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PubMed:15821891 JSONTXT 6 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-136 Sentence denotes Immunogenic properties of a chimeric plant virus expressing a hepatitis C virus (HCV)-derived epitope: new prospects for an HCV vaccine.
T1 0-136 Sentence denotes Immunogenic properties of a chimeric plant virus expressing a hepatitis C virus (HCV)-derived epitope: new prospects for an HCV vaccine.
TextSentencer_T2 137-263 Sentence denotes A vaccine against Hepatitis C virus (HCV) is urgently needed due to the unsatisfactory clinical response to current therapies.
T2 137-263 Sentence denotes A vaccine against Hepatitis C virus (HCV) is urgently needed due to the unsatisfactory clinical response to current therapies.
TextSentencer_T3 264-498 Sentence denotes We evaluated the immunological properties of a chimeric Cucumber mosaic virus (CMV), a plant virus engineered to express on its surface a synthetic peptide derived from many HVR1 sequences of the HCV envelope protein E2 (R9 mimotope).
T3 264-498 Sentence denotes We evaluated the immunological properties of a chimeric Cucumber mosaic virus (CMV), a plant virus engineered to express on its surface a synthetic peptide derived from many HVR1 sequences of the HCV envelope protein E2 (R9 mimotope).
TextSentencer_T4 499-593 Sentence denotes Evidence was obtained that the chimeric R9-CMV elicits a specific humoral response in rabbits.
T4 499-593 Sentence denotes Evidence was obtained that the chimeric R9-CMV elicits a specific humoral response in rabbits.
TextSentencer_T5 594-863 Sentence denotes Furthermore, in patients with chronic HCV infection, purified preparations of R9-CMV down-modulated the lymphocyte surface density of CD3 and CD8, and induced a significant release of interferon (IFN)-gamma, interleukin (IL)-12 p70 and IL-15 by lymphomonocyte cultures.
T5 594-863 Sentence denotes Furthermore, in patients with chronic HCV infection, purified preparations of R9-CMV down-modulated the lymphocyte surface density of CD3 and CD8, and induced a significant release of interferon (IFN)-gamma, interleukin (IL)-12 p70 and IL-15 by lymphomonocyte cultures.
TextSentencer_T6 864-1022 Sentence denotes Finally, an R9 mimotope-specific CD8 T-cell response, as assessed by intracellular IFN-gamma production, was achieved in the majority of the patients studied.
T6 864-1022 Sentence denotes Finally, an R9 mimotope-specific CD8 T-cell response, as assessed by intracellular IFN-gamma production, was achieved in the majority of the patients studied.
TextSentencer_T7 1023-1121 Sentence denotes Our results open up new prospects for the development of effective vaccines against HCV infection.
T7 1023-1121 Sentence denotes Our results open up new prospects for the development of effective vaccines against HCV infection.
TextSentencer_T8 1122-1220 Sentence denotes Moreover, the wide edible host range of CMV makes the production of an edible vaccine conceivable.
T8 1122-1220 Sentence denotes Moreover, the wide edible host range of CMV makes the production of an edible vaccine conceivable.