> top > projects > sentences > docs > PubMed:11703582 > annotations
sentences Home  

PubMed:11703582 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-88 Sentence denotes Renal amyloidosis caused by a novel stop-codon mutation in the apolipoprotein A-II gene.
T1 0-88 Sentence denotes Renal amyloidosis caused by a novel stop-codon mutation in the apolipoprotein A-II gene.
TextSentencer_T2 89-100 Sentence denotes BACKGROUND:
T2 89-100 Sentence denotes BACKGROUND:
TextSentencer_T3 101-407 Sentence denotes Although apolipoprotein A-II (apoA-II) associated amyloidosis has been described in the senescent accelerated mouse (SAM) model of aging, so far there has been no report of human apoA-II amyloidosis except for a recent report of renal amyloidosis resulting from a stop-codon to glycine mutation of apoA-II.
T3 101-407 Sentence denotes Although apolipoprotein A-II (apoA-II) associated amyloidosis has been described in the senescent accelerated mouse (SAM) model of aging, so far there has been no report of human apoA-II amyloidosis except for a recent report of renal amyloidosis resulting from a stop-codon to glycine mutation of apoA-II.
TextSentencer_T4 408-487 Sentence denotes The mechanisms of amyloid formation in human apoA-II amyloidosis are not clear.
T4 408-487 Sentence denotes The mechanisms of amyloid formation in human apoA-II amyloidosis are not clear.
TextSentencer_T5 488-496 Sentence denotes METHODS:
T5 488-496 Sentence denotes METHODS:
TextSentencer_T6 497-580 Sentence denotes A 46-year-old Caucasian male with proteinuria noted at 42 years of age was studied.
T6 497-580 Sentence denotes A 46-year-old Caucasian male with proteinuria noted at 42 years of age was studied.
TextSentencer_T7 581-635 Sentence denotes Renal biopsy revealed amyloid deposition in glomeruli.
T7 581-635 Sentence denotes Renal biopsy revealed amyloid deposition in glomeruli.
TextSentencer_T8 636-741 Sentence denotes DNA analysis of genes known to be associated with hereditary renal amyloidosis revealed no abnormalities.
T8 636-741 Sentence denotes DNA analysis of genes known to be associated with hereditary renal amyloidosis revealed no abnormalities.
TextSentencer_T9 742-830 Sentence denotes To elucidate the type of his amyloidosis, apoA-II gene and plasma apoA-II were examined.
T9 742-830 Sentence denotes To elucidate the type of his amyloidosis, apoA-II gene and plasma apoA-II were examined.
TextSentencer_T10 831-1014 Sentence denotes RESULTS: DNA analysis revealed heterozygosity for a G to C transversion at the second position of the stop-codon of apoA-II gene, suggesting a stop to serine substitution at codon 78.
T10 831-1014 Sentence denotes RESULTS: DNA analysis revealed heterozygosity for a G to C transversion at the second position of the stop-codon of apoA-II gene, suggesting a stop to serine substitution at codon 78.
TextSentencer_T11 1015-1206 Sentence denotes Western blot analysis and amino acid sequence analysis of the patient's plasma apoA-II showed both normal apoA-II and variant apoA-II with a 21-amino acid residue extension at the C-terminus.
T11 1015-1206 Sentence denotes Western blot analysis and amino acid sequence analysis of the patient's plasma apoA-II showed both normal apoA-II and variant apoA-II with a 21-amino acid residue extension at the C-terminus.
TextSentencer_T12 1207-1219 Sentence denotes CONCLUSIONS:
T12 1207-1219 Sentence denotes CONCLUSIONS:
TextSentencer_T13 1220-1421 Sentence denotes These results indicate that the patient's amyloid fibrils were derived from apoA-II and the amyloidogenesis is likely to be closely linked to the peptide extension at the C-terminus of variant apoA-II.
T13 1220-1421 Sentence denotes These results indicate that the patient's amyloid fibrils were derived from apoA-II and the amyloidogenesis is likely to be closely linked to the peptide extension at the C-terminus of variant apoA-II.
TextSentencer_T14 1422-1498 Sentence denotes The pathogenesis of human apoA-II amyloidosis is different from that of SAM.
T14 1422-1498 Sentence denotes The pathogenesis of human apoA-II amyloidosis is different from that of SAM.