| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-73 |
Sentence |
denotes |
Serum hyaluronidase aberrations in metabolic and morphogenetic disorders. |
| TextSentencer_T1 |
0-73 |
Sentence |
denotes |
Serum hyaluronidase aberrations in metabolic and morphogenetic disorders. |
| T1 |
0-73 |
Sentence |
denotes |
Serum hyaluronidase aberrations in metabolic and morphogenetic disorders. |
| TextSentencer_T2 |
74-188 |
Sentence |
denotes |
Hyaluronidases are endo-glycosidases that degrade both hyaluronan (hyaluronic acid) (HA) and chondroitin sulfates. |
| TextSentencer_T2 |
74-188 |
Sentence |
denotes |
Hyaluronidases are endo-glycosidases that degrade both hyaluronan (hyaluronic acid) (HA) and chondroitin sulfates. |
| T2 |
74-188 |
Sentence |
denotes |
Hyaluronidases are endo-glycosidases that degrade both hyaluronan (hyaluronic acid) (HA) and chondroitin sulfates. |
| TextSentencer_T3 |
189-326 |
Sentence |
denotes |
Deficiency of hyaluronidase activity has been predicted to result in a phenotype similar to that observed in mucopolysaccharidosis (MPS). |
| TextSentencer_T3 |
189-326 |
Sentence |
denotes |
Deficiency of hyaluronidase activity has been predicted to result in a phenotype similar to that observed in mucopolysaccharidosis (MPS). |
| T3 |
189-326 |
Sentence |
denotes |
Deficiency of hyaluronidase activity has been predicted to result in a phenotype similar to that observed in mucopolysaccharidosis (MPS). |
| TextSentencer_T4 |
327-566 |
Sentence |
denotes |
In the present study, we surveyed a variety of patients with phenotypes similar to those observed in MPS, but without significant mucopolysacchariduria to determine if some are based on aberrations in serum hyaluronidase (Hyal-1) activity. |
| TextSentencer_T4 |
327-566 |
Sentence |
denotes |
In the present study, we surveyed a variety of patients with phenotypes similar to those observed in MPS, but without significant mucopolysacchariduria to determine if some are based on aberrations in serum hyaluronidase (Hyal-1) activity. |
| T4 |
327-566 |
Sentence |
denotes |
In the present study, we surveyed a variety of patients with phenotypes similar to those observed in MPS, but without significant mucopolysacchariduria to determine if some are based on aberrations in serum hyaluronidase (Hyal-1) activity. |
| TextSentencer_T5 |
567-704 |
Sentence |
denotes |
The study included patients with well-characterized dysmorphic disorders occurring on genetic basis, as well as those of unkown etiology. |
| TextSentencer_T5 |
567-704 |
Sentence |
denotes |
The study included patients with well-characterized dysmorphic disorders occurring on genetic basis, as well as those of unkown etiology. |
| T5 |
567-704 |
Sentence |
denotes |
The study included patients with well-characterized dysmorphic disorders occurring on genetic basis, as well as those of unkown etiology. |
| TextSentencer_T6 |
705-823 |
Sentence |
denotes |
The purpose of the study was to establish how wide spread were abnormalities in levels of circulating Hyal-1 activity. |
| TextSentencer_T6 |
705-823 |
Sentence |
denotes |
The purpose of the study was to establish how wide spread were abnormalities in levels of circulating Hyal-1 activity. |
| T6 |
705-823 |
Sentence |
denotes |
The purpose of the study was to establish how wide spread were abnormalities in levels of circulating Hyal-1 activity. |
| TextSentencer_T7 |
824-930 |
Sentence |
denotes |
A simple and sensitive semi-quantitative zymographic procedure was used for the determination of activity. |
| TextSentencer_T7 |
824-930 |
Sentence |
denotes |
A simple and sensitive semi-quantitative zymographic procedure was used for the determination of activity. |
| T7 |
824-930 |
Sentence |
denotes |
A simple and sensitive semi-quantitative zymographic procedure was used for the determination of activity. |
| TextSentencer_T8 |
931-1135 |
Sentence |
denotes |
Levels of both beta-N-acetylglucosaminidase and beta-glucuronidase whose activities contribute to the total breakdown of hyaluronan (HA) were also measured, as well as the concentration of circulating HA. |
| TextSentencer_T8 |
931-1135 |
Sentence |
denotes |
Levels of both beta-N-acetylglucosaminidase and beta-glucuronidase whose activities contribute to the total breakdown of hyaluronan (HA) were also measured, as well as the concentration of circulating HA. |
| T8 |
931-1135 |
Sentence |
denotes |
Levels of both beta-N-acetylglucosaminidase and beta-glucuronidase whose activities contribute to the total breakdown of hyaluronan (HA) were also measured, as well as the concentration of circulating HA. |
| TextSentencer_T9 |
1136-1349 |
Sentence |
denotes |
Among 48 patients with bone or connective tissue abnormalities, low levels of Hyal-1 activity were found in six patients compared to levels in 100 healthy donors (2.0-3.2 units/microL vs 6(+/- 1 SE) units/microL). |
| TextSentencer_T9 |
1136-1349 |
Sentence |
denotes |
Among 48 patients with bone or connective tissue abnormalities, low levels of Hyal-1 activity were found in six patients compared to levels in 100 healthy donors (2.0-3.2 units/microL vs 6(+/- 1 SE) units/microL). |
| T9 |
1136-1349 |
Sentence |
denotes |
Among 48 patients with bone or connective tissue abnormalities, low levels of Hyal-1 activity were found in six patients compared to levels in 100 healthy donors (2.0-3.2 units/microL vs 6(+/- 1 SE) units/microL). |
| TextSentencer_T10 |
1350-1652 |
Sentence |
denotes |
These six patients exhibited a wide spectrum of clinical abnormalities, in particular shortened extremities: they included three patients with unknown causes of clinical symptoms, one patient with Sanfilippo disease, one of the seven patients with achondroplasia, and one with hypophosphotemic rickets. |
| TextSentencer_T10 |
1350-1652 |
Sentence |
denotes |
These six patients exhibited a wide spectrum of clinical abnormalities, in particular shortened extremities: they included three patients with unknown causes of clinical symptoms, one patient with Sanfilippo disease, one of the seven patients with achondroplasia, and one with hypophosphotemic rickets. |
| T10 |
1350-1652 |
Sentence |
denotes |
These six patients exhibited a wide spectrum of clinical abnormalities, in particular shortened extremities: they included three patients with unknown causes of clinical symptoms, one patient with Sanfilippo disease, one of the seven patients with achondroplasia, and one with hypophosphotemic rickets. |
| TextSentencer_T11 |
1653-1861 |
Sentence |
denotes |
Normal levels of serum Hyal-1 activities were found in patients with Morquio disease, GM1 gangliosidosis, I cell-disease, 6 of the 7 patients with achondroplasia, Marfan's-syndrome and Ehlers-Danlos syndrome. |
| TextSentencer_T11 |
1653-1861 |
Sentence |
denotes |
Normal levels of serum Hyal-1 activities were found in patients with Morquio disease, GM1 gangliosidosis, I cell-disease, 6 of the 7 patients with achondroplasia, Marfan's-syndrome and Ehlers-Danlos syndrome. |
| T11 |
1653-1861 |
Sentence |
denotes |
Normal levels of serum Hyal-1 activities were found in patients with Morquio disease, GM1 gangliosidosis, I cell-disease, 6 of the 7 patients with achondroplasia, Marfan's-syndrome and Ehlers-Danlos syndrome. |
| TextSentencer_T12 |
1862-1910 |
Sentence |
denotes |
No patient totally lacked serum Hyal-1 activity. |
| TextSentencer_T12 |
1862-1910 |
Sentence |
denotes |
No patient totally lacked serum Hyal-1 activity. |
| T12 |
1862-1910 |
Sentence |
denotes |
No patient totally lacked serum Hyal-1 activity. |
| TextSentencer_T13 |
1911-1996 |
Sentence |
denotes |
Serum HA concentration was elevated in patients with Sanfilippo A and I-cell disease. |
| TextSentencer_T13 |
1911-1996 |
Sentence |
denotes |
Serum HA concentration was elevated in patients with Sanfilippo A and I-cell disease. |
| T13 |
1911-1996 |
Sentence |
denotes |
Serum HA concentration was elevated in patients with Sanfilippo A and I-cell disease. |
| TextSentencer_T14 |
1997-2132 |
Sentence |
denotes |
Determination of serum and leukocyte Hyal-1 and serum HA may be useful to evaluate patients with metabolic and morphogenetic disorders. |
| TextSentencer_T14 |
1997-2132 |
Sentence |
denotes |
Determination of serum and leukocyte Hyal-1 and serum HA may be useful to evaluate patients with metabolic and morphogenetic disorders. |
| T14 |
1997-2132 |
Sentence |
denotes |
Determination of serum and leukocyte Hyal-1 and serum HA may be useful to evaluate patients with metabolic and morphogenetic disorders. |