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PubMed:11447138 JSONTXT 58 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-142 Sentence denotes Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44.
T1 0-142 Sentence denotes Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44.
T1 0-142 Sentence denotes Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44.
TextSentencer_T2 143-318 Sentence denotes Increased mucosal expression of TF, the Thomsen-Friedenreich oncofetal blood group antigen (galactose beta1-3 N-acetylgalactosamine alpha-) occurs in colon cancer and colitis.
T2 143-318 Sentence denotes Increased mucosal expression of TF, the Thomsen-Friedenreich oncofetal blood group antigen (galactose beta1-3 N-acetylgalactosamine alpha-) occurs in colon cancer and colitis.
T2 143-318 Sentence denotes Increased mucosal expression of TF, the Thomsen-Friedenreich oncofetal blood group antigen (galactose beta1-3 N-acetylgalactosamine alpha-) occurs in colon cancer and colitis.
TextSentencer_T3 319-444 Sentence denotes This allows binding of TF-specific lectins, such as peanut agglutinin (PNA), which is mitogenic to the colorectal epithelium.
T3 319-444 Sentence denotes This allows binding of TF-specific lectins, such as peanut agglutinin (PNA), which is mitogenic to the colorectal epithelium.
T3 319-444 Sentence denotes This allows binding of TF-specific lectins, such as peanut agglutinin (PNA), which is mitogenic to the colorectal epithelium.
TextSentencer_T4 445-647 Sentence denotes To identify the cell surface TF-expressing glycoprotein(s), HT29 and Caco2 colon cancer cells were surface-labeled with Na[(125)I] and subjected to PNA-agarose affinity purification and electrophoresis.
T4 445-647 Sentence denotes To identify the cell surface TF-expressing glycoprotein(s), HT29 and Caco2 colon cancer cells were surface-labeled with Na[(125)I] and subjected to PNA-agarose affinity purification and electrophoresis.
T4 445-647 Sentence denotes To identify the cell surface TF-expressing glycoprotein(s), HT29 and Caco2 colon cancer cells were surface-labeled with Na[(125)I] and subjected to PNA-agarose affinity purification and electrophoresis.
TextSentencer_T5 648-808 Sentence denotes Proteins, approximately 110-180 kDa, present in HT29 but not Caco2 were identified by Western blotting as high molecular weight splice variants of CD44 (CD44v).
T5 648-808 Sentence denotes Proteins, approximately 110-180 kDa, present in HT29 but not Caco2 were identified by Western blotting as high molecular weight splice variants of CD44 (CD44v).
T5 648-808 Sentence denotes Proteins, approximately 110-180 kDa, present in HT29 but not Caco2 were identified by Western blotting as high molecular weight splice variants of CD44 (CD44v).
TextSentencer_T6 809-949 Sentence denotes Selective removal of TF antigen by Streptococcus pneumoniae endo-alpha-N-acetylgalactosaminidase substantially reduced PNA binding to CD44v.
T6 809-949 Sentence denotes Selective removal of TF antigen by Streptococcus pneumoniae endo-alpha-N-acetylgalactosaminidase substantially reduced PNA binding to CD44v.
T6 809-949 Sentence denotes Selective removal of TF antigen by Streptococcus pneumoniae endo-alpha-N-acetylgalactosaminidase substantially reduced PNA binding to CD44v.
TextSentencer_T7 950-1065 Sentence denotes Immunoprecipitated CD44v from HT29 cell extracts also expressed sialyl-Tn (sialyl 2-6 N-acetylgalactosaminealpha-).
T7 950-1065 Sentence denotes Immunoprecipitated CD44v from HT29 cell extracts also expressed sialyl-Tn (sialyl 2-6 N-acetylgalactosaminealpha-).
T7 950-1065 Sentence denotes Immunoprecipitated CD44v from HT29 cell extracts also expressed sialyl-Tn (sialyl 2-6 N-acetylgalactosaminealpha-).
TextSentencer_T8 1066-1190 Sentence denotes Incubation of PNA 15 microg/ml with HT29 cells caused no additional proliferative effect in the presence of anti-CD44v6 mAb.
T8 1066-1190 Sentence denotes Incubation of PNA 15 microg/ml with HT29 cells caused no additional proliferative effect in the presence of anti-CD44v6 mAb.
T8 1066-1190 Sentence denotes Incubation of PNA 15 microg/ml with HT29 cells caused no additional proliferative effect in the presence of anti-CD44v6 mAb.
TextSentencer_T9 1191-1275 Sentence denotes In colon cancer tissue extracts (N = 3) PNA bound to CD44v but not to standard CD44.
T9 1191-1275 Sentence denotes In colon cancer tissue extracts (N = 3) PNA bound to CD44v but not to standard CD44.
T9 1191-1275 Sentence denotes In colon cancer tissue extracts (N = 3) PNA bound to CD44v but not to standard CD44.
TextSentencer_T10 1276-1361 Sentence denotes These data show that CD44v is a major PNA-binding glycoprotein in colon cancer cells.
T10 1276-1361 Sentence denotes These data show that CD44v is a major PNA-binding glycoprotein in colon cancer cells.
T10 1276-1361 Sentence denotes These data show that CD44v is a major PNA-binding glycoprotein in colon cancer cells.
TextSentencer_T11 1362-1621 Sentence denotes Because CD44 high molecular weight splice variants are present in colon cancer and inflammatory bowel disease tissue but are absent from normal mucosa, these results may also explain the increased PNA reactivity in colon cancer and inflammatory bowel disease.
T11 1362-1621 Sentence denotes Because CD44 high molecular weight splice variants are present in colon cancer and inflammatory bowel disease tissue but are absent from normal mucosa, these results may also explain the increased PNA reactivity in colon cancer and inflammatory bowel disease.
T11 1362-1621 Sentence denotes Because CD44 high molecular weight splice variants are present in colon cancer and inflammatory bowel disease tissue but are absent from normal mucosa, these results may also explain the increased PNA reactivity in colon cancer and inflammatory bowel disease.
TextSentencer_T12 1622-1861 Sentence denotes The coexpression of oncofetal carbohydrate antigens TF and sialyl-Tn on CD44 splice variants provides a link between cancer-associated changes in glycosylation and CD44 splicing, both of which correlate with increased metastatic potential.
T12 1622-1861 Sentence denotes The coexpression of oncofetal carbohydrate antigens TF and sialyl-Tn on CD44 splice variants provides a link between cancer-associated changes in glycosylation and CD44 splicing, both of which correlate with increased metastatic potential.
T12 1622-1861 Sentence denotes The coexpression of oncofetal carbohydrate antigens TF and sialyl-Tn on CD44 splice variants provides a link between cancer-associated changes in glycosylation and CD44 splicing, both of which correlate with increased metastatic potential.