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PubMed:11133022 JSONTXT 39 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-124 Sentence denotes Globotriaosyl ceramide modulates interferon-alpha-induced growth inhibition and CD19 expression in Burkitt's lymphoma cells.
T1 0-124 Sentence denotes Globotriaosyl ceramide modulates interferon-alpha-induced growth inhibition and CD19 expression in Burkitt's lymphoma cells.
TextSentencer_T2 125-337 Sentence denotes Previous studies have indicated that globotriaosyl ceramide (Gb3 or CD77) plays a role in alpha-interferon signal transduction and CD19-mediated homotypic adhesion in B cell lines derived from Burkitt's lymphoma.
T2 125-337 Sentence denotes Previous studies have indicated that globotriaosyl ceramide (Gb3 or CD77) plays a role in alpha-interferon signal transduction and CD19-mediated homotypic adhesion in B cell lines derived from Burkitt's lymphoma.
TextSentencer_T3 338-621 Sentence denotes These roles for Gb3 may involve the proteins IFNAR-1 (subunit 1 of the interferon-alpha receptor) and CD19, respectively, both of which have potential Gb3-binding sites in their extracellular domains which resemble those of the verotoxin (Shiga toxin and Shiga-like toxin) B subunit.
T3 338-621 Sentence denotes These roles for Gb3 may involve the proteins IFNAR-1 (subunit 1 of the interferon-alpha receptor) and CD19, respectively, both of which have potential Gb3-binding sites in their extracellular domains which resemble those of the verotoxin (Shiga toxin and Shiga-like toxin) B subunit.
TextSentencer_T4 622-742 Sentence denotes The majority of this work was performed using wild-type Daudi cells and a single, Gb3-deficient mutant cell line, VT500.
T4 622-742 Sentence denotes The majority of this work was performed using wild-type Daudi cells and a single, Gb3-deficient mutant cell line, VT500.
TextSentencer_T5 743-962 Sentence denotes In the present investigations, these and additional Daudi-derived cells with varying degrees of sensitivity to interferon-alpha were examined for Gb3 expression, interferon-induced growth inhibition and CD19 expression.
T5 743-962 Sentence denotes In the present investigations, these and additional Daudi-derived cells with varying degrees of sensitivity to interferon-alpha were examined for Gb3 expression, interferon-induced growth inhibition and CD19 expression.
TextSentencer_T6 963-1098 Sentence denotes The degree of interferon-induced growth inhibition and CD19 expression correlated with Gb3 expression in the various cell lines tested.
T6 963-1098 Sentence denotes The degree of interferon-induced growth inhibition and CD19 expression correlated with Gb3 expression in the various cell lines tested.
TextSentencer_T7 1099-1262 Sentence denotes In addition, reconstitution of the VT500 cell line with Gb3 but not other glycolipids partially restored the sensitivity of cells to IFN-induced growth inhibition.
T7 1099-1262 Sentence denotes In addition, reconstitution of the VT500 cell line with Gb3 but not other glycolipids partially restored the sensitivity of cells to IFN-induced growth inhibition.
TextSentencer_T8 1263-1470 Sentence denotes The degree to which reconstitution restored sensitivity to growth inhibition was similar to the results of previous studies in which Gb3 reconstitution restored sensitivity to verotoxin-induced cytotoxicity.
T8 1263-1470 Sentence denotes The degree to which reconstitution restored sensitivity to growth inhibition was similar to the results of previous studies in which Gb3 reconstitution restored sensitivity to verotoxin-induced cytotoxicity.
TextSentencer_T9 1471-1674 Sentence denotes These results demonstrate that Gb3 is specifically required for IFN-induced growth inhibition in Daudi cells and provide further evidence of a role for Gb3 in CD19 expression and function in these cells.
T9 1471-1674 Sentence denotes These results demonstrate that Gb3 is specifically required for IFN-induced growth inhibition in Daudi cells and provide further evidence of a role for Gb3 in CD19 expression and function in these cells.