentencer_T6 681-892 Sentence denotes Di- to hexadecasaccharides, isolated from the urine of a MPS II patient using anion exchange and gel filtration chromatography, were identified using electrospray ionization-tandem mass spectrometry (ESI-MS/MS).
T6 681-892 Sentence denotes Di- to hexadecasaccharides, isolated from the urine of a MPS II patient using anion exchange and gel filtration chromatography, were identified using electrospray ionization-tandem mass spectrometry (ESI-MS/MS).
T6 681-892 Sentence denotes Di- to hexadecasaccharides, isolated from the urine of a MPS II patient using anion exchange and gel filtration chromatography, were identified using electrospray ionization-tandem mass spectrometry (ESI-MS/MS).
TextSentencer_T7 893-1020 Sentence denotes These oligosaccharides were shown to have non-reducing terminal iduronate-2-sulfate residues by digestion with recombinant I2S.
T7 893-1020 Sentence denotes These oligosaccharides were shown to have non-reducing terminal iduronate-2-sulfate residues by digestion with recombinant I2S.
T7 893-1020 Sentence denotes These oligosaccharides were shown to have non-reducing terminal iduronate-2-sulfate residues by digestion with recombinant I2S.
TextSentencer_T8 1021-1183 Sentence denotes A pattern of growing oligosaccharide chains composed of alternating uronic acid and N-acetylhexosamine residues was identified and suggested to originate from DS.
T8 1021-1183 Sentence denotes A pattern of growing oligosaccharide chains composed of alternating uronic acid and N-acetylhexosamine residues was identified and suggested to originate from DS.
T8 1021-1183 Sentence denotes A pattern of growing oligosaccharide chains composed of alternating uronic acid and N-acetylhexosamine residues was identified and suggested to originate from DS.
TextSentencer_T9 1184-1430 Sentence denotes A series of oligosaccharides consisting of hexosamine/N-acetylhexosamine alternating with uronic acid residues was also identified and on the basis of the presence of unacetylated hexosamine; these oligosaccharides are proposed to derive from HS.
T9 1184-1430 Sentence denotes A series of oligosaccharides consisting of hexosamine/N-acetylhexosamine alternating with uronic acid residues was also identified and on the basis of the presence of unacetylated hexosamine; these oligosaccharides are proposed to derive from HS.
T9 1184-1430 Sentence denotes A series of oligosaccharides consisting of hexosamine/N-acetylhexosamine alternating with uronic acid residues was also identified and on the basis of the presence of unacetylated hexosamine; these oligosaccharides are proposed to derive from HS.
TextSentencer_T10 1431-1601 Sentence denotes The presence of both odd and even-length oligosaccharides suggests both endo-beta-glucuronidase and endo-N-acetylhexosaminidase activities toward both glycosaminoglycans.
T10 1431-1601 Sentence denotes The presence of both odd and even-length oligosaccharides suggests both endo-beta-glucuronidase and endo-N-acetylhexosaminidase activities toward both glycosaminoglycans.
T10 1431-1601 Sentence denotes The presence of both odd and even-length oligosaccharides suggests both endo-beta-glucuronidase and endo-N-acetylhexosaminidase activities toward both glycosaminoglycans.
TextSentencer_T11 1602-1869 Sentence denotes Furthermore, the putative HS oligosaccharide structures identified indicate that heparanase activities are directed toward regions of both low and high sulfation, while the N-acetylhexosaminidase activity acted only in regions of low sulfation in this polysaccharide.
T11 1602-1869 Sentence denotes Furthermore, the putative HS oligosaccharide structures identified indicate that heparanase activities are directed toward regions of both low and high sulfation, while the N-acetylhexosaminidase activity acted only in regions of low sulfation in this polysaccharide.
T11 1602-1869 Sentence denotes Furthermore, the putative HS oligosaccharide structures identified indicate that heparanase activities are directed toward regions of both low and high sulfation, while the N-acetylhexosaminidase activity acted only in regions of low sulfation in this polysaccharide.