| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-125 |
Sentence |
denotes |
TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans. |
| T1 |
0-125 |
Sentence |
denotes |
TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans. |
| T1 |
0-125 |
Sentence |
denotes |
TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans. |
| TextSentencer_T2 |
126-193 |
Sentence |
denotes |
CD44 and sulfation have both been implicated in leukocyte adhesion. |
| T2 |
126-193 |
Sentence |
denotes |
CD44 and sulfation have both been implicated in leukocyte adhesion. |
| T2 |
126-193 |
Sentence |
denotes |
CD44 and sulfation have both been implicated in leukocyte adhesion. |
| TextSentencer_T3 |
194-373 |
Sentence |
denotes |
In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events. |
| T3 |
194-373 |
Sentence |
denotes |
In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events. |
| T3 |
194-373 |
Sentence |
denotes |
In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events. |
| TextSentencer_T4 |
374-470 |
Sentence |
denotes |
However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines. |
| T4 |
374-470 |
Sentence |
denotes |
However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines. |
| T4 |
374-470 |
Sentence |
denotes |
However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines. |
| TextSentencer_T5 |
471-543 |
Sentence |
denotes |
We determined that TNF-alpha induces the carbohydrate sulfation of CD44. |
| T5 |
471-543 |
Sentence |
denotes |
We determined that TNF-alpha induces the carbohydrate sulfation of CD44. |
| T5 |
471-543 |
Sentence |
denotes |
We determined that TNF-alpha induces the carbohydrate sulfation of CD44. |
| TextSentencer_T6 |
544-623 |
Sentence |
denotes |
CD44 was established as a major sulfated cell surface protein on myeloid cells. |
| T6 |
544-623 |
Sentence |
denotes |
CD44 was established as a major sulfated cell surface protein on myeloid cells. |
| T6 |
544-623 |
Sentence |
denotes |
CD44 was established as a major sulfated cell surface protein on myeloid cells. |
| TextSentencer_T7 |
624-746 |
Sentence |
denotes |
In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate. |
| T7 |
624-746 |
Sentence |
denotes |
In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate. |
| T7 |
624-746 |
Sentence |
denotes |
In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate. |
| TextSentencer_T8 |
747-903 |
Sentence |
denotes |
However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44. |
| T8 |
747-903 |
Sentence |
denotes |
However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44. |
| T8 |
747-903 |
Sentence |
denotes |
However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44. |
| TextSentencer_T9 |
904-1056 |
Sentence |
denotes |
Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation. |
| T9 |
904-1056 |
Sentence |
denotes |
Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation. |
| T9 |
904-1056 |
Sentence |
denotes |
Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation. |
| TextSentencer_T10 |
1057-1242 |
Sentence |
denotes |
Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment. |
| T10 |
1057-1242 |
Sentence |
denotes |
Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment. |
| T10 |
1057-1242 |
Sentence |
denotes |
Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment. |
| TextSentencer_T11 |
1243-1364 |
Sentence |
denotes |
This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44. |
| T11 |
1243-1364 |
Sentence |
denotes |
This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44. |
| T11 |
1243-1364 |
Sentence |
denotes |
This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44. |
| TextSentencer_T12 |
1365-1545 |
Sentence |
denotes |
This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44. |
| T12 |
1365-1545 |
Sentence |
denotes |
This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44. |
| T12 |
1365-1545 |
Sentence |
denotes |
This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44. |
| TextSentencer_T13 |
1546-1705 |
Sentence |
denotes |
In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells. |
| T13 |
1546-1705 |
Sentence |
denotes |
In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells. |
| T13 |
1546-1705 |
Sentence |
denotes |
In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells. |