| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-131 |
Sentence |
denotes |
Interaction between galectin-3 and FcgammaRII induces down-regulation of IL-5 gene: implication of the promoter sequence IL-5REIII. |
| T1 |
0-131 |
Sentence |
denotes |
Interaction between galectin-3 and FcgammaRII induces down-regulation of IL-5 gene: implication of the promoter sequence IL-5REIII. |
| T1 |
0-131 |
Sentence |
denotes |
Interaction between galectin-3 and FcgammaRII induces down-regulation of IL-5 gene: implication of the promoter sequence IL-5REIII. |
| TextSentencer_T2 |
132-391 |
Sentence |
denotes |
Our previous work demonstrated the capacity of galectin-3 (a beta-galactoside binding animal lectin) to inhibit IL-5 gene expression in different cell types, but the interaction of lectin with the cells and the pathways for the inhibition process are unknown. |
| T2 |
132-391 |
Sentence |
denotes |
Our previous work demonstrated the capacity of galectin-3 (a beta-galactoside binding animal lectin) to inhibit IL-5 gene expression in different cell types, but the interaction of lectin with the cells and the pathways for the inhibition process are unknown. |
| T2 |
132-391 |
Sentence |
denotes |
Our previous work demonstrated the capacity of galectin-3 (a beta-galactoside binding animal lectin) to inhibit IL-5 gene expression in different cell types, but the interaction of lectin with the cells and the pathways for the inhibition process are unknown. |
| TextSentencer_T3 |
392-473 |
Sentence |
denotes |
One of the purposes of this work was to study the cellular ligand for galectin-3. |
| T3 |
392-473 |
Sentence |
denotes |
One of the purposes of this work was to study the cellular ligand for galectin-3. |
| T3 |
392-473 |
Sentence |
denotes |
One of the purposes of this work was to study the cellular ligand for galectin-3. |
| TextSentencer_T4 |
474-719 |
Sentence |
denotes |
We have demonstrated that galectin-3 can bind to the low affinity IgG receptor (FcgammaRII or CD32) by using different experimental approaches, such as flow cytometry, fusion protein GST technology, and with a model of FcgammaRII-deficient mice. |
| T4 |
474-719 |
Sentence |
denotes |
We have demonstrated that galectin-3 can bind to the low affinity IgG receptor (FcgammaRII or CD32) by using different experimental approaches, such as flow cytometry, fusion protein GST technology, and with a model of FcgammaRII-deficient mice. |
| T4 |
474-719 |
Sentence |
denotes |
We have demonstrated that galectin-3 can bind to the low affinity IgG receptor (FcgammaRII or CD32) by using different experimental approaches, such as flow cytometry, fusion protein GST technology, and with a model of FcgammaRII-deficient mice. |
| TextSentencer_T5 |
720-873 |
Sentence |
denotes |
To further analyze the interaction between FcgammaRII and galectin-3, and its implication in IL-5 gene down-regulation we used FcgammaRII-deficient mice. |
| T5 |
720-873 |
Sentence |
denotes |
To further analyze the interaction between FcgammaRII and galectin-3, and its implication in IL-5 gene down-regulation we used FcgammaRII-deficient mice. |
| T5 |
720-873 |
Sentence |
denotes |
To further analyze the interaction between FcgammaRII and galectin-3, and its implication in IL-5 gene down-regulation we used FcgammaRII-deficient mice. |
| TextSentencer_T6 |
874-978 |
Sentence |
denotes |
When PBMC from these mice were incubated with galectin-3, the expression of the IL-5 gene was unchanged. |
| T6 |
874-978 |
Sentence |
denotes |
When PBMC from these mice were incubated with galectin-3, the expression of the IL-5 gene was unchanged. |
| T6 |
874-978 |
Sentence |
denotes |
When PBMC from these mice were incubated with galectin-3, the expression of the IL-5 gene was unchanged. |
| TextSentencer_T7 |
979-1121 |
Sentence |
denotes |
However, when PBMC from wild type mice and FcgammaRIII-deficient mice were incubated with galectin-3, IL-5 gene expression was down-regulated. |
| T7 |
979-1121 |
Sentence |
denotes |
However, when PBMC from wild type mice and FcgammaRIII-deficient mice were incubated with galectin-3, IL-5 gene expression was down-regulated. |
| T7 |
979-1121 |
Sentence |
denotes |
However, when PBMC from wild type mice and FcgammaRIII-deficient mice were incubated with galectin-3, IL-5 gene expression was down-regulated. |
| TextSentencer_T8 |
1122-1220 |
Sentence |
denotes |
Finally, we studied the implication of the negative regulatory sequence in the IL-5 gene promoter. |
| T8 |
1122-1220 |
Sentence |
denotes |
Finally, we studied the implication of the negative regulatory sequence in the IL-5 gene promoter. |
| T8 |
1122-1220 |
Sentence |
denotes |
Finally, we studied the implication of the negative regulatory sequence in the IL-5 gene promoter. |
| TextSentencer_T9 |
1221-1311 |
Sentence |
denotes |
In the presence of galectin-3, a DNA-protein complex was formed with the IL-5REIII region. |
| T9 |
1221-1311 |
Sentence |
denotes |
In the presence of galectin-3, a DNA-protein complex was formed with the IL-5REIII region. |
| T9 |
1221-1311 |
Sentence |
denotes |
In the presence of galectin-3, a DNA-protein complex was formed with the IL-5REIII region. |
| TextSentencer_T10 |
1312-1382 |
Sentence |
denotes |
This complex was not observed when unrelated oligonucleotide was used. |
| T10 |
1312-1382 |
Sentence |
denotes |
This complex was not observed when unrelated oligonucleotide was used. |
| T10 |
1312-1382 |
Sentence |
denotes |
This complex was not observed when unrelated oligonucleotide was used. |
| TextSentencer_T11 |
1383-1480 |
Sentence |
denotes |
So, galectin-3 induces a pathway, which activates a transcription factor that binds to IL-5REIII. |
| T11 |
1383-1480 |
Sentence |
denotes |
So, galectin-3 induces a pathway, which activates a transcription factor that binds to IL-5REIII. |
| T11 |
1383-1480 |
Sentence |
denotes |
So, galectin-3 induces a pathway, which activates a transcription factor that binds to IL-5REIII. |
| TextSentencer_T12 |
1481-1547 |
Sentence |
denotes |
This interaction is capable of inhibiting IL-5 gene transcription. |
| T12 |
1481-1547 |
Sentence |
denotes |
This interaction is capable of inhibiting IL-5 gene transcription. |
| T12 |
1481-1547 |
Sentence |
denotes |
This interaction is capable of inhibiting IL-5 gene transcription. |