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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-92 Sentence denotes Differential selectivity of hyaluronidase inhibitors toward acidic and basic hyaluronidases.
T1 0-92 Sentence denotes Differential selectivity of hyaluronidase inhibitors toward acidic and basic hyaluronidases.
T1 0-92 Sentence denotes Differential selectivity of hyaluronidase inhibitors toward acidic and basic hyaluronidases.
TextSentencer_T2 93-263 Sentence denotes Hyaluronidase (HAase), a class of enzymes which degrade hyaluronic acid (HA), are involved in the spread of infections/toxins, ovum fertilization, and cancer progression.
T2 93-263 Sentence denotes Hyaluronidase (HAase), a class of enzymes which degrade hyaluronic acid (HA), are involved in the spread of infections/toxins, ovum fertilization, and cancer progression.
T2 93-263 Sentence denotes Hyaluronidase (HAase), a class of enzymes which degrade hyaluronic acid (HA), are involved in the spread of infections/toxins, ovum fertilization, and cancer progression.
TextSentencer_T3 264-322 Sentence denotes Thus, HAase inhibitors may have use in disease treatments.
T3 264-322 Sentence denotes Thus, HAase inhibitors may have use in disease treatments.
T3 264-322 Sentence denotes Thus, HAase inhibitors may have use in disease treatments.
TextSentencer_T4 323-418 Sentence denotes We evaluated 21 HAase inhibitors against HYAL-1, testicular, honeybee, and Streptomyces HAases.
T4 323-418 Sentence denotes We evaluated 21 HAase inhibitors against HYAL-1, testicular, honeybee, and Streptomyces HAases.
T4 323-418 Sentence denotes We evaluated 21 HAase inhibitors against HYAL-1, testicular, honeybee, and Streptomyces HAases.
TextSentencer_T5 419-634 Sentence denotes Among these inhibitors, polymers of poly (styrene-4-sulfonate) (PSS) (i.e., molecular weight 1400-990,000 or PSS 1400-PSS 990,000) and O-sulfated HA (sHA) derivatives (sHA2.0, 2.5, and 2.75) were the most effective.
T5 419-634 Sentence denotes Among these inhibitors, polymers of poly (styrene-4-sulfonate) (PSS) (i.e., molecular weight 1400-990,000 or PSS 1400-PSS 990,000) and O-sulfated HA (sHA) derivatives (sHA2.0, 2.5, and 2.75) were the most effective.
T5 419-634 Sentence denotes Among these inhibitors, polymers of poly (styrene-4-sulfonate) (PSS) (i.e., molecular weight 1400-990,000 or PSS 1400-PSS 990,000) and O-sulfated HA (sHA) derivatives (sHA2.0, 2.5, and 2.75) were the most effective.
TextSentencer_T6 635-825 Sentence denotes HYAL-1 and bee HAases were the most sensitive, followed by testicular HAase; Streptomyces HAase was resistant to all inhibitors, except PSS 990,000 and VERSA-TL 502 (i.e., PSS 10(6) dalton).
T6 635-825 Sentence denotes HYAL-1 and bee HAases were the most sensitive, followed by testicular HAase; Streptomyces HAase was resistant to all inhibitors, except PSS 990,000 and VERSA-TL 502 (i.e., PSS 10(6) dalton).
T6 635-825 Sentence denotes HYAL-1 and bee HAases were the most sensitive, followed by testicular HAase; Streptomyces HAase was resistant to all inhibitors, except PSS 990,000 and VERSA-TL 502 (i.e., PSS 10(6) dalton).
TextSentencer_T7 826-917 Sentence denotes The length of the PSS polymer determined their potency (e.g., IC50 for HYAL-1, PSS 990,000:
T7 826-917 Sentence denotes The length of the PSS polymer determined their potency (e.g., IC50 for HYAL-1, PSS 990,000:
T7 826-917 Sentence denotes The length of the PSS polymer determined their potency (e.g., IC50 for HYAL-1, PSS 990,000:
TextSentencer_T8 918-995 Sentence denotes 0.0096 microM; PSS 210 no inhibition; IC50 for testicular HAase, PSS 990,000:
T8 918-995 Sentence denotes 0.0096 microM; PSS 210 no inhibition; IC50 for testicular HAase, PSS 990,000:
T8 918-995 Sentence denotes 0.0096 microM; PSS 210 no inhibition; IC50 for testicular HAase, PSS 990,000:
TextSentencer_T9 996-1033 Sentence denotes 0.042 microM; PSS 210 no inhibition).
T9 996-1033 Sentence denotes 0.042 microM; PSS 210 no inhibition).
T9 996-1033 Sentence denotes 0.042 microM; PSS 210 no inhibition).
TextSentencer_T10 1034-1199 Sentence denotes The presence, but not the number, of sulfate groups on the sHA molecule determined its potency (e.g., IC50 for HYAL-1: sHA2.0, 0.019 microM; sHA2.75, 0.0083 microM).
T10 1034-1199 Sentence denotes The presence, but not the number, of sulfate groups on the sHA molecule determined its potency (e.g., IC50 for HYAL-1: sHA2.0, 0.019 microM; sHA2.75, 0.0083 microM).
T10 1034-1199 Sentence denotes The presence, but not the number, of sulfate groups on the sHA molecule determined its potency (e.g., IC50 for HYAL-1: sHA2.0, 0.019 microM; sHA2.75, 0.0083 microM).
TextSentencer_T11 1200-1342 Sentence denotes Other known HAase inhibitors, such as gossypol, sodium-aurothiomalate, 1-tetradecane sulfonic acid, and glycerrhizic acid, were not effective.
T11 1200-1342 Sentence denotes Other known HAase inhibitors, such as gossypol, sodium-aurothiomalate, 1-tetradecane sulfonic acid, and glycerrhizic acid, were not effective.
T11 1200-1342 Sentence denotes Other known HAase inhibitors, such as gossypol, sodium-aurothiomalate, 1-tetradecane sulfonic acid, and glycerrhizic acid, were not effective.
TextSentencer_T12 1343-1534 Sentence denotes Both PSS and sHA inhibited HAases by a mixed inhibition mechanism (i.e., competitive + uncompetitive) and were 5- to 17-fold better as uncompetitive inhibitors than as competitive inhibitors.
T12 1343-1534 Sentence denotes Both PSS and sHA inhibited HAases by a mixed inhibition mechanism (i.e., competitive + uncompetitive) and were 5- to 17-fold better as uncompetitive inhibitors than as competitive inhibitors.
T12 1343-1534 Sentence denotes Both PSS and sHA inhibited HAases by a mixed inhibition mechanism (i.e., competitive + uncompetitive) and were 5- to 17-fold better as uncompetitive inhibitors than as competitive inhibitors.
TextSentencer_T13 1535-1743 Sentence denotes These results demonstrate that HAase inhibitors show selectivity toward the different types of HAases, which could be exploited to inhibit specific HAases involved in a variety of pathophysiologic conditions.
T13 1535-1743 Sentence denotes These results demonstrate that HAase inhibitors show selectivity toward the different types of HAases, which could be exploited to inhibit specific HAases involved in a variety of pathophysiologic conditions.
T13 1535-1743 Sentence denotes These results demonstrate that HAase inhibitors show selectivity toward the different types of HAases, which could be exploited to inhibit specific HAases involved in a variety of pathophysiologic conditions.