| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-90 |
Sentence |
denotes |
Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. |
| T1 |
0-90 |
Sentence |
denotes |
Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. |
| T2 |
91-217 |
Sentence |
denotes |
Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. |
| T2 |
91-217 |
Sentence |
denotes |
Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. |
| T3 |
218-389 |
Sentence |
denotes |
We and others have previously described the isolation of three human alpha (1,3)fucosyltransferase genes which form the basis of a nascent glycosyltransferase gene family. |
| T3 |
218-389 |
Sentence |
denotes |
We and others have previously described the isolation of three human alpha (1,3)fucosyltransferase genes which form the basis of a nascent glycosyltransferase gene family. |
| T4 |
390-505 |
Sentence |
denotes |
We now report the molecular cloning and expression of a fourth homologous human alpha (1,3)fucosyltransferase gene. |
| T4 |
390-505 |
Sentence |
denotes |
We now report the molecular cloning and expression of a fourth homologous human alpha (1,3)fucosyltransferase gene. |
| T5 |
506-885 |
Sentence |
denotes |
When transfected into mammalian cells, this fucosyltransferase gene is capable of directing expression of the Lewis x (Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc), sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4 [Fuc alpha 1-->3]GlcNAc), and difucosyl sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc beta 1-->3 Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc) epitopes. |
| T5 |
506-885 |
Sentence |
denotes |
When transfected into mammalian cells, this fucosyltransferase gene is capable of directing expression of the Lewis x (Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc), sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4 [Fuc alpha 1-->3]GlcNAc), and difucosyl sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc beta 1-->3 Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc) epitopes. |
| T6 |
886-1045 |
Sentence |
denotes |
The enzyme shares 85% amino acid sequence identity with Fuc-TIII and 89% identity with Fuc-TV but differs substantially in its acceptor substrate requirements. |
| T6 |
886-1045 |
Sentence |
denotes |
The enzyme shares 85% amino acid sequence identity with Fuc-TIII and 89% identity with Fuc-TV but differs substantially in its acceptor substrate requirements. |
| T7 |
1046-1159 |
Sentence |
denotes |
Polymerase chain reaction analyses demonstrate that the gene is syntenic to Fuc-TIII and Fuc-TV on chromosome 19. |
| T7 |
1046-1159 |
Sentence |
denotes |
Polymerase chain reaction analyses demonstrate that the gene is syntenic to Fuc-TIII and Fuc-TV on chromosome 19. |
| T8 |
1160-1372 |
Sentence |
denotes |
Southern blot analyses of human genomic DNA demonstrate that these four alpha (1,3)fucosyltransferase genes account for all DNA sequences that cross-hybridize at low stringency with the Fuc-TIII catalytic domain. |
| T8 |
1160-1372 |
Sentence |
denotes |
Southern blot analyses of human genomic DNA demonstrate that these four alpha (1,3)fucosyltransferase genes account for all DNA sequences that cross-hybridize at low stringency with the Fuc-TIII catalytic domain. |
| T9 |
1373-1552 |
Sentence |
denotes |
Using similar methods, a catalytic domain probe from Fuc-TIV identifies a new class of DNA fragments which do not cross-hybridize with the chromosome 19 fucosyltransferase probes. |
| T9 |
1373-1552 |
Sentence |
denotes |
Using similar methods, a catalytic domain probe from Fuc-TIV identifies a new class of DNA fragments which do not cross-hybridize with the chromosome 19 fucosyltransferase probes. |
| T10 |
1553-1723 |
Sentence |
denotes |
These results extend the molecular definition of a family of human alpha (1,3)fucosyltransferase genes and provide tools for examining fucosyltransferase gene expression. |
| T10 |
1553-1723 |
Sentence |
denotes |
These results extend the molecular definition of a family of human alpha (1,3)fucosyltransferase genes and provide tools for examining fucosyltransferase gene expression. |