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PubMed:11853019 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-136 Sentence denotes Decreased expression of hippocampal cholinergic neurostimulating peptide precursor protein mRNA in the hippocampus in Alzheimer disease.
T1 0-136 Sentence denotes Decreased expression of hippocampal cholinergic neurostimulating peptide precursor protein mRNA in the hippocampus in Alzheimer disease.
TextSentencer_T2 137-266 Sentence denotes Hippocampal cholinergic neurostimulating peptide (HCNP) is involved in the phenotype development of the septo-hippocampal system.
T2 137-266 Sentence denotes Hippocampal cholinergic neurostimulating peptide (HCNP) is involved in the phenotype development of the septo-hippocampal system.
TextSentencer_T3 267-491 Sentence denotes HCNP precursor protein (HCNP-pp) is known to interact with other molecules including phosphatidylethanolamine and Raf-1 kinase, and is also known as phosphatidylethanolamine-binding protein and raf kinase-inhibitory protein.
T3 267-491 Sentence denotes HCNP precursor protein (HCNP-pp) is known to interact with other molecules including phosphatidylethanolamine and Raf-1 kinase, and is also known as phosphatidylethanolamine-binding protein and raf kinase-inhibitory protein.
TextSentencer_T4 492-780 Sentence denotes To assess whether HCNP-pp is involved in the pathogenesis of Alzheimer disease (AD), the expression levels of its mRNA in the hippocampus of autopsy brains from patients with dementia (including AD and ischemic vascular dementia) were compared with those of non-demented control subjects.
T4 492-780 Sentence denotes To assess whether HCNP-pp is involved in the pathogenesis of Alzheimer disease (AD), the expression levels of its mRNA in the hippocampus of autopsy brains from patients with dementia (including AD and ischemic vascular dementia) were compared with those of non-demented control subjects.
TextSentencer_T5 781-993 Sentence denotes The in situ hybridization analysis revealed that the expression of HCNP-pp mRNA in patients with clinically late-onset AD was decreased in the hippocampal CA1 field, but not in the CA3 field or the dentate gyrus.
T5 781-993 Sentence denotes The in situ hybridization analysis revealed that the expression of HCNP-pp mRNA in patients with clinically late-onset AD was decreased in the hippocampal CA1 field, but not in the CA3 field or the dentate gyrus.
TextSentencer_T6 994-1094 Sentence denotes The early-onset AD patients showed a wide range of expression levels in the hippocampal sub-regions.
T6 994-1094 Sentence denotes The early-onset AD patients showed a wide range of expression levels in the hippocampal sub-regions.
TextSentencer_T7 1095-1179 Sentence denotes Northern blot analysis of HCNP-pp mRNA in brain tissue supported these observations.
T7 1095-1179 Sentence denotes Northern blot analysis of HCNP-pp mRNA in brain tissue supported these observations.
TextSentencer_T8 1180-1471 Sentence denotes Since HCNP is known to stimulate the enzymatic activity of choline acetyltransferase in neurons, its low expression in the CAI field of AD patients may explain the downregulation of cholinergic neurons seen in these patients and may thus contribute to the pathogenic processes underlying AD.
T8 1180-1471 Sentence denotes Since HCNP is known to stimulate the enzymatic activity of choline acetyltransferase in neurons, its low expression in the CAI field of AD patients may explain the downregulation of cholinergic neurons seen in these patients and may thus contribute to the pathogenic processes underlying AD.