> top > projects > sentences > docs > PubMed:15684415 > annotations
sentences Home  

PubMed:15684415 JSONTXT 41 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-149 Sentence denotes A novel pineal-specific product of the oligopeptide transporter PepT1 gene: circadian expression mediated by cAMP activation of an intronic promoter.
T1 0-149 Sentence denotes A novel pineal-specific product of the oligopeptide transporter PepT1 gene: circadian expression mediated by cAMP activation of an intronic promoter.
TextSentencer_T2 150-452 Sentence denotes The oligopeptide transporter 1, PepT1, is a member of the Slc15 family of 12 membrane-spanning domain transporters; PepT1 has proton/peptide cotransport activity and is selectively expressed in intestinal epithelial cells, where it is responsible for the nutritional absorption of di- and tri-peptides.
T2 150-452 Sentence denotes The oligopeptide transporter 1, PepT1, is a member of the Slc15 family of 12 membrane-spanning domain transporters; PepT1 has proton/peptide cotransport activity and is selectively expressed in intestinal epithelial cells, where it is responsible for the nutritional absorption of di- and tri-peptides.
TextSentencer_T3 453-546 Sentence denotes Here, a novel PepT1 gene product has been identified in the rat pineal gland, termed pgPepT1.
T3 453-546 Sentence denotes Here, a novel PepT1 gene product has been identified in the rat pineal gland, termed pgPepT1.
TextSentencer_T4 547-706 Sentence denotes It encodes a 150-amino acid protein encompassing the C-terminal 3 membrane-spanning domains of intestinal PepT1 protein, with 3 additional N-terminal residues.
T4 547-706 Sentence denotes It encodes a 150-amino acid protein encompassing the C-terminal 3 membrane-spanning domains of intestinal PepT1 protein, with 3 additional N-terminal residues.
TextSentencer_T5 707-972 Sentence denotes Expression of pgPepT1 appears to be restricted to the pineal gland and follows a marked circadian pattern with >100-fold higher levels of mRNA occurring at night; this is accompanied by an accumulation of membrane-associated pgPepT1 protein ( approximately 16 kDa).
T5 707-972 Sentence denotes Expression of pgPepT1 appears to be restricted to the pineal gland and follows a marked circadian pattern with >100-fold higher levels of mRNA occurring at night; this is accompanied by an accumulation of membrane-associated pgPepT1 protein ( approximately 16 kDa).
TextSentencer_T6 973-1098 Sentence denotes The daily rhythm in pgPepT1 mRNA is regulated by the well described neural pathway that controls pineal melatonin production.
T6 973-1098 Sentence denotes The daily rhythm in pgPepT1 mRNA is regulated by the well described neural pathway that controls pineal melatonin production.
TextSentencer_T7 1099-1317 Sentence denotes This includes the retina, the circadian clock in the suprachiasmatic nucleus, central structures, and projections from the superior cervical ganglia; activation of this pathway results in the release of norepinephrine.
T7 1099-1317 Sentence denotes This includes the retina, the circadian clock in the suprachiasmatic nucleus, central structures, and projections from the superior cervical ganglia; activation of this pathway results in the release of norepinephrine.
TextSentencer_T8 1318-1637 Sentence denotes Here it was found that pgPepT1 expression is mediated by a norepinephrine-->cyclic AMP mechanism that activates an alternative promoter located in intron 20 of the gene. pgPepT1 protein was found to have transporter-modulator activity; it could contribute to circadian changes in pineal function through this mechanism.
T8 1318-1637 Sentence denotes Here it was found that pgPepT1 expression is mediated by a norepinephrine-->cyclic AMP mechanism that activates an alternative promoter located in intron 20 of the gene. pgPepT1 protein was found to have transporter-modulator activity; it could contribute to circadian changes in pineal function through this mechanism.