> top > projects > sentences > docs > PubMed:14743461 > annotations
sentences Home  

PubMed:14743461 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-63 Sentence denotes Characteristics of prostate cancers detected at low PSA levels.
T1 0-63 Sentence denotes Characteristics of prostate cancers detected at low PSA levels.
TextSentencer_T2 64-75 Sentence denotes BACKGROUND:
T2 64-75 Sentence denotes BACKGROUND:
TextSentencer_T3 76-274 Sentence denotes When age-referenced PSA levels as recommended by Oesterling et al.1 were used as a biopsy criterion, only 25% of the cancers detected in a population based PSA Screening Project were organ-confined.
T3 76-274 Sentence denotes When age-referenced PSA levels as recommended by Oesterling et al.1 were used as a biopsy criterion, only 25% of the cancers detected in a population based PSA Screening Project were organ-confined.
TextSentencer_T4 275-368 Sentence denotes This observation led to the decision to use low PSA levels as the sole indication for biopsy.
T4 275-368 Sentence denotes This observation led to the decision to use low PSA levels as the sole indication for biopsy.
TextSentencer_T5 369-496 Sentence denotes Since 1995 age-referenced PSA levels of 1.25-3.25 ng/ml have been used in combination with a percentage free PSA cutoff of 18%.
T5 369-496 Sentence denotes Since 1995 age-referenced PSA levels of 1.25-3.25 ng/ml have been used in combination with a percentage free PSA cutoff of 18%.
TextSentencer_T6 497-663 Sentence denotes This PSA cutoff reduction led to a statistically significant migration to lower pathological stages with a decreased prostate cancer mortality in the years 1996-2001.
T6 497-663 Sentence denotes This PSA cutoff reduction led to a statistically significant migration to lower pathological stages with a decreased prostate cancer mortality in the years 1996-2001.
TextSentencer_T7 664-778 Sentence denotes However, concerns have been raised that screening with low PSA levels may detect clinically insignificant cancers.
T7 664-778 Sentence denotes However, concerns have been raised that screening with low PSA levels may detect clinically insignificant cancers.
TextSentencer_T8 779-801 Sentence denotes MATERIALS AND METHODS:
T8 779-801 Sentence denotes MATERIALS AND METHODS:
TextSentencer_T9 802-984 Sentence denotes We evaluated prostate cancer patients with low PSA levels in terms of heterogeneity, clinical significance, multifocality, and tumor biology including ploidy and proliferation index.
T9 802-984 Sentence denotes We evaluated prostate cancer patients with low PSA levels in terms of heterogeneity, clinical significance, multifocality, and tumor biology including ploidy and proliferation index.
TextSentencer_T10 985-993 Sentence denotes RESULTS:
T10 985-993 Sentence denotes RESULTS:
TextSentencer_T11 994-1408 Sentence denotes Concerning heterogeneity the Gleason score of the needle biopsy failed to predict the Gleason score of the radical prostatectomy specimen in nearly 40% of prostate cancer patients; regarding multifocality 65% of patients with low PSA levels showed multifocal lesions and 36% exhibited tetraploid DNA distribution; more than 50% of tetraploid tumors were found in patients with tumor volumes of less than 0.5 cm(3).
T11 994-1408 Sentence denotes Concerning heterogeneity the Gleason score of the needle biopsy failed to predict the Gleason score of the radical prostatectomy specimen in nearly 40% of prostate cancer patients; regarding multifocality 65% of patients with low PSA levels showed multifocal lesions and 36% exhibited tetraploid DNA distribution; more than 50% of tetraploid tumors were found in patients with tumor volumes of less than 0.5 cm(3).
TextSentencer_T12 1409-1489 Sentence denotes Ploidy correlated with the Ki-67 proliferation index, but not with tumor volume.
T12 1409-1489 Sentence denotes Ploidy correlated with the Ki-67 proliferation index, but not with tumor volume.
TextSentencer_T13 1490-1502 Sentence denotes CONCLUSIONS:
T13 1490-1502 Sentence denotes CONCLUSIONS:
TextSentencer_T14 1503-1783 Sentence denotes These results demonstrate that small prostate cancers with low PSA levels and low tumor volumes exhibit all features of prostate cancers with higher tumor volumes and show the characteristics of malignant cancers, i.e., multifocality, tetraploidy, and high proliferative activity.
T14 1503-1783 Sentence denotes These results demonstrate that small prostate cancers with low PSA levels and low tumor volumes exhibit all features of prostate cancers with higher tumor volumes and show the characteristics of malignant cancers, i.e., multifocality, tetraploidy, and high proliferative activity.