| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-121 |
Sentence |
denotes |
Sequential biosynthesis of sulfated and/or sialylated Lewis x determinants by transferases of the human bronchial mucosa. |
| T1 |
0-121 |
Sentence |
denotes |
Sequential biosynthesis of sulfated and/or sialylated Lewis x determinants by transferases of the human bronchial mucosa. |
| T1 |
0-121 |
Sentence |
denotes |
Sequential biosynthesis of sulfated and/or sialylated Lewis x determinants by transferases of the human bronchial mucosa. |
| TextSentencer_T2 |
122-383 |
Sentence |
denotes |
The structural determination of sulfated carbohydrate chains from a cystic fibrosis patient respiratory mucins has shown that sulfation may occur either on the C-3 of the terminal Gal, or on the C-6 of the GlcNAc residue of a terminal N -acetyllactosamine unit. |
| T2 |
122-383 |
Sentence |
denotes |
The structural determination of sulfated carbohydrate chains from a cystic fibrosis patient respiratory mucins has shown that sulfation may occur either on the C-3 of the terminal Gal, or on the C-6 of the GlcNAc residue of a terminal N -acetyllactosamine unit. |
| T2 |
122-383 |
Sentence |
denotes |
The structural determination of sulfated carbohydrate chains from a cystic fibrosis patient respiratory mucins has shown that sulfation may occur either on the C-3 of the terminal Gal, or on the C-6 of the GlcNAc residue of a terminal N -acetyllactosamine unit. |
| TextSentencer_T3 |
384-553 |
Sentence |
denotes |
The two enzymes responsible for the transfer of sulfate from PAPS to the C-3 of Gal or to the C-6 of GlcNAc residues have been characterized in human respiratory mucosa. |
| T3 |
384-553 |
Sentence |
denotes |
The two enzymes responsible for the transfer of sulfate from PAPS to the C-3 of Gal or to the C-6 of GlcNAc residues have been characterized in human respiratory mucosa. |
| T3 |
384-553 |
Sentence |
denotes |
The two enzymes responsible for the transfer of sulfate from PAPS to the C-3 of Gal or to the C-6 of GlcNAc residues have been characterized in human respiratory mucosa. |
| TextSentencer_T4 |
554-804 |
Sentence |
denotes |
These two enzymes, in conjunction with fucosyl- and sialyltransferases, allow the synthesis of different sulfated epitopes such as 3-sulfo Lewis x (with a 3- O -sulfated Gal), 6-sulfo Lewis x and 6-sulfo-sialyl Lewis x (with a 6- O -sulfated GlcNAc). |
| T4 |
554-804 |
Sentence |
denotes |
These two enzymes, in conjunction with fucosyl- and sialyltransferases, allow the synthesis of different sulfated epitopes such as 3-sulfo Lewis x (with a 3- O -sulfated Gal), 6-sulfo Lewis x and 6-sulfo-sialyl Lewis x (with a 6- O -sulfated GlcNAc). |
| T4 |
554-804 |
Sentence |
denotes |
These two enzymes, in conjunction with fucosyl- and sialyltransferases, allow the synthesis of different sulfated epitopes such as 3-sulfo Lewis x (with a 3- O -sulfated Gal), 6-sulfo Lewis x and 6-sulfo-sialyl Lewis x (with a 6- O -sulfated GlcNAc). |
| TextSentencer_T5 |
805-1084 |
Sentence |
denotes |
In the present study, the sequential biosynthesis of these epitopes has been investigated using microsomal fractions from human respiratory mucosa incubated with radiolabeled nucleotide-sugars or PAPS, and oligosaccharide acceptors, mostly prepared from human respiratory mucins. |
| T5 |
805-1084 |
Sentence |
denotes |
In the present study, the sequential biosynthesis of these epitopes has been investigated using microsomal fractions from human respiratory mucosa incubated with radiolabeled nucleotide-sugars or PAPS, and oligosaccharide acceptors, mostly prepared from human respiratory mucins. |
| T5 |
805-1084 |
Sentence |
denotes |
In the present study, the sequential biosynthesis of these epitopes has been investigated using microsomal fractions from human respiratory mucosa incubated with radiolabeled nucleotide-sugars or PAPS, and oligosaccharide acceptors, mostly prepared from human respiratory mucins. |
| TextSentencer_T6 |
1085-1216 |
Sentence |
denotes |
The structures of the radiolabeled products have been determined by their coelution in HPAEC with known oligosaccharidic standards. |
| T6 |
1085-1216 |
Sentence |
denotes |
The structures of the radiolabeled products have been determined by their coelution in HPAEC with known oligosaccharidic standards. |
| T6 |
1085-1216 |
Sentence |
denotes |
The structures of the radiolabeled products have been determined by their coelution in HPAEC with known oligosaccharidic standards. |
| TextSentencer_T7 |
1217-1555 |
Sentence |
denotes |
In the biosynthesis of 6- O -sulfated carbohydrate chains by the human respiratory mucosa, the 6- O -sulfation of a terminal nonreducing GlcNAc residue precedes beta1-4-galactosylation, alpha2-3-sialylation (to generate 6-sulfo-sialyl- N -acetyllactosamine), and alpha1-3-fucosylation (to generate the 6-sulfo-sialyl Lewis x determinant). |
| T7 |
1217-1555 |
Sentence |
denotes |
In the biosynthesis of 6- O -sulfated carbohydrate chains by the human respiratory mucosa, the 6- O -sulfation of a terminal nonreducing GlcNAc residue precedes beta1-4-galactosylation, alpha2-3-sialylation (to generate 6-sulfo-sialyl- N -acetyllactosamine), and alpha1-3-fucosylation (to generate the 6-sulfo-sialyl Lewis x determinant). |
| T7 |
1217-1555 |
Sentence |
denotes |
In the biosynthesis of 6- O -sulfated carbohydrate chains by the human respiratory mucosa, the 6- O -sulfation of a terminal nonreducing GlcNAc residue precedes beta1-4-galactosylation, alpha2-3-sialylation (to generate 6-sulfo-sialyl- N -acetyllactosamine), and alpha1-3-fucosylation (to generate the 6-sulfo-sialyl Lewis x determinant). |
| TextSentencer_T8 |
1556-1666 |
Sentence |
denotes |
The 3- O -sulfation of a terminal N -acetyllactosamine may occur if this carbohydrate unit is not substituted. |
| T8 |
1556-1666 |
Sentence |
denotes |
The 3- O -sulfation of a terminal N -acetyllactosamine may occur if this carbohydrate unit is not substituted. |
| T8 |
1556-1666 |
Sentence |
denotes |
The 3- O -sulfation of a terminal N -acetyllactosamine may occur if this carbohydrate unit is not substituted. |
| TextSentencer_T9 |
1667-1825 |
Sentence |
denotes |
Once an N -acetyllactosamine unit is synthesized, alpha1-3-fucosylation of the GlcNAc residue to generate a Lewis x structure blocks any further substitution. |
| T9 |
1667-1825 |
Sentence |
denotes |
Once an N -acetyllactosamine unit is synthesized, alpha1-3-fucosylation of the GlcNAc residue to generate a Lewis x structure blocks any further substitution. |
| T9 |
1667-1825 |
Sentence |
denotes |
Once an N -acetyllactosamine unit is synthesized, alpha1-3-fucosylation of the GlcNAc residue to generate a Lewis x structure blocks any further substitution. |
| TextSentencer_T10 |
1826-2010 |
Sentence |
denotes |
Therefore, the present study defines the pathways for the biosynthesis of Lewis x, sialyl Lewis x, sulfo Lewis x, and 6-sulfo-sialyl Lewis x determinants in the human bronchial mucosa. |
| T10 |
1826-2010 |
Sentence |
denotes |
Therefore, the present study defines the pathways for the biosynthesis of Lewis x, sialyl Lewis x, sulfo Lewis x, and 6-sulfo-sialyl Lewis x determinants in the human bronchial mucosa. |
| T10 |
1826-2010 |
Sentence |
denotes |
Therefore, the present study defines the pathways for the biosynthesis of Lewis x, sialyl Lewis x, sulfo Lewis x, and 6-sulfo-sialyl Lewis x determinants in the human bronchial mucosa. |