| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-109 |
Sentence |
denotes |
Enhanced expression of a-series gangliosides in fibroblasts of patients with peroxisome biogenesis disorders. |
| T1 |
0-109 |
Sentence |
denotes |
Enhanced expression of a-series gangliosides in fibroblasts of patients with peroxisome biogenesis disorders. |
| TextSentencer_T2 |
110-258 |
Sentence |
denotes |
Peroxisome biogenesis disorders (PBD) are classified into Zellweger syndrome (ZS), infantile Refsum disease (IRD) and neonatal adrenoleukodystrophy. |
| T2 |
110-258 |
Sentence |
denotes |
Peroxisome biogenesis disorders (PBD) are classified into Zellweger syndrome (ZS), infantile Refsum disease (IRD) and neonatal adrenoleukodystrophy. |
| TextSentencer_T3 |
259-362 |
Sentence |
denotes |
Disturbances in the differentiation of neural cells such as migration arrest are characteristic of PBD. |
| T3 |
259-362 |
Sentence |
denotes |
Disturbances in the differentiation of neural cells such as migration arrest are characteristic of PBD. |
| TextSentencer_T4 |
363-435 |
Sentence |
denotes |
So far the pathogenesis of these disturbances is not clearly understood. |
| T4 |
363-435 |
Sentence |
denotes |
So far the pathogenesis of these disturbances is not clearly understood. |
| TextSentencer_T5 |
436-535 |
Sentence |
denotes |
We describe an altered metabolism of glycosphingolipids in PBD which has not yet been investigated. |
| T5 |
436-535 |
Sentence |
denotes |
We describe an altered metabolism of glycosphingolipids in PBD which has not yet been investigated. |
| TextSentencer_T6 |
536-660 |
Sentence |
denotes |
We observed an increased amount of a-series gangliosides, GM2, GM1 and GD1a, in the fibroblasts of patients with ZS and IRD. |
| T6 |
536-660 |
Sentence |
denotes |
We observed an increased amount of a-series gangliosides, GM2, GM1 and GD1a, in the fibroblasts of patients with ZS and IRD. |
| TextSentencer_T7 |
661-745 |
Sentence |
denotes |
Gangliosides GM1 and GD1a were not present in detectable amounts in normal subjects. |
| T7 |
661-745 |
Sentence |
denotes |
Gangliosides GM1 and GD1a were not present in detectable amounts in normal subjects. |
| TextSentencer_T8 |
746-920 |
Sentence |
denotes |
A key step in the synthesis of a-series gangliosides is a transfer of GalNAc to ganglioside GM3, so we determined the level of ganglioside GM3 by immunohistochemical methods. |
| T8 |
746-920 |
Sentence |
denotes |
A key step in the synthesis of a-series gangliosides is a transfer of GalNAc to ganglioside GM3, so we determined the level of ganglioside GM3 by immunohistochemical methods. |
| TextSentencer_T9 |
921-1054 |
Sentence |
denotes |
We found a granular structure, which was positive toward anti-ganglioside GM3 antibody in the cytoplasm of the patients' fibroblasts. |
| T9 |
921-1054 |
Sentence |
denotes |
We found a granular structure, which was positive toward anti-ganglioside GM3 antibody in the cytoplasm of the patients' fibroblasts. |
| TextSentencer_T10 |
1055-1138 |
Sentence |
denotes |
In control cells, the cell membrane was slightly positive toward anti-GM3 antibody. |
| T10 |
1055-1138 |
Sentence |
denotes |
In control cells, the cell membrane was slightly positive toward anti-GM3 antibody. |
| TextSentencer_T11 |
1139-1309 |
Sentence |
denotes |
These results may help to clarify the pathogenesis of PBD with respect to the functional roles of glycosphingolipids in cell differentiation, proliferation and apoptosis. |
| T11 |
1139-1309 |
Sentence |
denotes |
These results may help to clarify the pathogenesis of PBD with respect to the functional roles of glycosphingolipids in cell differentiation, proliferation and apoptosis. |