> top > projects > sentences > docs > PubMed:15041272 > annotations
sentences Home  

PubMed:15041272 JSONTXT 19 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-88 Sentence denotes A first Taiwanese Chinese family of type 2B von Willebrand disease with R1306W mutation.
T1 0-88 Sentence denotes A first Taiwanese Chinese family of type 2B von Willebrand disease with R1306W mutation.
TextSentencer_T2 89-206 Sentence denotes Clinical, laboratory and genetic defect of a Taiwanese family with type 2B von Willebrand disease (VWD) were studied.
T2 89-206 Sentence denotes Clinical, laboratory and genetic defect of a Taiwanese family with type 2B von Willebrand disease (VWD) were studied.
TextSentencer_T3 207-320 Sentence denotes The proband was a 55-year-old woman who gave birth to two daughters and one son aged 30, 29 and 27, respectively.
T3 207-320 Sentence denotes The proband was a 55-year-old woman who gave birth to two daughters and one son aged 30, 29 and 27, respectively.
TextSentencer_T4 321-384 Sentence denotes All had abnormal mucocutaneous bleedings since their childhood.
T4 321-384 Sentence denotes All had abnormal mucocutaneous bleedings since their childhood.
TextSentencer_T5 385-705 Sentence denotes In proband, PT, PTT and platelet count were normal; template bleeding time was 14 min; VIII:C was 51%, von Willebrand factor antigen (VWF:Ag), 42% and von Willerand factor ristocetin-cofactor (VWF:RCo, 15%); ristocetin-induced platelet aggregation (RIPA) at 0.3 and 0.6 mg/ml of ristocetin was 16% and 68%, respectively.
T5 385-705 Sentence denotes In proband, PT, PTT and platelet count were normal; template bleeding time was 14 min; VIII:C was 51%, von Willebrand factor antigen (VWF:Ag), 42% and von Willerand factor ristocetin-cofactor (VWF:RCo, 15%); ristocetin-induced platelet aggregation (RIPA) at 0.3 and 0.6 mg/ml of ristocetin was 16% and 68%, respectively.
TextSentencer_T6 706-816 Sentence denotes The enhanced response to ristocetin was identified to be in plasma, not in platelet itself, by mixing studies.
T6 706-816 Sentence denotes The enhanced response to ristocetin was identified to be in plasma, not in platelet itself, by mixing studies.
TextSentencer_T7 817-952 Sentence denotes Analysis of von Willebrand factor (VWF) multimer of plasma but not of platelets showed absence of high-molecular weight (HMW) multimer.
T7 817-952 Sentence denotes Analysis of von Willebrand factor (VWF) multimer of plasma but not of platelets showed absence of high-molecular weight (HMW) multimer.
TextSentencer_T8 953-1004 Sentence denotes All three children had similar laboratory findings.
T8 953-1004 Sentence denotes All three children had similar laboratory findings.
TextSentencer_T9 1005-1091 Sentence denotes Exon 28 of VWF gene was amplified using polymerase chain reaction (PCR) and sequenced.
T9 1005-1091 Sentence denotes Exon 28 of VWF gene was amplified using polymerase chain reaction (PCR) and sequenced.
TextSentencer_T10 1092-1246 Sentence denotes The proband and three children were all found to be heterozygous for C to T transition at nucleotide 3916 resulting in Arg 1306 Trp (R1306W) substitution.
T10 1092-1246 Sentence denotes The proband and three children were all found to be heterozygous for C to T transition at nucleotide 3916 resulting in Arg 1306 Trp (R1306W) substitution.
TextSentencer_T11 1247-1437 Sentence denotes This mutation in the glycoprotein Ib (GPIb)-binding site has been found to increase the affinity of plasma VWF for platelets, and thus cause loss of HMW multimers and often thrombocytopenia.
T11 1247-1437 Sentence denotes This mutation in the glycoprotein Ib (GPIb)-binding site has been found to increase the affinity of plasma VWF for platelets, and thus cause loss of HMW multimers and often thrombocytopenia.
TextSentencer_T12 1438-1564 Sentence denotes In conclusion, a first report of type 2B VWD in a Taiwanese Chinese family who show R1306W mutation in VWF gene was described.
T12 1438-1564 Sentence denotes In conclusion, a first report of type 2B VWD in a Taiwanese Chinese family who show R1306W mutation in VWF gene was described.