| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-149 |
Sentence |
denotes |
The influence of glucan polymer structure and solution conformation on binding to (1-->3)-beta-D-glucan receptors in a human monocyte-like cell line. |
| T1 |
0-149 |
Sentence |
denotes |
The influence of glucan polymer structure and solution conformation on binding to (1-->3)-beta-D-glucan receptors in a human monocyte-like cell line. |
| T1 |
0-149 |
Sentence |
denotes |
The influence of glucan polymer structure and solution conformation on binding to (1-->3)-beta-D-glucan receptors in a human monocyte-like cell line. |
| TextSentencer_T2 |
150-305 |
Sentence |
denotes |
Glucans are (1-3)-beta-D-linked polymers of glucose that are produced as fungal cell wall constituents and are also released into the extracellular milieu. |
| T2 |
150-305 |
Sentence |
denotes |
Glucans are (1-3)-beta-D-linked polymers of glucose that are produced as fungal cell wall constituents and are also released into the extracellular milieu. |
| T2 |
150-305 |
Sentence |
denotes |
Glucans are (1-3)-beta-D-linked polymers of glucose that are produced as fungal cell wall constituents and are also released into the extracellular milieu. |
| TextSentencer_T3 |
306-368 |
Sentence |
denotes |
Glucans modulate immune function via macrophage participation. |
| T3 |
306-368 |
Sentence |
denotes |
Glucans modulate immune function via macrophage participation. |
| T3 |
306-368 |
Sentence |
denotes |
Glucans modulate immune function via macrophage participation. |
| TextSentencer_T4 |
369-510 |
Sentence |
denotes |
The first step in macrophage activation by (1-3)-beta-D-glucans is thought to be the binding of the polymer to specific macrophage receptors. |
| T4 |
369-510 |
Sentence |
denotes |
The first step in macrophage activation by (1-3)-beta-D-glucans is thought to be the binding of the polymer to specific macrophage receptors. |
| T4 |
369-510 |
Sentence |
denotes |
The first step in macrophage activation by (1-3)-beta-D-glucans is thought to be the binding of the polymer to specific macrophage receptors. |
| TextSentencer_T5 |
511-782 |
Sentence |
denotes |
We examined the binding/uptake of a variety of water soluble (1-3)-beta-D-glucans and control polymers with different physicochemical properties to investigate the relationship between polymer structure and receptor binding in the CR3- human promonocytic cell line, U937. |
| T5 |
511-782 |
Sentence |
denotes |
We examined the binding/uptake of a variety of water soluble (1-3)-beta-D-glucans and control polymers with different physicochemical properties to investigate the relationship between polymer structure and receptor binding in the CR3- human promonocytic cell line, U937. |
| T5 |
511-782 |
Sentence |
denotes |
We examined the binding/uptake of a variety of water soluble (1-3)-beta-D-glucans and control polymers with different physicochemical properties to investigate the relationship between polymer structure and receptor binding in the CR3- human promonocytic cell line, U937. |
| TextSentencer_T6 |
783-921 |
Sentence |
denotes |
We observed that the U937 receptors were specific for (1-->3)-beta-D-glucan binding, since mannan, dextran, or barley glucan did not bind. |
| T6 |
783-921 |
Sentence |
denotes |
We observed that the U937 receptors were specific for (1-->3)-beta-D-glucan binding, since mannan, dextran, or barley glucan did not bind. |
| T6 |
783-921 |
Sentence |
denotes |
We observed that the U937 receptors were specific for (1-->3)-beta-D-glucan binding, since mannan, dextran, or barley glucan did not bind. |
| TextSentencer_T7 |
922-1087 |
Sentence |
denotes |
Scleroglucan exhibited the highest binding affinity with an IC(50)of 23 nM, three orders of magnitude greater than the other (1-->3)-beta-D-glucan polymers examined. |
| T7 |
922-1087 |
Sentence |
denotes |
Scleroglucan exhibited the highest binding affinity with an IC(50)of 23 nM, three orders of magnitude greater than the other (1-->3)-beta-D-glucan polymers examined. |
| T7 |
922-1087 |
Sentence |
denotes |
Scleroglucan exhibited the highest binding affinity with an IC(50)of 23 nM, three orders of magnitude greater than the other (1-->3)-beta-D-glucan polymers examined. |
| TextSentencer_T8 |
1088-1238 |
Sentence |
denotes |
The rank order competitive binding affinities for the glucan polymers were scleroglucan>schizophyllan > laminarin > glucan phosphate > glucan sulfate. |
| T8 |
1088-1238 |
Sentence |
denotes |
The rank order competitive binding affinities for the glucan polymers were scleroglucan>schizophyllan > laminarin > glucan phosphate > glucan sulfate. |
| T8 |
1088-1238 |
Sentence |
denotes |
The rank order competitive binding affinities for the glucan polymers were scleroglucan>schizophyllan > laminarin > glucan phosphate > glucan sulfate. |
| TextSentencer_T9 |
1239-1327 |
Sentence |
denotes |
Scleroglucan also exhibited a triple helical solution structure (nu = 1.82, beta = 0.8). |
| T9 |
1239-1327 |
Sentence |
denotes |
Scleroglucan also exhibited a triple helical solution structure (nu = 1.82, beta = 0.8). |
| T9 |
1239-1327 |
Sentence |
denotes |
Scleroglucan also exhibited a triple helical solution structure (nu = 1.82, beta = 0.8). |
| TextSentencer_T10 |
1328-1388 |
Sentence |
denotes |
There were two different binding/uptake sites on U937 cells. |
| T10 |
1328-1388 |
Sentence |
denotes |
There were two different binding/uptake sites on U937 cells. |
| T10 |
1328-1388 |
Sentence |
denotes |
There were two different binding/uptake sites on U937 cells. |
| TextSentencer_T11 |
1389-1469 |
Sentence |
denotes |
Glucan phosphate and schizophyllan interacted nonselectively with the two sites. |
| T11 |
1389-1469 |
Sentence |
denotes |
Glucan phosphate and schizophyllan interacted nonselectively with the two sites. |
| T11 |
1389-1469 |
Sentence |
denotes |
Glucan phosphate and schizophyllan interacted nonselectively with the two sites. |
| TextSentencer_T12 |
1470-1605 |
Sentence |
denotes |
Scleroglucan and glucan sulfate interacted preferentially with one site, while laminarin interacted preferentially with the other site. |
| T12 |
1470-1605 |
Sentence |
denotes |
Scleroglucan and glucan sulfate interacted preferentially with one site, while laminarin interacted preferentially with the other site. |
| T12 |
1470-1605 |
Sentence |
denotes |
Scleroglucan and glucan sulfate interacted preferentially with one site, while laminarin interacted preferentially with the other site. |
| TextSentencer_T13 |
1606-1898 |
Sentence |
denotes |
These data indicate that U937 cells have at least two non-CR3 receptor(s) which specifically interact with (1-->3)-beta-D-glucans and that the triple helical solution conformation, molecular weight and charge of the glucan polymer may be important determinants in receptor ligand interaction. |
| T13 |
1606-1898 |
Sentence |
denotes |
These data indicate that U937 cells have at least two non-CR3 receptor(s) which specifically interact with (1-->3)-beta-D-glucans and that the triple helical solution conformation, molecular weight and charge of the glucan polymer may be important determinants in receptor ligand interaction. |
| T13 |
1606-1898 |
Sentence |
denotes |
These data indicate that U937 cells have at least two non-CR3 receptor(s) which specifically interact with (1-->3)-beta-D-glucans and that the triple helical solution conformation, molecular weight and charge of the glucan polymer may be important determinants in receptor ligand interaction. |