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PubMed:1560002 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-124 Sentence denotes The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA.
T1 0-124 Sentence denotes The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA.
T2 125-284 Sentence denotes The promoter of the major histocompatibility class II gene DRA contains an octamer element (ATTTGCAT) that is required for efficient DRA expression in B cells.
T2 125-284 Sentence denotes The promoter of the major histocompatibility class II gene DRA contains an octamer element (ATTTGCAT) that is required for efficient DRA expression in B cells.
T3 285-346 Sentence denotes Several DNA-binding proteins are known to bind this sequence.
T3 285-346 Sentence denotes Several DNA-binding proteins are known to bind this sequence.
T4 347-425 Sentence denotes The best characterized are the B cell-specific OTF-2 and the ubiquitous OTF-1.
T4 347-425 Sentence denotes The best characterized are the B cell-specific OTF-2 and the ubiquitous OTF-1.
T5 426-508 Sentence denotes This report directly demonstrates that OTF-2 but not OTF-1 regulates the DRA gene.
T5 426-508 Sentence denotes This report directly demonstrates that OTF-2 but not OTF-1 regulates the DRA gene.
T6 509-687 Sentence denotes In vitro transcription analysis using protein fractions enriched for the octamer-binding protein OTF-2 demonstrate a positive functional role for OTF-2 in DRA gene transcription.
T6 509-687 Sentence denotes In vitro transcription analysis using protein fractions enriched for the octamer-binding protein OTF-2 demonstrate a positive functional role for OTF-2 in DRA gene transcription.
T7 688-840 Sentence denotes In contrast, OTF-1-enriched protein fractions did not affect DRA gene transcription although it functionally enhanced the transcription of another gene.
T7 688-840 Sentence denotes In contrast, OTF-1-enriched protein fractions did not affect DRA gene transcription although it functionally enhanced the transcription of another gene.
T8 841-965 Sentence denotes Recombinant OTF-2 protein produced by in vitro transcription/translation could also enhance DRA gene transcription in vitro.
T8 841-965 Sentence denotes Recombinant OTF-2 protein produced by in vitro transcription/translation could also enhance DRA gene transcription in vitro.
T9 966-1180 Sentence denotes In vivo transient transfection studies utilizing an OTF-2 expression vector resulted in similar findings: that OTF-2 protein enhanced DRA gene transcription, and that this effect requires an intact octamer element.
T9 966-1180 Sentence denotes In vivo transient transfection studies utilizing an OTF-2 expression vector resulted in similar findings: that OTF-2 protein enhanced DRA gene transcription, and that this effect requires an intact octamer element.
T10 1181-1335 Sentence denotes Together these results constitute the first direct evidence of a positive role for the lymphoid-specific octamer-binding factor in DRA gene transcription.
T10 1181-1335 Sentence denotes Together these results constitute the first direct evidence of a positive role for the lymphoid-specific octamer-binding factor in DRA gene transcription.