| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-97 |
Sentence |
denotes |
A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. |
| T2 |
98-299 |
Sentence |
denotes |
Among the members of the major facilitator superfamily of Saccharomyces cerevisiae, we identified genes involved in the transport into vacuoles of the basic amino acids histidine, lysine, and arginine. |
| T3 |
300-532 |
Sentence |
denotes |
ATP-dependent uptake of histidine and lysine by isolated vacuolar membrane vesicles was impaired in YMR088c, a vacuolar basic amino acid transporter 1 (VBA1)-deleted strain, whereas uptake of tyrosine or calcium was little affected. |
| T4 |
533-775 |
Sentence |
denotes |
This defect in histidine and lysine uptake was complemented fully by introducing the VBA1 gene and partially by a gene encoding Vba1p fused with green fluorescent protein, which was determined to localize exclusively to the vacuolar membrane. |
| T5 |
776-930 |
Sentence |
denotes |
A defect in the uptake of histidine, lysine, or arginine was also observed in the vacuolar membrane vesicles of mutants YBR293w (VBA2) and YCL069w (VBA3). |
| T6 |
931-1072 |
Sentence |
denotes |
These three VBA genes are closely related phylogenetically and constitute a new family of basic amino acid transporters in the yeast vacuole. |
