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PubMed:12773477 JSONTXT 55 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-65 Sentence denotes Modulation of prion protein structural integrity by geldanamycin.
T1 0-65 Sentence denotes Modulation of prion protein structural integrity by geldanamycin.
T1 0-65 Sentence denotes Modulation of prion protein structural integrity by geldanamycin.
TextSentencer_T2 66-222 Sentence denotes The cellular prion protein PrPc is of crucial importance for the development of neurodegenerative diseases called transmissible spongiform encephalopathies.
T2 66-222 Sentence denotes The cellular prion protein PrPc is of crucial importance for the development of neurodegenerative diseases called transmissible spongiform encephalopathies.
T2 66-222 Sentence denotes The cellular prion protein PrPc is of crucial importance for the development of neurodegenerative diseases called transmissible spongiform encephalopathies.
TextSentencer_T3 223-371 Sentence denotes We investigated if the function of members of the HSP90 family is required for the integrity of the normal, nonpathogenic prion protein called PrPc.
T3 223-371 Sentence denotes We investigated if the function of members of the HSP90 family is required for the integrity of the normal, nonpathogenic prion protein called PrPc.
T3 223-371 Sentence denotes We investigated if the function of members of the HSP90 family is required for the integrity of the normal, nonpathogenic prion protein called PrPc.
TextSentencer_T4 372-487 Sentence denotes Eukaryotic cells were treated with the structurally unrelated HSP90-inhibitors geldanamycin (GA) or radicicol (RC).
T4 372-487 Sentence denotes Eukaryotic cells were treated with the structurally unrelated HSP90-inhibitors geldanamycin (GA) or radicicol (RC).
T4 372-487 Sentence denotes Eukaryotic cells were treated with the structurally unrelated HSP90-inhibitors geldanamycin (GA) or radicicol (RC).
TextSentencer_T5 488-689 Sentence denotes In either case the cellular prion protein was induced and exhibited faster migrating bands on western blot analysis, whereas geldampicin (GE), an analog of GA known not to bind to HSP90, had no effect.
T5 488-689 Sentence denotes In either case the cellular prion protein was induced and exhibited faster migrating bands on western blot analysis, whereas geldampicin (GE), an analog of GA known not to bind to HSP90, had no effect.
T5 488-689 Sentence denotes In either case the cellular prion protein was induced and exhibited faster migrating bands on western blot analysis, whereas geldampicin (GE), an analog of GA known not to bind to HSP90, had no effect.
TextSentencer_T6 690-812 Sentence denotes Ongoing protein and messenger RNA synthesis during treatment were found to be necessary for the appearance of these bands.
T6 690-812 Sentence denotes Ongoing protein and messenger RNA synthesis during treatment were found to be necessary for the appearance of these bands.
T6 690-812 Sentence denotes Ongoing protein and messenger RNA synthesis during treatment were found to be necessary for the appearance of these bands.
TextSentencer_T7 813-913 Sentence denotes Cotreatment with tunicamycin abrogated any effect of HSP90 inhibitors on the cellular prion protein.
T7 813-913 Sentence denotes Cotreatment with tunicamycin abrogated any effect of HSP90 inhibitors on the cellular prion protein.
T7 813-913 Sentence denotes Cotreatment with tunicamycin abrogated any effect of HSP90 inhibitors on the cellular prion protein.
TextSentencer_T8 914-1103 Sentence denotes Finally, enzymatic deglycosylation with peptide:N-glycosidase F of the normal prion protein as well as the variant induced by benzoquinone ansamycins resulted in very similar band patterns.
T8 914-1103 Sentence denotes Finally, enzymatic deglycosylation with peptide:N-glycosidase F of the normal prion protein as well as the variant induced by benzoquinone ansamycins resulted in very similar band patterns.
T8 914-1103 Sentence denotes Finally, enzymatic deglycosylation with peptide:N-glycosidase F of the normal prion protein as well as the variant induced by benzoquinone ansamycins resulted in very similar band patterns.
TextSentencer_T9 1104-1279 Sentence denotes These experiments indicate that either altered glycosylation, or a change in conformation, or both are involved in the induction of faster migrating bands by HSP90 inhibitors.
T9 1104-1279 Sentence denotes These experiments indicate that either altered glycosylation, or a change in conformation, or both are involved in the induction of faster migrating bands by HSP90 inhibitors.
T9 1104-1279 Sentence denotes These experiments indicate that either altered glycosylation, or a change in conformation, or both are involved in the induction of faster migrating bands by HSP90 inhibitors.
TextSentencer_T10 1280-1441 Sentence denotes Thus the inhibition of the function of members of the HSP90 family of molecular chaperones results in profound changes in the physicochemical properties of PrPc.
T10 1280-1441 Sentence denotes Thus the inhibition of the function of members of the HSP90 family of molecular chaperones results in profound changes in the physicochemical properties of PrPc.
T10 1280-1441 Sentence denotes Thus the inhibition of the function of members of the HSP90 family of molecular chaperones results in profound changes in the physicochemical properties of PrPc.