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PubMed:12826670 JSONTXT 41 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-42 Sentence denotes Transport kinetics of uncoupling proteins.
T1 0-42 Sentence denotes Transport kinetics of uncoupling proteins.
TextSentencer_T2 43-99 Sentence denotes Analysis of UCP1 reconstituted in planar lipid bilayers.
T2 43-99 Sentence denotes Analysis of UCP1 reconstituted in planar lipid bilayers.
TextSentencer_T3 100-279 Sentence denotes According to alternative hypotheses, mitochondrial uncoupling protein 1 (UCP1) is either a proton channel ("buffering model") or a fatty acid anion carrier ("fatty acid cycling").
T3 100-279 Sentence denotes According to alternative hypotheses, mitochondrial uncoupling protein 1 (UCP1) is either a proton channel ("buffering model") or a fatty acid anion carrier ("fatty acid cycling").
TextSentencer_T4 280-447 Sentence denotes Transport across the proton channel along a chain of hydrogen bonds (Grotthus mechanism) may include fatty acid carboxyl groups or occur in the absence of fatty acids.
T4 280-447 Sentence denotes Transport across the proton channel along a chain of hydrogen bonds (Grotthus mechanism) may include fatty acid carboxyl groups or occur in the absence of fatty acids.
TextSentencer_T5 448-610 Sentence denotes In this work, we demonstrate that planar bilayers reconstituted with UCP1 exhibit an increase in membrane conductivity exclusively in the presence of fatty acids.
T5 448-610 Sentence denotes In this work, we demonstrate that planar bilayers reconstituted with UCP1 exhibit an increase in membrane conductivity exclusively in the presence of fatty acids.
TextSentencer_T6 611-741 Sentence denotes Hence, we can exclude the hypothesis considering a preexisting H+ channel in UCP1, which does not require fatty acid for function.
T6 611-741 Sentence denotes Hence, we can exclude the hypothesis considering a preexisting H+ channel in UCP1, which does not require fatty acid for function.
TextSentencer_T7 742-805 Sentence denotes The augmented conductivity is nearly completely blocked by ATP.
T7 742-805 Sentence denotes The augmented conductivity is nearly completely blocked by ATP.
TextSentencer_T8 806-1036 Sentence denotes Direct application of transmembrane voltage and precise current measurements allowed determination of ATP-sensitive conductances at 0 and 150 mV as 11.5 and 54.3 pS, respectively, by reconstituting nearly 3 x 10(5) copies of UCP1.
T8 806-1036 Sentence denotes Direct application of transmembrane voltage and precise current measurements allowed determination of ATP-sensitive conductances at 0 and 150 mV as 11.5 and 54.3 pS, respectively, by reconstituting nearly 3 x 10(5) copies of UCP1.
TextSentencer_T9 1037-1191 Sentence denotes The proton conductivity measurements carried out in presence of a pH gradient (0.4 units) allowed estimation of proton turnover numbers per UCP1 molecule.
T9 1037-1191 Sentence denotes The proton conductivity measurements carried out in presence of a pH gradient (0.4 units) allowed estimation of proton turnover numbers per UCP1 molecule.
TextSentencer_T10 1192-1289 Sentence denotes The observed transport rate of 14 s-1 is compatible both with carrier and channel nature of UCP1.
T10 1192-1289 Sentence denotes The observed transport rate of 14 s-1 is compatible both with carrier and channel nature of UCP1.