| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-59 |
Sentence |
denotes |
Transfer of iron-sulfur cluster from NifU to apoferredoxin. |
| T2 |
60-271 |
Sentence |
denotes |
Iron-sulfur proteins are present in a wide variety of organisms and are known to play important physiological roles, not only in electron transfer and metabolic reactions, but also in transcriptional regulation. |
| T3 |
272-389 |
Sentence |
denotes |
However, little is known about how iron-sulfur clusters themselves are synthesized and assembled within polypeptides. |
| T4 |
390-635 |
Sentence |
denotes |
Here we show that a [2Fe-2S] cluster-containing NifU of cyanobacterium Synechocystis PCC6803, SyNifU, possesses the ability to deliver its [2Fe-2S] cluster to an apoferredoxin without the aid of other proteinaceous or nonproteinaceous factor(s). |
| T5 |
636-718 |
Sentence |
denotes |
Upon delivery the reconstituted holoferredoxin regained electron transfer ability. |
| T6 |
719-898 |
Sentence |
denotes |
The [2Fe-2S] cluster contained within SyNifU was labile upon exposure to the iron-chelating reagent EDTA, suggesting that the iron-sulfur cluster is abnormally exposed to solvent. |
| T7 |
899-1035 |
Sentence |
denotes |
We propose that NifU serves as a scaffold for iron-sulfur cluster assembly and functions as a mediator for iron-sulfur cluster delivery. |
