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PubMed:11421356 JSONTXT 59 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-90 Sentence denotes Safe as mother's milk: carbohydrates as future anti-adhesion drugs for bacterial diseases.
T1 0-90 Sentence denotes Safe as mother's milk: carbohydrates as future anti-adhesion drugs for bacterial diseases.
TextSentencer_T2 91-204 Sentence denotes The majority of infectious diseases are initiated by adhesion of pathogenic organisms to the tissues of the host.
T2 91-204 Sentence denotes The majority of infectious diseases are initiated by adhesion of pathogenic organisms to the tissues of the host.
TextSentencer_T3 205-383 Sentence denotes In many cases, this adhesion is mediated by lectins present on the surface of the infectious organism that bind to complementary carbohydrates on the surface of the host tissues.
T3 205-383 Sentence denotes In many cases, this adhesion is mediated by lectins present on the surface of the infectious organism that bind to complementary carbohydrates on the surface of the host tissues.
TextSentencer_T4 384-450 Sentence denotes Lectin-deficient mutants often lack ability to initiate infection.
T4 384-450 Sentence denotes Lectin-deficient mutants often lack ability to initiate infection.
TextSentencer_T5 451-569 Sentence denotes Soluble carbohydrates recognized by the bacterial lectins block the adhesion of the bacteria to animal cells in vitro.
T5 451-569 Sentence denotes Soluble carbohydrates recognized by the bacterial lectins block the adhesion of the bacteria to animal cells in vitro.
TextSentencer_T6 570-749 Sentence denotes Moreover, they have also been shown to protect against experimental infection by lectin-carrying bacteria in different organs of mammals such as mice, rabbits, calves and monkeys.
T6 570-749 Sentence denotes Moreover, they have also been shown to protect against experimental infection by lectin-carrying bacteria in different organs of mammals such as mice, rabbits, calves and monkeys.
TextSentencer_T7 750-1023 Sentence denotes In a phase II clinical trial, a pentasaccharide shown to have anti-adhesive activity against Streptococcus pneumoniae and Hemophilus influenzae in vitro failed to protect young children from nasopharyngeal colonization with these organisms and from developing otitis media.
T7 750-1023 Sentence denotes In a phase II clinical trial, a pentasaccharide shown to have anti-adhesive activity against Streptococcus pneumoniae and Hemophilus influenzae in vitro failed to protect young children from nasopharyngeal colonization with these organisms and from developing otitis media.
TextSentencer_T8 1024-1291 Sentence denotes This could be because insufficient drug was delivered via nasal spray, because bacteria express multiple specificities, the inhibition of which may require a cocktail of oligosaccharides, or because children have different carbohydrate receptors from those of adults.
T8 1024-1291 Sentence denotes This could be because insufficient drug was delivered via nasal spray, because bacteria express multiple specificities, the inhibition of which may require a cocktail of oligosaccharides, or because children have different carbohydrate receptors from those of adults.
TextSentencer_T9 1292-1520 Sentence denotes The results of a clinical trial in which N-acetylneuraminyl(alpha2-3)lactose was administered orally to Helicobacter pylori positive patients in an effort to reduce or eradicate bacterial colonization, are awaited with interest.
T9 1292-1520 Sentence denotes The results of a clinical trial in which N-acetylneuraminyl(alpha2-3)lactose was administered orally to Helicobacter pylori positive patients in an effort to reduce or eradicate bacterial colonization, are awaited with interest.
TextSentencer_T10 1521-1763 Sentence denotes Although the high cost of production of the required oligosaccharides is falling with the recent introduction of enzymatic methods of synthesis, new technologies, in particular the use of engineered bacteria, promise to lower it even further.
T10 1521-1763 Sentence denotes Although the high cost of production of the required oligosaccharides is falling with the recent introduction of enzymatic methods of synthesis, new technologies, in particular the use of engineered bacteria, promise to lower it even further.
TextSentencer_T11 1764-1894 Sentence denotes Attachment of the oligosaccharides to soluble polymeric carriers will increase greatly their effectiveness as antiadhesion agents.
T11 1764-1894 Sentence denotes Attachment of the oligosaccharides to soluble polymeric carriers will increase greatly their effectiveness as antiadhesion agents.
TextSentencer_T12 1895-2037 Sentence denotes There is no doubt that anti-adhesive oligosaccharides will in the near future join the arsenal of drugs for the therapy of bacterial diseases.
T12 1895-2037 Sentence denotes There is no doubt that anti-adhesive oligosaccharides will in the near future join the arsenal of drugs for the therapy of bacterial diseases.