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PubMed:10561464 JSONTXT 52 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-73 Sentence denotes A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome).
T1 0-73 Sentence denotes A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome).
T1 0-73 Sentence denotes A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome).
TextSentencer_T2 74-338 Sentence denotes Mucopolysaccharidosis type III A (MPS III A, Sanfilippo syndrome) is a rare, autosomal recessive, lysosomal storage disease characterized by accumulation of heparan sulfate secondary to defective function of the lysosomal enzyme heparan N- sulfatase (sulfamidase).
T2 74-338 Sentence denotes Mucopolysaccharidosis type III A (MPS III A, Sanfilippo syndrome) is a rare, autosomal recessive, lysosomal storage disease characterized by accumulation of heparan sulfate secondary to defective function of the lysosomal enzyme heparan N- sulfatase (sulfamidase).
T2 74-338 Sentence denotes Mucopolysaccharidosis type III A (MPS III A, Sanfilippo syndrome) is a rare, autosomal recessive, lysosomal storage disease characterized by accumulation of heparan sulfate secondary to defective function of the lysosomal enzyme heparan N- sulfatase (sulfamidase).
TextSentencer_T3 339-451 Sentence denotes Here we describe a spontaneous mouse mutant that replicates many of the features found in MPS III A in children.
T3 339-451 Sentence denotes Here we describe a spontaneous mouse mutant that replicates many of the features found in MPS III A in children.
T3 339-451 Sentence denotes Here we describe a spontaneous mouse mutant that replicates many of the features found in MPS III A in children.
TextSentencer_T4 452-607 Sentence denotes Brain sections revealed neurons with distended lysosomes filled with membranous and floccular materials with some having a classical zebra body morphology.
T4 452-607 Sentence denotes Brain sections revealed neurons with distended lysosomes filled with membranous and floccular materials with some having a classical zebra body morphology.
T4 452-607 Sentence denotes Brain sections revealed neurons with distended lysosomes filled with membranous and floccular materials with some having a classical zebra body morphology.
TextSentencer_T5 608-758 Sentence denotes Storage materials were also present in lysosomes of cells of many other tissues, and these often stained positively with periodic-acid Schiff reagent.
T5 608-758 Sentence denotes Storage materials were also present in lysosomes of cells of many other tissues, and these often stained positively with periodic-acid Schiff reagent.
T5 608-758 Sentence denotes Storage materials were also present in lysosomes of cells of many other tissues, and these often stained positively with periodic-acid Schiff reagent.
TextSentencer_T6 759-862 Sentence denotes Affected mice usually died at 7-10 months of age exhibiting a distended bladder and hepatosplenomegaly.
T6 759-862 Sentence denotes Affected mice usually died at 7-10 months of age exhibiting a distended bladder and hepatosplenomegaly.
T6 759-862 Sentence denotes Affected mice usually died at 7-10 months of age exhibiting a distended bladder and hepatosplenomegaly.
TextSentencer_T7 863-1016 Sentence denotes Heparan sulfate isolated from urine and brain had nonreducing end glucosamine- N -sulfate residues that were digested with recombinant human sulfamidase.
T7 863-1016 Sentence denotes Heparan sulfate isolated from urine and brain had nonreducing end glucosamine- N -sulfate residues that were digested with recombinant human sulfamidase.
T7 863-1016 Sentence denotes Heparan sulfate isolated from urine and brain had nonreducing end glucosamine- N -sulfate residues that were digested with recombinant human sulfamidase.
TextSentencer_T8 1017-1113 Sentence denotes Enzyme assays of liver and brain extracts revealed a dramatic reduction in sulfamidase activity.
T8 1017-1113 Sentence denotes Enzyme assays of liver and brain extracts revealed a dramatic reduction in sulfamidase activity.
T8 1017-1113 Sentence denotes Enzyme assays of liver and brain extracts revealed a dramatic reduction in sulfamidase activity.
TextSentencer_T9 1114-1278 Sentence denotes Other lysosomal hydrolases that degrade heparan sulfate or other glycans and glycosaminoglycans were either normal, or were somewhat increased in specific activity.
T9 1114-1278 Sentence denotes Other lysosomal hydrolases that degrade heparan sulfate or other glycans and glycosaminoglycans were either normal, or were somewhat increased in specific activity.
T9 1114-1278 Sentence denotes Other lysosomal hydrolases that degrade heparan sulfate or other glycans and glycosaminoglycans were either normal, or were somewhat increased in specific activity.
TextSentencer_T10 1279-1467 Sentence denotes The MPS III A mouse provides an excellent model for evaluating pathogenic mechanisms of disease and for testing treatment strategies, including enzyme or cell replacement and gene therapy.
T10 1279-1467 Sentence denotes The MPS III A mouse provides an excellent model for evaluating pathogenic mechanisms of disease and for testing treatment strategies, including enzyme or cell replacement and gene therapy.
T10 1279-1467 Sentence denotes The MPS III A mouse provides an excellent model for evaluating pathogenic mechanisms of disease and for testing treatment strategies, including enzyme or cell replacement and gene therapy.