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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-181 Sentence denotes Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens.
T1 0-181 Sentence denotes Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens.
T1 0-181 Sentence denotes Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens.
TextSentencer_T2 182-324 Sentence denotes The sialyl-Tn (sTn) antigen is a well known cancer-associated antigen, the expression of which is related to the prognosis of cancer patients.
T2 182-324 Sentence denotes The sialyl-Tn (sTn) antigen is a well known cancer-associated antigen, the expression of which is related to the prognosis of cancer patients.
T2 182-324 Sentence denotes The sialyl-Tn (sTn) antigen is a well known cancer-associated antigen, the expression of which is related to the prognosis of cancer patients.
TextSentencer_T3 325-482 Sentence denotes We aimed to isolate a human gene encoding an N -acetylgalactosamine alpha2,6-sialyltransferase which synthesizes sTn antigen, and to characterize the enzyme.
T3 325-482 Sentence denotes We aimed to isolate a human gene encoding an N -acetylgalactosamine alpha2,6-sialyltransferase which synthesizes sTn antigen, and to characterize the enzyme.
T3 325-482 Sentence denotes We aimed to isolate a human gene encoding an N -acetylgalactosamine alpha2,6-sialyltransferase which synthesizes sTn antigen, and to characterize the enzyme.
TextSentencer_T4 483-798 Sentence denotes Degenerate primers encoding sialyl motifs were used for the polymerase chain reaction to amplify complementary DNAs prepared from RNAs of human pyloric mucosae with intestinal metaplasia, which abundantly expressed sTn antigen, followed by screening of full-length cDNAs using the amplified DNA fragment as a probe.
T4 483-798 Sentence denotes Degenerate primers encoding sialyl motifs were used for the polymerase chain reaction to amplify complementary DNAs prepared from RNAs of human pyloric mucosae with intestinal metaplasia, which abundantly expressed sTn antigen, followed by screening of full-length cDNAs using the amplified DNA fragment as a probe.
T4 483-798 Sentence denotes Degenerate primers encoding sialyl motifs were used for the polymerase chain reaction to amplify complementary DNAs prepared from RNAs of human pyloric mucosae with intestinal metaplasia, which abundantly expressed sTn antigen, followed by screening of full-length cDNAs using the amplified DNA fragment as a probe.
TextSentencer_T5 799-885 Sentence denotes We isolated two human cDNA clones, long-form (2.46 kb) and short-form (2.23 kb) cDNAs.
T5 799-885 Sentence denotes We isolated two human cDNA clones, long-form (2.46 kb) and short-form (2.23 kb) cDNAs.
T5 799-885 Sentence denotes We isolated two human cDNA clones, long-form (2.46 kb) and short-form (2.23 kb) cDNAs.
TextSentencer_T6 886-963 Sentence denotes The former encodes an active enzyme with a predicted 600 amino acid sequence.
T6 886-963 Sentence denotes The former encodes an active enzyme with a predicted 600 amino acid sequence.
T6 886-963 Sentence denotes The former encodes an active enzyme with a predicted 600 amino acid sequence.
TextSentencer_T7 964-1038 Sentence denotes The latter, a splice-variant of the long-form, encodes an inactive enzyme.
T7 964-1038 Sentence denotes The latter, a splice-variant of the long-form, encodes an inactive enzyme.
T7 964-1038 Sentence denotes The latter, a splice-variant of the long-form, encodes an inactive enzyme.
TextSentencer_T8 1039-1149 Sentence denotes HCT15 human colorectal cancer cells stably expressing the long-form cDNA expressed sTn epitopes on O -glycans.
T8 1039-1149 Sentence denotes HCT15 human colorectal cancer cells stably expressing the long-form cDNA expressed sTn epitopes on O -glycans.
T8 1039-1149 Sentence denotes HCT15 human colorectal cancer cells stably expressing the long-form cDNA expressed sTn epitopes on O -glycans.
TextSentencer_T9 1150-1574 Sentence denotes The long form cDNA was considered to encode a human homologue of chick ST6GalNAc I for the following reasons: (1) the putative amino acid sequence showed greater homology to that of chick ST6GalNAc I (55%) compared to other sialyltransferases, (2) it encodes the extraordinarily long stem region that is a typical feature of chick ST6GalNAc I, and (3) the substrate specificity was very similar to that of chick ST6GalNAc I.
T9 1150-1574 Sentence denotes The long form cDNA was considered to encode a human homologue of chick ST6GalNAc I for the following reasons: (1) the putative amino acid sequence showed greater homology to that of chick ST6GalNAc I (55%) compared to other sialyltransferases, (2) it encodes the extraordinarily long stem region that is a typical feature of chick ST6GalNAc I, and (3) the substrate specificity was very similar to that of chick ST6GalNAc I.
T9 1150-1762 Sentence denotes The long form cDNA was considered to encode a human homologue of chick ST6GalNAc I for the following reasons: (1) the putative amino acid sequence showed greater homology to that of chick ST6GalNAc I (55%) compared to other sialyltransferases, (2) it encodes the extraordinarily long stem region that is a typical feature of chick ST6GalNAc I, and (3) the substrate specificity was very similar to that of chick ST6GalNAc I. In situ hybridization demonstrated that the localization of transcripts correlated well with that of sTn antigen in gastric cancer cells and Goblet cells in intestinal metaplastic glands.
TextSentencer_T10 1575-1762 Sentence denotes In situ hybridization demonstrated that the localization of transcripts correlated well with that of sTn antigen in gastric cancer cells and Goblet cells in intestinal metaplastic glands.
T10 1575-1762 Sentence denotes In situ hybridization demonstrated that the localization of transcripts correlated well with that of sTn antigen in gastric cancer cells and Goblet cells in intestinal metaplastic glands.
TextSentencer_T11 1763-1898 Sentence denotes Thus, we determined that the long-form cDNA of the human ST6GalNAc I gene encodes the probable candidate for the human sTn synthase(s).
T10 1763-1898 Sentence denotes Thus, we determined that the long-form cDNA of the human ST6GalNAc I gene encodes the probable candidate for the human sTn synthase(s).
T11 1763-1898 Sentence denotes Thus, we determined that the long-form cDNA of the human ST6GalNAc I gene encodes the probable candidate for the human sTn synthase(s).