| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-96 |
Sentence |
denotes |
The heparan sulfate-specific epitope 10E4 is NO-sensitive and partly inaccessible in glypican-1. |
| T1 |
0-96 |
Sentence |
denotes |
The heparan sulfate-specific epitope 10E4 is NO-sensitive and partly inaccessible in glypican-1. |
| T1 |
0-96 |
Sentence |
denotes |
The heparan sulfate-specific epitope 10E4 is NO-sensitive and partly inaccessible in glypican-1. |
| TextSentencer_T2 |
97-260 |
Sentence |
denotes |
The monoclonal antibody 10E4, which recognizes an epitope supposed to contain N-unsubstituted glucosamine, is commonly used to trace heparan sulfate proteoglycans. |
| T2 |
97-260 |
Sentence |
denotes |
The monoclonal antibody 10E4, which recognizes an epitope supposed to contain N-unsubstituted glucosamine, is commonly used to trace heparan sulfate proteoglycans. |
| T2 |
97-260 |
Sentence |
denotes |
The monoclonal antibody 10E4, which recognizes an epitope supposed to contain N-unsubstituted glucosamine, is commonly used to trace heparan sulfate proteoglycans. |
| TextSentencer_T3 |
261-412 |
Sentence |
denotes |
It has not been fully clarified if the N-unsubstituted glucosamine is required for antibody recognition and if all heparan sulfates carry this epitope. |
| T3 |
261-412 |
Sentence |
denotes |
It has not been fully clarified if the N-unsubstituted glucosamine is required for antibody recognition and if all heparan sulfates carry this epitope. |
| T3 |
261-412 |
Sentence |
denotes |
It has not been fully clarified if the N-unsubstituted glucosamine is required for antibody recognition and if all heparan sulfates carry this epitope. |
| TextSentencer_T4 |
413-584 |
Sentence |
denotes |
Here we show that the epitope can contain N-unsubstituted glucosamine and that nitric oxide-generated deaminative cleavage at this residue in vivo can destroy the epitope. |
| T4 |
413-584 |
Sentence |
denotes |
Here we show that the epitope can contain N-unsubstituted glucosamine and that nitric oxide-generated deaminative cleavage at this residue in vivo can destroy the epitope. |
| T4 |
413-584 |
Sentence |
denotes |
Here we show that the epitope can contain N-unsubstituted glucosamine and that nitric oxide-generated deaminative cleavage at this residue in vivo can destroy the epitope. |
| TextSentencer_T5 |
585-806 |
Sentence |
denotes |
Studies using flow cytometry and confocal immunofluorescence microscopy of both normal and transformed cells indicated that the 10E4 epitope was partially inaccessible in the heparan sulfate chains attached to glypican-1. |
| T5 |
585-806 |
Sentence |
denotes |
Studies using flow cytometry and confocal immunofluorescence microscopy of both normal and transformed cells indicated that the 10E4 epitope was partially inaccessible in the heparan sulfate chains attached to glypican-1. |
| T5 |
585-806 |
Sentence |
denotes |
Studies using flow cytometry and confocal immunofluorescence microscopy of both normal and transformed cells indicated that the 10E4 epitope was partially inaccessible in the heparan sulfate chains attached to glypican-1. |
| TextSentencer_T6 |
807-919 |
Sentence |
denotes |
The 10E4 antibody recognized mainly heparan sulfate degradation products that colocalized with acidic endosomes. |
| T6 |
807-919 |
Sentence |
denotes |
The 10E4 antibody recognized mainly heparan sulfate degradation products that colocalized with acidic endosomes. |
| T6 |
807-919 |
Sentence |
denotes |
The 10E4 antibody recognized mainly heparan sulfate degradation products that colocalized with acidic endosomes. |
| TextSentencer_T7 |
920-1023 |
Sentence |
denotes |
These sites were greatly depleted of 10E4-positive heparan sulfate on suramin inhibition of heparanase. |
| T7 |
920-1023 |
Sentence |
denotes |
These sites were greatly depleted of 10E4-positive heparan sulfate on suramin inhibition of heparanase. |
| T7 |
920-1023 |
Sentence |
denotes |
These sites were greatly depleted of 10E4-positive heparan sulfate on suramin inhibition of heparanase. |
| TextSentencer_T8 |
1024-1121 |
Sentence |
denotes |
Instead, there was increased colocalization between 10E4-positive heparan sulfate and glypican-1. |
| T8 |
1024-1121 |
Sentence |
denotes |
Instead, there was increased colocalization between 10E4-positive heparan sulfate and glypican-1. |
| T8 |
1024-1121 |
Sentence |
denotes |
Instead, there was increased colocalization between 10E4-positive heparan sulfate and glypican-1. |
| TextSentencer_T9 |
1122-1249 |
Sentence |
denotes |
When both S-nitrosylation of Gpc-1 and heparanase were inhibited, detectable 10E4 epitope colocalized entirely with glypican-1. |
| T9 |
1122-1249 |
Sentence |
denotes |
When both S-nitrosylation of Gpc-1 and heparanase were inhibited, detectable 10E4 epitope colocalized entirely with glypican-1. |
| T9 |
1122-1249 |
Sentence |
denotes |
When both S-nitrosylation of Gpc-1 and heparanase were inhibited, detectable 10E4 epitope colocalized entirely with glypican-1. |
| TextSentencer_T10 |
1250-1372 |
Sentence |
denotes |
In nitric oxide-depleted cells, there was both an increased signal from 10E4 and increased colocalization with glypican-1. |
| T10 |
1250-1372 |
Sentence |
denotes |
In nitric oxide-depleted cells, there was both an increased signal from 10E4 and increased colocalization with glypican-1. |
| T10 |
1250-1372 |
Sentence |
denotes |
In nitric oxide-depleted cells, there was both an increased signal from 10E4 and increased colocalization with glypican-1. |
| TextSentencer_T11 |
1373-1554 |
Sentence |
denotes |
In suramin-treated cells, the 10E4 epitope was destroyed by ascorbate-released nitric oxide with concomitant formation of anhydromannose-containing heparan sulfate oligosaccharides. |
| T11 |
1373-1554 |
Sentence |
denotes |
In suramin-treated cells, the 10E4 epitope was destroyed by ascorbate-released nitric oxide with concomitant formation of anhydromannose-containing heparan sulfate oligosaccharides. |
| T11 |
1373-1554 |
Sentence |
denotes |
In suramin-treated cells, the 10E4 epitope was destroyed by ascorbate-released nitric oxide with concomitant formation of anhydromannose-containing heparan sulfate oligosaccharides. |
| TextSentencer_T12 |
1555-1770 |
Sentence |
denotes |
Immunoisolation of radiolabeled 10E4-positive material from unperturbed cells yielded very little glypican-1 when compared with specifically immunoisolated glypican-1 and total proteoglycan and degradation products. |
| T12 |
1555-1770 |
Sentence |
denotes |
Immunoisolation of radiolabeled 10E4-positive material from unperturbed cells yielded very little glypican-1 when compared with specifically immunoisolated glypican-1 and total proteoglycan and degradation products. |
| T12 |
1555-1770 |
Sentence |
denotes |
Immunoisolation of radiolabeled 10E4-positive material from unperturbed cells yielded very little glypican-1 when compared with specifically immunoisolated glypican-1 and total proteoglycan and degradation products. |
| TextSentencer_T13 |
1771-1883 |
Sentence |
denotes |
The 10E4 immunoisolates were either other heparan sulfate proteoglycans or heparan sulfate degradation products. |
| T13 |
1771-1883 |
Sentence |
denotes |
The 10E4 immunoisolates were either other heparan sulfate proteoglycans or heparan sulfate degradation products. |
| T13 |
1771-1883 |
Sentence |
denotes |
The 10E4 immunoisolates were either other heparan sulfate proteoglycans or heparan sulfate degradation products. |