Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-73 |
Sentence |
denotes |
A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome). |
T1 |
0-73 |
Sentence |
denotes |
A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome). |
T1 |
0-73 |
Sentence |
denotes |
A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome). |
TextSentencer_T2 |
74-338 |
Sentence |
denotes |
Mucopolysaccharidosis type III A (MPS III A, Sanfilippo syndrome) is a rare, autosomal recessive, lysosomal storage disease characterized by accumulation of heparan sulfate secondary to defective function of the lysosomal enzyme heparan N- sulfatase (sulfamidase). |
T2 |
74-338 |
Sentence |
denotes |
Mucopolysaccharidosis type III A (MPS III A, Sanfilippo syndrome) is a rare, autosomal recessive, lysosomal storage disease characterized by accumulation of heparan sulfate secondary to defective function of the lysosomal enzyme heparan N- sulfatase (sulfamidase). |
T2 |
74-338 |
Sentence |
denotes |
Mucopolysaccharidosis type III A (MPS III A, Sanfilippo syndrome) is a rare, autosomal recessive, lysosomal storage disease characterized by accumulation of heparan sulfate secondary to defective function of the lysosomal enzyme heparan N- sulfatase (sulfamidase). |
TextSentencer_T3 |
339-451 |
Sentence |
denotes |
Here we describe a spontaneous mouse mutant that replicates many of the features found in MPS III A in children. |
T3 |
339-451 |
Sentence |
denotes |
Here we describe a spontaneous mouse mutant that replicates many of the features found in MPS III A in children. |
T3 |
339-451 |
Sentence |
denotes |
Here we describe a spontaneous mouse mutant that replicates many of the features found in MPS III A in children. |
TextSentencer_T4 |
452-607 |
Sentence |
denotes |
Brain sections revealed neurons with distended lysosomes filled with membranous and floccular materials with some having a classical zebra body morphology. |
T4 |
452-607 |
Sentence |
denotes |
Brain sections revealed neurons with distended lysosomes filled with membranous and floccular materials with some having a classical zebra body morphology. |
T4 |
452-607 |
Sentence |
denotes |
Brain sections revealed neurons with distended lysosomes filled with membranous and floccular materials with some having a classical zebra body morphology. |
TextSentencer_T5 |
608-758 |
Sentence |
denotes |
Storage materials were also present in lysosomes of cells of many other tissues, and these often stained positively with periodic-acid Schiff reagent. |
T5 |
608-758 |
Sentence |
denotes |
Storage materials were also present in lysosomes of cells of many other tissues, and these often stained positively with periodic-acid Schiff reagent. |
T5 |
608-758 |
Sentence |
denotes |
Storage materials were also present in lysosomes of cells of many other tissues, and these often stained positively with periodic-acid Schiff reagent. |
TextSentencer_T6 |
759-862 |
Sentence |
denotes |
Affected mice usually died at 7-10 months of age exhibiting a distended bladder and hepatosplenomegaly. |
T6 |
759-862 |
Sentence |
denotes |
Affected mice usually died at 7-10 months of age exhibiting a distended bladder and hepatosplenomegaly. |
T6 |
759-862 |
Sentence |
denotes |
Affected mice usually died at 7-10 months of age exhibiting a distended bladder and hepatosplenomegaly. |
TextSentencer_T7 |
863-1016 |
Sentence |
denotes |
Heparan sulfate isolated from urine and brain had nonreducing end glucosamine- N -sulfate residues that were digested with recombinant human sulfamidase. |
T7 |
863-1016 |
Sentence |
denotes |
Heparan sulfate isolated from urine and brain had nonreducing end glucosamine- N -sulfate residues that were digested with recombinant human sulfamidase. |
T7 |
863-1016 |
Sentence |
denotes |
Heparan sulfate isolated from urine and brain had nonreducing end glucosamine- N -sulfate residues that were digested with recombinant human sulfamidase. |
TextSentencer_T8 |
1017-1113 |
Sentence |
denotes |
Enzyme assays of liver and brain extracts revealed a dramatic reduction in sulfamidase activity. |
T8 |
1017-1113 |
Sentence |
denotes |
Enzyme assays of liver and brain extracts revealed a dramatic reduction in sulfamidase activity. |
T8 |
1017-1113 |
Sentence |
denotes |
Enzyme assays of liver and brain extracts revealed a dramatic reduction in sulfamidase activity. |
TextSentencer_T9 |
1114-1278 |
Sentence |
denotes |
Other lysosomal hydrolases that degrade heparan sulfate or other glycans and glycosaminoglycans were either normal, or were somewhat increased in specific activity. |
T9 |
1114-1278 |
Sentence |
denotes |
Other lysosomal hydrolases that degrade heparan sulfate or other glycans and glycosaminoglycans were either normal, or were somewhat increased in specific activity. |
T9 |
1114-1278 |
Sentence |
denotes |
Other lysosomal hydrolases that degrade heparan sulfate or other glycans and glycosaminoglycans were either normal, or were somewhat increased in specific activity. |
TextSentencer_T10 |
1279-1467 |
Sentence |
denotes |
The MPS III A mouse provides an excellent model for evaluating pathogenic mechanisms of disease and for testing treatment strategies, including enzyme or cell replacement and gene therapy. |
T10 |
1279-1467 |
Sentence |
denotes |
The MPS III A mouse provides an excellent model for evaluating pathogenic mechanisms of disease and for testing treatment strategies, including enzyme or cell replacement and gene therapy. |
T10 |
1279-1467 |
Sentence |
denotes |
The MPS III A mouse provides an excellent model for evaluating pathogenic mechanisms of disease and for testing treatment strategies, including enzyme or cell replacement and gene therapy. |