| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-139 |
Sentence |
denotes |
The structural heterogeneity of the lipooligosaccharide (LOS) expressed by pathogenic non-typeable Haemophilus influenzae strain NTHi 9274. |
| T1 |
0-139 |
Sentence |
denotes |
The structural heterogeneity of the lipooligosaccharide (LOS) expressed by pathogenic non-typeable Haemophilus influenzae strain NTHi 9274. |
| T1 |
0-139 |
Sentence |
denotes |
The structural heterogeneity of the lipooligosaccharide (LOS) expressed by pathogenic non-typeable Haemophilus influenzae strain NTHi 9274. |
| TextSentencer_T2 |
140-303 |
Sentence |
denotes |
Nontypeable Haemophilus influenzae (NTHi) is an important pathogen responsible for otitis media in children and of pneumonitis in adults with depressed resistance. |
| T2 |
140-303 |
Sentence |
denotes |
Nontypeable Haemophilus influenzae (NTHi) is an important pathogen responsible for otitis media in children and of pneumonitis in adults with depressed resistance. |
| T2 |
140-303 |
Sentence |
denotes |
Nontypeable Haemophilus influenzae (NTHi) is an important pathogen responsible for otitis media in children and of pneumonitis in adults with depressed resistance. |
| TextSentencer_T3 |
304-436 |
Sentence |
denotes |
NTHi is acapsular and, therefore, capsular polysaccharide-based vaccines are ineffective for preventing infections by this pathogen. |
| T3 |
304-436 |
Sentence |
denotes |
NTHi is acapsular and, therefore, capsular polysaccharide-based vaccines are ineffective for preventing infections by this pathogen. |
| T3 |
304-436 |
Sentence |
denotes |
NTHi is acapsular and, therefore, capsular polysaccharide-based vaccines are ineffective for preventing infections by this pathogen. |
| TextSentencer_T4 |
437-708 |
Sentence |
denotes |
Recently it was found that a detoxified lipooligo-saccharide (LOS) conjugate from NTHi 9274 induced bactericidal antibodies effective against a large number of NTHi isolates, and conferred protection against NTHi otitis media in chinchillas (X.-X.Gu et al., 1996, Infect. |
| T4 |
437-708 |
Sentence |
denotes |
Recently it was found that a detoxified lipooligo-saccharide (LOS) conjugate from NTHi 9274 induced bactericidal antibodies effective against a large number of NTHi isolates, and conferred protection against NTHi otitis media in chinchillas (X.-X.Gu et al., 1996, Infect. |
| T4 |
437-785 |
Sentence |
denotes |
Recently it was found that a detoxified lipooligo-saccharide (LOS) conjugate from NTHi 9274 induced bactericidal antibodies effective against a large number of NTHi isolates, and conferred protection against NTHi otitis media in chinchillas (X.-X.Gu et al., 1996, Infect. Immun.,64, 4047-4053; X. -X.Gu et al., 1997., Infect. Immun.,65, 4488-4493). |
| TextSentencer_T5 |
709-762 |
Sentence |
denotes |
Immun.,64, 4047-4053; X. -X.Gu et al., 1997., Infect. |
| T5 |
709-762 |
Sentence |
denotes |
Immun.,64, 4047-4053; X. -X.Gu et al., 1997., Infect. |
| TextSentencer_T6 |
763-785 |
Sentence |
denotes |
Immun.,65, 4488-4493). |
| T6 |
763-785 |
Sentence |
denotes |
Immun.,65, 4488-4493). |
| TextSentencer_T7 |
786-871 |
Sentence |
denotes |
In this paper we report the chemical character-ization of the LOS from NTHi 9274 LOS. |
| T5 |
786-871 |
Sentence |
denotes |
In this paper we report the chemical character-ization of the LOS from NTHi 9274 LOS. |
| T7 |
786-871 |
Sentence |
denotes |
In this paper we report the chemical character-ization of the LOS from NTHi 9274 LOS. |
| TextSentencer_T8 |
872-987 |
Sentence |
denotes |
NTHi is capable of expressing a heterogenous population of LOS exhibited by multiple oligosaccharide (OS) epitopes. |
| T6 |
872-987 |
Sentence |
denotes |
NTHi is capable of expressing a heterogenous population of LOS exhibited by multiple oligosaccharide (OS) epitopes. |
| T8 |
872-987 |
Sentence |
denotes |
NTHi is capable of expressing a heterogenous population of LOS exhibited by multiple oligosaccharide (OS) epitopes. |
| TextSentencer_T9 |
988-1112 |
Sentence |
denotes |
OSs released from the LOS of NTHi 9274 by mild acid hydrolysis were purified using Bio-Gel P4 gel permeation chromatography. |
| T7 |
988-1112 |
Sentence |
denotes |
OSs released from the LOS of NTHi 9274 by mild acid hydrolysis were purified using Bio-Gel P4 gel permeation chromatography. |
| T9 |
988-1112 |
Sentence |
denotes |
OSs released from the LOS of NTHi 9274 by mild acid hydrolysis were purified using Bio-Gel P4 gel permeation chromatography. |
| TextSentencer_T10 |
1113-1398 |
Sentence |
denotes |
The OSs were characterized by glycosyl composition analysis, glycosyl linkage analysis, nuclear magnetic resonance spectroscopy (NMR), fast atom bombardment mass spectro-metry (FAB-MS), matrix-assisted laser desorption time of flight mass spectro-metry (MALDITOF-MS), and tandem MS/MS. |
| T8 |
1113-1398 |
Sentence |
denotes |
The OSs were characterized by glycosyl composition analysis, glycosyl linkage analysis, nuclear magnetic resonance spectroscopy (NMR), fast atom bombardment mass spectro-metry (FAB-MS), matrix-assisted laser desorption time of flight mass spectro-metry (MALDITOF-MS), and tandem MS/MS. |
| T10 |
1113-1398 |
Sentence |
denotes |
The OSs were characterized by glycosyl composition analysis, glycosyl linkage analysis, nuclear magnetic resonance spectroscopy (NMR), fast atom bombardment mass spectro-metry (FAB-MS), matrix-assisted laser desorption time of flight mass spectro-metry (MALDITOF-MS), and tandem MS/MS. |
| TextSentencer_T11 |
1399-1448 |
Sentence |
denotes |
At least 17 different OS molecules were observed. |
| T9 |
1399-1448 |
Sentence |
denotes |
At least 17 different OS molecules were observed. |
| T11 |
1399-1448 |
Sentence |
denotes |
At least 17 different OS molecules were observed. |
| TextSentencer_T12 |
1449-1552 |
Sentence |
denotes |
These contained variable glycosyl residues, phosphate (P), and phospho-ethanolamine (PEA) substituents. |
| T10 |
1449-1552 |
Sentence |
denotes |
These contained variable glycosyl residues, phosphate (P), and phospho-ethanolamine (PEA) substituents. |
| T12 |
1449-1552 |
Sentence |
denotes |
These contained variable glycosyl residues, phosphate (P), and phospho-ethanolamine (PEA) substituents. |
| TextSentencer_T13 |
1553-1657 |
Sentence |
denotes |
These molecules contained either three, four, or five hexoses, and all contained four heptosyl residues. |
| T11 |
1553-1657 |
Sentence |
denotes |
These molecules contained either three, four, or five hexoses, and all contained four heptosyl residues. |
| T13 |
1553-1657 |
Sentence |
denotes |
These molecules contained either three, four, or five hexoses, and all contained four heptosyl residues. |
| TextSentencer_T14 |
1658-1728 |
Sentence |
denotes |
The four heptosyl residues consisted of one D,D-Hep and three L,D-Hep. |
| T14 |
1658-1728 |
Sentence |
denotes |
The four heptosyl residues consisted of one D,D-Hep and three L,D-Hep. |
| T12 |
1658-1872 |
Sentence |
denotes |
The four heptosyl residues consisted of one D,D-Hep and three L,D-Hep. Dephosphorylation of the OSs with aqueous 48% hydrofluoric acid (HF) reduced the number of molecules to about to seven; Hex(1)-(7)Hep(4)Kdo(1). |
| TextSentencer_T15 |
1729-1872 |
Sentence |
denotes |
Dephosphorylation of the OSs with aqueous 48% hydrofluoric acid (HF) reduced the number of molecules to about to seven; Hex(1)-(7)Hep(4)Kdo(1). |
| T15 |
1729-1872 |
Sentence |
denotes |
Dephosphorylation of the OSs with aqueous 48% hydrofluoric acid (HF) reduced the number of molecules to about to seven; Hex(1)-(7)Hep(4)Kdo(1). |
| TextSentencer_T16 |
1873-1979 |
Sentence |
denotes |
Of these seven, Hex(2)Hep(4)Kdo(1), Hex(3)Hep(4)Kdo(1), and Hex(4)Hep(4)Kdo(1)were the major constituents. |
| T13 |
1873-1979 |
Sentence |
denotes |
Of these seven, Hex(2)Hep(4)Kdo(1), Hex(3)Hep(4)Kdo(1), and Hex(4)Hep(4)Kdo(1)were the major constituents. |
| T16 |
1873-1979 |
Sentence |
denotes |
Of these seven, Hex(2)Hep(4)Kdo(1), Hex(3)Hep(4)Kdo(1), and Hex(4)Hep(4)Kdo(1)were the major constituents. |
| TextSentencer_T17 |
1980-2128 |
Sentence |
denotes |
Thus, this NTHi LOS preparation is very heterogeneous, and contains structures different from those previously published for Haemophilus influenzae. |
| T14 |
1980-2128 |
Sentence |
denotes |
Thus, this NTHi LOS preparation is very heterogeneous, and contains structures different from those previously published for Haemophilus influenzae. |
| T17 |
1980-2128 |
Sentence |
denotes |
Thus, this NTHi LOS preparation is very heterogeneous, and contains structures different from those previously published for Haemophilus influenzae. |
| TextSentencer_T18 |
2129-2290 |
Sentence |
denotes |
The tandem MS/MS analysis and glycosyl linkage data suggest that the LOS oligosaccharides have the following structures where Hex is either a Glc or Gal residue. |
| T15 |
2129-2290 |
Sentence |
denotes |
The tandem MS/MS analysis and glycosyl linkage data suggest that the LOS oligosaccharides have the following structures where Hex is either a Glc or Gal residue. |
| T18 |
2129-2290 |
Sentence |
denotes |
The tandem MS/MS analysis and glycosyl linkage data suggest that the LOS oligosaccharides have the following structures where Hex is either a Glc or Gal residue. |