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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-124 Sentence denotes Arginine-rich anti-vascular endothelial growth factor peptides inhibit tumor growth and metastasis by blocking angiogenesis.
T1 0-124 Sentence denotes Arginine-rich anti-vascular endothelial growth factor peptides inhibit tumor growth and metastasis by blocking angiogenesis.
TextSentencer_T2 125-209 Sentence denotes Tumor angiogenesis is a critical step for the growth and metastasis of solid tumors.
T2 125-209 Sentence denotes Tumor angiogenesis is a critical step for the growth and metastasis of solid tumors.
TextSentencer_T3 210-378 Sentence denotes Vascular endothelial growth factor (VEGF) is a specific and potent angiogenic factor and contributes to the development of solid tumors by promoting tumor angiogenesis.
T3 210-378 Sentence denotes Vascular endothelial growth factor (VEGF) is a specific and potent angiogenic factor and contributes to the development of solid tumors by promoting tumor angiogenesis.
TextSentencer_T4 379-482 Sentence denotes Therefore, it is a prime therapeutic target for the development of antagonists for treatment of cancer.
T4 379-482 Sentence denotes Therefore, it is a prime therapeutic target for the development of antagonists for treatment of cancer.
TextSentencer_T5 483-634 Sentence denotes We identified from peptide libraries arginine-rich hexapeptides that inhibit the interaction of VEGF(165) with VEGF receptor (IC(50) = 2-4 micrometer).
T5 483-634 Sentence denotes We identified from peptide libraries arginine-rich hexapeptides that inhibit the interaction of VEGF(165) with VEGF receptor (IC(50) = 2-4 micrometer).
TextSentencer_T6 635-721 Sentence denotes They have no effect on binding of basic fibroblast growth factor to cellular receptor.
T6 635-721 Sentence denotes They have no effect on binding of basic fibroblast growth factor to cellular receptor.
TextSentencer_T7 722-845 Sentence denotes The hexapeptides inhibit the proliferation of human umbilical vein endothelial cells induced by VEGF(165) without toxicity.
T7 722-845 Sentence denotes The hexapeptides inhibit the proliferation of human umbilical vein endothelial cells induced by VEGF(165) without toxicity.
TextSentencer_T8 846-1053 Sentence denotes The peptides bind to VEGF and inhibit binding of both VEGF(165) and VEGF(121), suggesting that the peptides interact with the main body of VEGF but not the heparin-binding domain that is absent in VEGF(121).
T8 846-1053 Sentence denotes The peptides bind to VEGF and inhibit binding of both VEGF(165) and VEGF(121), suggesting that the peptides interact with the main body of VEGF but not the heparin-binding domain that is absent in VEGF(121).
TextSentencer_T9 1054-1190 Sentence denotes The identified peptides block the angiogenesis induced by VEGF(165) in vivo in the chick chorioallantoic membrane and the rabbit cornea.
T9 1054-1190 Sentence denotes The identified peptides block the angiogenesis induced by VEGF(165) in vivo in the chick chorioallantoic membrane and the rabbit cornea.
TextSentencer_T10 1191-1333 Sentence denotes Furthermore, one of the hexapeptides, RRKRRR, blocks the growth and metastasis of VEGF-secreting HM7 human colon carcinoma cells in nude mice.
T10 1191-1333 Sentence denotes Furthermore, one of the hexapeptides, RRKRRR, blocks the growth and metastasis of VEGF-secreting HM7 human colon carcinoma cells in nude mice.
TextSentencer_T11 1334-1597 Sentence denotes Based on our results, the arginine-rich hexapeptides may be effective for the treatment of various human tumors and other angiogenesis-dependent diseases that are related to the action of VEGF and could also serve as leads for development of more effective drugs.
T11 1334-1597 Sentence denotes Based on our results, the arginine-rich hexapeptides may be effective for the treatment of various human tumors and other angiogenesis-dependent diseases that are related to the action of VEGF and could also serve as leads for development of more effective drugs.