| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-171 |
Sentence |
denotes |
Correlation of expression of multidrug resistance protein and messenger RNA with 99mTc-methoxyisobutyl isonitrile (MIBI) imaging in patients with hepatocellular carcinoma. |
| T1 |
0-171 |
Sentence |
denotes |
Correlation of expression of multidrug resistance protein and messenger RNA with 99mTc-methoxyisobutyl isonitrile (MIBI) imaging in patients with hepatocellular carcinoma. |
| TextSentencer_T2 |
172-176 |
Sentence |
denotes |
AIM: |
| T2 |
172-176 |
Sentence |
denotes |
AIM: |
| TextSentencer_T3 |
177-388 |
Sentence |
denotes |
To explore whether P-glycoprotein (Pgp) and other pumps, multidrug resistance-associated protein (MRP) and lung resistance protein (LRP), could affect tumor accumulation and efflux of 99mTc-MIBI in liver cancer. |
| T3 |
177-388 |
Sentence |
denotes |
To explore whether P-glycoprotein (Pgp) and other pumps, multidrug resistance-associated protein (MRP) and lung resistance protein (LRP), could affect tumor accumulation and efflux of 99mTc-MIBI in liver cancer. |
| TextSentencer_T4 |
389-397 |
Sentence |
denotes |
METHODS: |
| T4 |
389-397 |
Sentence |
denotes |
METHODS: |
| TextSentencer_T5 |
398-470 |
Sentence |
denotes |
Surgically treated 78 liver cancer patients were included in this study. |
| T5 |
398-470 |
Sentence |
denotes |
Surgically treated 78 liver cancer patients were included in this study. |
| TextSentencer_T6 |
471-588 |
Sentence |
denotes |
Before surgery, 99mTc-MIBI SPECT was performed 15 min and 120 min after injection of 20 mCi 99mTc-MIBI, respectively. |
| T6 |
471-588 |
Sentence |
denotes |
Before surgery, 99mTc-MIBI SPECT was performed 15 min and 120 min after injection of 20 mCi 99mTc-MIBI, respectively. |
| TextSentencer_T7 |
589-679 |
Sentence |
denotes |
Early uptake, delayed uptake (L/Nd), and washout rate (L/Nwr) of 99mTc-MIBI were obtained. |
| T7 |
589-679 |
Sentence |
denotes |
Early uptake, delayed uptake (L/Nd), and washout rate (L/Nwr) of 99mTc-MIBI were obtained. |
| TextSentencer_T8 |
680-777 |
Sentence |
denotes |
Expressions of Pgp, MRP and LRP were investigated with Western blotting and immunohistochemistry. |
| T8 |
680-777 |
Sentence |
denotes |
Expressions of Pgp, MRP and LRP were investigated with Western blotting and immunohistochemistry. |
| TextSentencer_T9 |
778-850 |
Sentence |
denotes |
Messenger RNA (mRNA) level of Pgp, MRP and LRP was determined by RT-PCR. |
| T9 |
778-850 |
Sentence |
denotes |
Messenger RNA (mRNA) level of Pgp, MRP and LRP was determined by RT-PCR. |
| TextSentencer_T10 |
851-859 |
Sentence |
denotes |
RESULTS: |
| T10 |
851-859 |
Sentence |
denotes |
RESULTS: |
| TextSentencer_T11 |
860-989 |
Sentence |
denotes |
No 99mTc-MIBI uptakes in tumor lesions of 68 of 78 (87.2%) patients with hepatocellular carcinoma were found on 99mTc-MIBI SPECT. |
| T11 |
860-989 |
Sentence |
denotes |
No 99mTc-MIBI uptakes in tumor lesions of 68 of 78 (87.2%) patients with hepatocellular carcinoma were found on 99mTc-MIBI SPECT. |
| TextSentencer_T12 |
990-1091 |
Sentence |
denotes |
P-gp expression was observed in tumor tissues of the patients with no uptake of 99mTc-MIBI (P<0.017). |
| T12 |
990-1091 |
Sentence |
denotes |
P-gp expression was observed in tumor tissues of the patients with no uptake of 99mTc-MIBI (P<0.017). |
| TextSentencer_T13 |
1092-1229 |
Sentence |
denotes |
No appreciable correlation was found between liver cancer 99mTc-MIBI images and expression of MRP or LRP on the level of protein or mRNA. |
| T13 |
1092-1229 |
Sentence |
denotes |
No appreciable correlation was found between liver cancer 99mTc-MIBI images and expression of MRP or LRP on the level of protein or mRNA. |
| TextSentencer_T14 |
1230-1241 |
Sentence |
denotes |
CONCLUSION: |
| T14 |
1230-1241 |
Sentence |
denotes |
CONCLUSION: |
| TextSentencer_T15 |
1242-1380 |
Sentence |
denotes |
99mTc-MIBI SPECT is noninvasive, and useful in predicting the presence of MDR1 gene-encoded Pgp in patients with hepatocellular carcinoma. |
| T15 |
1242-1380 |
Sentence |
denotes |
99mTc-MIBI SPECT is noninvasive, and useful in predicting the presence of MDR1 gene-encoded Pgp in patients with hepatocellular carcinoma. |