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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-59 Sentence denotes Polysialic acid facilitates tumor invasion by glioma cells.
T1 0-59 Sentence denotes Polysialic acid facilitates tumor invasion by glioma cells.
TextSentencer_T2 60-213 Sentence denotes Polysialic acid (PSA) is thought to attenuate neural cell adhesion molecule (NCAM) adhesion, thereby facilitating neural cell migration and regeneration.
T2 60-213 Sentence denotes Polysialic acid (PSA) is thought to attenuate neural cell adhesion molecule (NCAM) adhesion, thereby facilitating neural cell migration and regeneration.
TextSentencer_T3 214-470 Sentence denotes Although the expression of PSA has been shown to correlate with the progression of certain tumors such as small cell lung carcinoma, there have been no studies to determine the roles of PSA in gliomas, the most common type of primary brain tumor in humans.
T3 214-470 Sentence denotes Although the expression of PSA has been shown to correlate with the progression of certain tumors such as small cell lung carcinoma, there have been no studies to determine the roles of PSA in gliomas, the most common type of primary brain tumor in humans.
TextSentencer_T4 471-625 Sentence denotes In this study, we first revealed that among patients with glioma, PSA was detected more frequently in diffuse astrocytoma cells, which spread extensively.
T4 471-625 Sentence denotes In this study, we first revealed that among patients with glioma, PSA was detected more frequently in diffuse astrocytoma cells, which spread extensively.
TextSentencer_T5 626-763 Sentence denotes To determine directly the role of PSA in glioma cell invasion, we transfected C6 glioma cells with polysialyltransferases to express PSA.
T5 626-763 Sentence denotes To determine directly the role of PSA in glioma cell invasion, we transfected C6 glioma cells with polysialyltransferases to express PSA.
TextSentencer_T6 764-914 Sentence denotes In those transfected cells, PSA is attached mainly to NCAM-140, whereas the mock-transfected C6 cells express equivalent amounts of PSA-free NCAM-140.
T6 764-914 Sentence denotes In those transfected cells, PSA is attached mainly to NCAM-140, whereas the mock-transfected C6 cells express equivalent amounts of PSA-free NCAM-140.
TextSentencer_T7 915-1018 Sentence denotes Both PSA negative and positive C6 cell lines exhibited almost identical growth rates measured in vitro.
T7 915-1018 Sentence denotes Both PSA negative and positive C6 cell lines exhibited almost identical growth rates measured in vitro.
TextSentencer_T8 1019-1192 Sentence denotes However, PSA positive C6 cells exhibited increased invasion to the corpus callosum, where the mock-transfected C6 glioma cells rarely invaded when inoculated into the brain.
T8 1019-1192 Sentence denotes However, PSA positive C6 cells exhibited increased invasion to the corpus callosum, where the mock-transfected C6 glioma cells rarely invaded when inoculated into the brain.
TextSentencer_T9 1193-1333 Sentence denotes By contrast, the invasion to the corpus callosum by both the mock-transfected and PSA positive C6 cells was observed in NCAM-deficient mice.
T9 1193-1333 Sentence denotes By contrast, the invasion to the corpus callosum by both the mock-transfected and PSA positive C6 cells was observed in NCAM-deficient mice.
TextSentencer_T10 1334-1513 Sentence denotes These results combined indicate that PSA facilitates tumor invasion of glioma in the brain, and that NCAM-NCAM interaction is likely attenuated in the PSA-mediated tumor invasion.
T10 1334-1513 Sentence denotes These results combined indicate that PSA facilitates tumor invasion of glioma in the brain, and that NCAM-NCAM interaction is likely attenuated in the PSA-mediated tumor invasion.