> top > projects > sentences > docs > PubMed:11261840 > annotations
sentences Home  

PubMed:11261840 JSONTXT 25 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-132 Sentence denotes Modulation of the basal activity of phosphatidylinositol-3-kinase/protein kinase B signaling pathway in human hepatocarcinoma cells.
T1 0-132 Sentence denotes Modulation of the basal activity of phosphatidylinositol-3-kinase/protein kinase B signaling pathway in human hepatocarcinoma cells.
TextSentencer_T2 133-263 Sentence denotes The modulation of GnT-V activity by signaling molecules in PI-3-K/PKB pathway in human hepatocarcinoma cell line 7721 was studied.
T2 133-263 Sentence denotes The modulation of GnT-V activity by signaling molecules in PI-3-K/PKB pathway in human hepatocarcinoma cell line 7721 was studied.
TextSentencer_T3 264-491 Sentence denotes GnT-V activity was determined after the transfection of sense or antisense cDNA of PKB into the cells, as well as the addition of activators, specific inhibitors, and the antibodies to the enzyme assay system or culture medium.
T3 264-491 Sentence denotes GnT-V activity was determined after the transfection of sense or antisense cDNA of PKB into the cells, as well as the addition of activators, specific inhibitors, and the antibodies to the enzyme assay system or culture medium.
TextSentencer_T4 492-644 Sentence denotes It was found that the basal activity of GnT-V was up regulated by the sense and down regulated by the antisense cDNA of PKB transfected into 7721 cells.
T4 492-644 Sentence denotes It was found that the basal activity of GnT-V was up regulated by the sense and down regulated by the antisense cDNA of PKB transfected into 7721 cells.
TextSentencer_T5 645-882 Sentence denotes GnT-V was activated by PIP2, PIP3 or GTPgamma[S] added to the assay system, and the activation of PIP2 or GTPgamma[S] was abolished by LY2940002, a specific inhibitor of PI-3-K, but the activation of PIP3 was not attenuated by LY2940002.
T5 645-882 Sentence denotes GnT-V was activated by PIP2, PIP3 or GTPgamma[S] added to the assay system, and the activation of PIP2 or GTPgamma[S] was abolished by LY2940002, a specific inhibitor of PI-3-K, but the activation of PIP3 was not attenuated by LY2940002.
TextSentencer_T6 883-1011 Sentence denotes In addition, GnT-V activity in cultured parental or H-ras transfected cells was inhibited by the antibody against PKB or PI-3-K.
T6 883-1011 Sentence denotes In addition, GnT-V activity in cultured parental or H-ras transfected cells was inhibited by the antibody against PKB or PI-3-K.
TextSentencer_T7 1012-1115 Sentence denotes These findings demonstrated the involvement of PI-3-K/PKB signaling pathway in the regulation of GnT-V.
T7 1012-1115 Sentence denotes These findings demonstrated the involvement of PI-3-K/PKB signaling pathway in the regulation of GnT-V.
TextSentencer_T8 1116-1348 Sentence denotes Moreover, ET18-OCH3, an inhibitor of Raf translocation and PI-PLC enzyme, which produces the activator of PKC, as well as the antibodies against Raf-1 or MEK also inhibited GnT-V activity in the parental and H-ras transfected cells.
T8 1116-1348 Sentence denotes Moreover, ET18-OCH3, an inhibitor of Raf translocation and PI-PLC enzyme, which produces the activator of PKC, as well as the antibodies against Raf-1 or MEK also inhibited GnT-V activity in the parental and H-ras transfected cells.
TextSentencer_T9 1349-1448 Sentence denotes The inhibitory rates, however, were less in the transfected cells than those in the parental cells.
T9 1349-1448 Sentence denotes The inhibitory rates, however, were less in the transfected cells than those in the parental cells.
TextSentencer_T10 1449-1645 Sentence denotes These results reveal that in parental and H-ras transfected 7721 cells, the basal activity of GnT-V is also regulated by the Ras/Raf-1/MEK/MAPK cascade in addition to PI-3-K/PKB signaling pathway.
T10 1449-1645 Sentence denotes These results reveal that in parental and H-ras transfected 7721 cells, the basal activity of GnT-V is also regulated by the Ras/Raf-1/MEK/MAPK cascade in addition to PI-3-K/PKB signaling pathway.
TextSentencer_T11 1646-1857 Sentence denotes The significance of these two pathways in the regulation of GnT-V and their relations to the activation of PKC previously reported by our laboratory (Ju TZ et al., 1995 Glyconjugate J 12, 767-772) was discussed.
T11 1646-1857 Sentence denotes The significance of these two pathways in the regulation of GnT-V and their relations to the activation of PKC previously reported by our laboratory (Ju TZ et al., 1995 Glyconjugate J 12, 767-772) was discussed.