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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-94 Sentence denotes Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells.
T1 0-94 Sentence denotes Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells.
TextSentencer_T2 95-179 Sentence denotes Langerin is a type II transmembrane cell surface receptor found on Langerhans cells.
T2 95-179 Sentence denotes Langerin is a type II transmembrane cell surface receptor found on Langerhans cells.
TextSentencer_T3 180-343 Sentence denotes The extracellular domain of langerin consists of a neck region containing a series of heptad repeats and a C-terminal C-type carbohydrate-recognition domain (CRD).
T3 180-343 Sentence denotes The extracellular domain of langerin consists of a neck region containing a series of heptad repeats and a C-terminal C-type carbohydrate-recognition domain (CRD).
TextSentencer_T4 344-488 Sentence denotes A role for langerin in processing of glycoprotein antigens has been proposed, but until now there has been little study of the langerin protein.
T4 344-488 Sentence denotes A role for langerin in processing of glycoprotein antigens has been proposed, but until now there has been little study of the langerin protein.
TextSentencer_T5 489-792 Sentence denotes In this study, analytical ultracentrifugation and circular dichroism spectroscopy of recombinant soluble fragments of human langerin have been used to show that the extracellular region of this receptor exists as a stable trimer held together by a coiled coil of alpha-helices formed by the neck region.
T5 489-792 Sentence denotes In this study, analytical ultracentrifugation and circular dichroism spectroscopy of recombinant soluble fragments of human langerin have been used to show that the extracellular region of this receptor exists as a stable trimer held together by a coiled coil of alpha-helices formed by the neck region.
TextSentencer_T6 793-943 Sentence denotes The langerin CRD shows specificity for mannose, GlcNAc, and fucose, but only the trimeric extracellular domain fragment binds to glycoprotein ligands.
T6 793-943 Sentence denotes The langerin CRD shows specificity for mannose, GlcNAc, and fucose, but only the trimeric extracellular domain fragment binds to glycoprotein ligands.
TextSentencer_T7 944-1122 Sentence denotes Langerin extracellular domain binds mammalian high mannose oligosaccharides, as well mannose-containing structures on yeast invertase but does not bind complex glycan structures.
T7 944-1122 Sentence denotes Langerin extracellular domain binds mammalian high mannose oligosaccharides, as well mannose-containing structures on yeast invertase but does not bind complex glycan structures.
TextSentencer_T8 1123-1408 Sentence denotes Full-length langerin stably expressed in rat fibroblast transfectants mediates efficient uptake and degradation of a mannosylated neoglycoprotein ligand. pH-dependent ligand release appears to involve interactions between the CRDs or between the CRDs and the neck region in the trimer.
T8 1123-1408 Sentence denotes Full-length langerin stably expressed in rat fibroblast transfectants mediates efficient uptake and degradation of a mannosylated neoglycoprotein ligand. pH-dependent ligand release appears to involve interactions between the CRDs or between the CRDs and the neck region in the trimer.
TextSentencer_T9 1409-1527 Sentence denotes The results are consistent with a role for langerin in internalization of both self and nonself glycoprotein antigens.
T9 1409-1527 Sentence denotes The results are consistent with a role for langerin in internalization of both self and nonself glycoprotein antigens.