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PubMed:14758071 JSONTXT 25 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-68 Sentence denotes Galectin-1 plays essential roles in adult mammalian nervous tissues.
T1 0-68 Sentence denotes Galectin-1 plays essential roles in adult mammalian nervous tissues.
TextSentencer_T2 69-98 Sentence denotes Roles of oxidized galectin-1.
T2 69-98 Sentence denotes Roles of oxidized galectin-1.
TextSentencer_T3 99-279 Sentence denotes Previous data have suggested that galectin-1 is expressed widely in nervous tissues at embryonic stages but becomes restricted mainly to peripheral nervous tissues with maturation.
T3 99-279 Sentence denotes Previous data have suggested that galectin-1 is expressed widely in nervous tissues at embryonic stages but becomes restricted mainly to peripheral nervous tissues with maturation.
TextSentencer_T4 280-413 Sentence denotes Though the expression is intense in adult mammalian peripheral neurons, there had been no report about functions of galectin-1 there.
T4 280-413 Sentence denotes Though the expression is intense in adult mammalian peripheral neurons, there had been no report about functions of galectin-1 there.
TextSentencer_T5 414-491 Sentence denotes Recently we discovered a factor that enhanced peripheral axonal regeneration.
T5 414-491 Sentence denotes Recently we discovered a factor that enhanced peripheral axonal regeneration.
TextSentencer_T6 492-613 Sentence denotes The factor was identified as oxidized galectin-1 with three intramolecular disulfide bonds and showed no lectin activity.
T6 492-613 Sentence denotes The factor was identified as oxidized galectin-1 with three intramolecular disulfide bonds and showed no lectin activity.
TextSentencer_T7 614-856 Sentence denotes Oxidized recombinant human galectin-1 (rhGAL-1/Ox) showed the same nerve growth promoting activity at very low concentrations (pg/ml). rhGAL-1/Ox at similarly low concentration was also effective in in vivo experiments of axonal regeneration.
T7 614-856 Sentence denotes Oxidized recombinant human galectin-1 (rhGAL-1/Ox) showed the same nerve growth promoting activity at very low concentrations (pg/ml). rhGAL-1/Ox at similarly low concentration was also effective in in vivo experiments of axonal regeneration.
TextSentencer_T8 857-990 Sentence denotes Moreover, the application of functional anti-rhGAL-1 antibody strongly inhibited the axonal regeneration in vivo as well as in vitro.
T8 857-990 Sentence denotes Moreover, the application of functional anti-rhGAL-1 antibody strongly inhibited the axonal regeneration in vivo as well as in vitro.
TextSentencer_T9 991-1278 Sentence denotes Since galectin-1 is expressed in the regenerating sciatic nerves as well as in both sensory neurons and motor neurons, these results suggest that galectin-1 is secreted into the extracellular space to be oxidized, and then, in its oxidized form, to regulate initial repair after axotomy.
T9 991-1278 Sentence denotes Since galectin-1 is expressed in the regenerating sciatic nerves as well as in both sensory neurons and motor neurons, these results suggest that galectin-1 is secreted into the extracellular space to be oxidized, and then, in its oxidized form, to regulate initial repair after axotomy.
TextSentencer_T10 1279-1397 Sentence denotes The administration of oxidized galectin-1 effectively promoted functional recovery after sciatic nerve injury in vivo.
T10 1279-1397 Sentence denotes The administration of oxidized galectin-1 effectively promoted functional recovery after sciatic nerve injury in vivo.
TextSentencer_T11 1398-1541 Sentence denotes Oxidized galectin-1, hence, appears to play an important role in promoting axonal regeneration, working as a kind of cytokine, not as a lectin.
T11 1398-1541 Sentence denotes Oxidized galectin-1, hence, appears to play an important role in promoting axonal regeneration, working as a kind of cytokine, not as a lectin.
TextSentencer_T12 1542-1640 Sentence denotes Recent reports indicated additional roles of cytosolic galectin-1 in neural diseases, such as ALS.
T12 1542-1640 Sentence denotes Recent reports indicated additional roles of cytosolic galectin-1 in neural diseases, such as ALS.
TextSentencer_T13 1641-1719 Sentence denotes Furthermore galectin-1 has been proved to be a downstream target of DeltaFosB.
T13 1641-1719 Sentence denotes Furthermore galectin-1 has been proved to be a downstream target of DeltaFosB.
TextSentencer_T14 1720-1920 Sentence denotes In hippocampus of rat brain, expression of DeltaFosB is induced immediately after ischemia-reperfusion, suggesting that galectin-1 may also play important roles in central nervous system after injury.
T14 1720-1920 Sentence denotes In hippocampus of rat brain, expression of DeltaFosB is induced immediately after ischemia-reperfusion, suggesting that galectin-1 may also play important roles in central nervous system after injury.