> top > projects > sentences > docs > PubMed:15314219 > annotations
sentences Home  

PubMed:15314219 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-95 Sentence denotes Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling.
T1 0-95 Sentence denotes Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling.
TextSentencer_T2 96-242 Sentence denotes Prostate cancer is the most common solid tumor in men, and it shares with all cancers the hallmark of elevated, nonhomeostatic cell proliferation.
T2 96-242 Sentence denotes Prostate cancer is the most common solid tumor in men, and it shares with all cancers the hallmark of elevated, nonhomeostatic cell proliferation.
TextSentencer_T3 243-363 Sentence denotes Here we have tested the hypothesis that the SONIC HEDGEHOG (SHH)-GLI signaling pathway is implicated in prostate cancer.
T3 243-363 Sentence denotes Here we have tested the hypothesis that the SONIC HEDGEHOG (SHH)-GLI signaling pathway is implicated in prostate cancer.
TextSentencer_T4 364-518 Sentence denotes We report expression of SHH-GLI pathway components in adult human prostate cancer, often with enhanced levels in tumors versus normal prostatic epithelia.
T4 364-518 Sentence denotes We report expression of SHH-GLI pathway components in adult human prostate cancer, often with enhanced levels in tumors versus normal prostatic epithelia.
TextSentencer_T5 519-653 Sentence denotes Blocking the pathway with cyclopamine or anti-SHH antibodies inhibits the proliferation of GLI1+/PSA+ primary prostate tumor cultures.
T5 519-653 Sentence denotes Blocking the pathway with cyclopamine or anti-SHH antibodies inhibits the proliferation of GLI1+/PSA+ primary prostate tumor cultures.
TextSentencer_T6 654-777 Sentence denotes Inversely, SHH can potentiate tumor cell proliferation, suggesting that autocrine signaling may often sustain tumor growth.
T6 654-777 Sentence denotes Inversely, SHH can potentiate tumor cell proliferation, suggesting that autocrine signaling may often sustain tumor growth.
TextSentencer_T7 778-1068 Sentence denotes In addition, pathway blockade in three metastatic prostate cancer cell lines with cyclopamine or through GLI1 RNA interference leads to inhibition of cell proliferation, suggesting cell-autonomous pathway activation at different levels and showing an essential role for GLI1 in human cells.
T7 778-1068 Sentence denotes In addition, pathway blockade in three metastatic prostate cancer cell lines with cyclopamine or through GLI1 RNA interference leads to inhibition of cell proliferation, suggesting cell-autonomous pathway activation at different levels and showing an essential role for GLI1 in human cells.
TextSentencer_T8 1069-1185 Sentence denotes Our data demonstrate the dependence of prostate cancer on SHH-GLI function and suggest a novel therapeutic approach.
T8 1069-1185 Sentence denotes Our data demonstrate the dependence of prostate cancer on SHH-GLI function and suggest a novel therapeutic approach.