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PubMed:12549952 JSONTXT 26 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-70 Sentence denotes Acute liver failure with concurrent bupropion and carbimazole therapy.
T1 0-70 Sentence denotes Acute liver failure with concurrent bupropion and carbimazole therapy.
TextSentencer_T2 71-81 Sentence denotes OBJECTIVE:
T2 71-81 Sentence denotes OBJECTIVE:
TextSentencer_T3 82-191 Sentence denotes To report a case of fatal liver failure possibly associated with concurrent use of bupropion and carbimazole.
T3 82-191 Sentence denotes To report a case of fatal liver failure possibly associated with concurrent use of bupropion and carbimazole.
TextSentencer_T4 192-205 Sentence denotes CASE SUMMARY:
T4 192-205 Sentence denotes CASE SUMMARY:
TextSentencer_T5 206-337 Sentence denotes A 41-year-old Chinese man with a history of hyperthyroidism had been treated with carbimazole and propranolol for the past 5 years.
T5 206-337 Sentence denotes A 41-year-old Chinese man with a history of hyperthyroidism had been treated with carbimazole and propranolol for the past 5 years.
TextSentencer_T6 338-442 Sentence denotes He received a 10-day course of bupropion as an aid for smoking cessation 10 weeks prior to presentation.
T6 338-442 Sentence denotes He received a 10-day course of bupropion as an aid for smoking cessation 10 weeks prior to presentation.
TextSentencer_T7 443-519 Sentence denotes He developed acute liver failure with rapid deterioration of renal function.
T7 443-519 Sentence denotes He developed acute liver failure with rapid deterioration of renal function.
TextSentencer_T8 520-596 Sentence denotes Liver biopsy showed evidence of nonspecific drug-induced acute liver injury.
T8 520-596 Sentence denotes Liver biopsy showed evidence of nonspecific drug-induced acute liver injury.
TextSentencer_T9 597-662 Sentence denotes His condition was further complicated by sepsis and coagulopathy.
T9 597-662 Sentence denotes His condition was further complicated by sepsis and coagulopathy.
TextSentencer_T10 663-714 Sentence denotes Death resulted 19 days after the onset of symptoms.
T10 663-714 Sentence denotes Death resulted 19 days after the onset of symptoms.
TextSentencer_T11 715-836 Sentence denotes The likelihood that bupropion induced hepatotoxicity in our patient was possible, based on the Naranjo probability scale.
T11 715-836 Sentence denotes The likelihood that bupropion induced hepatotoxicity in our patient was possible, based on the Naranjo probability scale.
TextSentencer_T12 837-848 Sentence denotes DISCUSSION:
T12 837-848 Sentence denotes DISCUSSION:
TextSentencer_T13 849-1093 Sentence denotes Although there is increasing evidence of hepatotoxicity induced by bupropion, this is the first case of fatality that could have resulted from acute liver failure in a patient receiving bupropion while on concomitant treatment with carbimazole.
T13 849-1093 Sentence denotes Although there is increasing evidence of hepatotoxicity induced by bupropion, this is the first case of fatality that could have resulted from acute liver failure in a patient receiving bupropion while on concomitant treatment with carbimazole.
TextSentencer_T14 1094-1106 Sentence denotes CONCLUSIONS:
T14 1094-1106 Sentence denotes CONCLUSIONS:
TextSentencer_T15 1107-1244 Sentence denotes Clinicians should be aware of the possibility of acute liver insult induced by bupropion given concurrently with other hepatotoxic drugs.
T15 1107-1244 Sentence denotes Clinicians should be aware of the possibility of acute liver insult induced by bupropion given concurrently with other hepatotoxic drugs.