| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-113 |
Sentence |
denotes |
Further characterization of the combining sites of Bandeiraea (Griffonia) simplicifolia lectin-I, isolectin A(4). |
| T1 |
0-113 |
Sentence |
denotes |
Further characterization of the combining sites of Bandeiraea (Griffonia) simplicifolia lectin-I, isolectin A(4). |
| T1 |
0-113 |
Sentence |
denotes |
Further characterization of the combining sites of Bandeiraea (Griffonia) simplicifolia lectin-I, isolectin A(4). |
| TextSentencer_T2 |
114-305 |
Sentence |
denotes |
Bandeiraea (Griffonia) simplicifolia lectin-I, isolectin A(4)(GS I-A(4)), which is cytotoxic to the human colon cancer cell lines, is one of two lectin families derived from its seed extract. |
| T2 |
114-305 |
Sentence |
denotes |
Bandeiraea (Griffonia) simplicifolia lectin-I, isolectin A(4)(GS I-A(4)), which is cytotoxic to the human colon cancer cell lines, is one of two lectin families derived from its seed extract. |
| T2 |
114-305 |
Sentence |
denotes |
Bandeiraea (Griffonia) simplicifolia lectin-I, isolectin A(4)(GS I-A(4)), which is cytotoxic to the human colon cancer cell lines, is one of two lectin families derived from its seed extract. |
| TextSentencer_T3 |
306-394 |
Sentence |
denotes |
It contains only a homo-oligomer of subunit A, and is most specific for GalNAcalpha1-->. |
| T3 |
306-394 |
Sentence |
denotes |
It contains only a homo-oligomer of subunit A, and is most specific for GalNAcalpha1-->. |
| T3 |
306-394 |
Sentence |
denotes |
It contains only a homo-oligomer of subunit A, and is most specific for GalNAcalpha1-->. |
| TextSentencer_T4 |
395-639 |
Sentence |
denotes |
In order to elucidate the GS I-A(4)-glycoconjugate interactions in greater detail, the combining site of this lectin was further characterized by enzyme linked lectino-sorbent assay (ELLSA) and by inhibition of lectin-glycoprotein interactions. |
| T4 |
395-639 |
Sentence |
denotes |
In order to elucidate the GS I-A(4)-glycoconjugate interactions in greater detail, the combining site of this lectin was further characterized by enzyme linked lectino-sorbent assay (ELLSA) and by inhibition of lectin-glycoprotein interactions. |
| T4 |
395-639 |
Sentence |
denotes |
In order to elucidate the GS I-A(4)-glycoconjugate interactions in greater detail, the combining site of this lectin was further characterized by enzyme linked lectino-sorbent assay (ELLSA) and by inhibition of lectin-glycoprotein interactions. |
| TextSentencer_T5 |
640-1053 |
Sentence |
denotes |
This study has demonstrated that the Tn-containing glycoproteins tested, consisting of mammalian salivary glycoproteins (armadillo, asialo-hamster sublingual, asialo-ovine, -bovine, and -porcine submandibular), are bound strongly by GS I-A(4.)Among monovalent inhibitors so far tested, p-NO2-phenylalphaGalNAc is the most potent, suggesting that hydrophobic forces are important in the interaction of this lectin. |
| T5 |
640-1053 |
Sentence |
denotes |
This study has demonstrated that the Tn-containing glycoproteins tested, consisting of mammalian salivary glycoproteins (armadillo, asialo-hamster sublingual, asialo-ovine, -bovine, and -porcine submandibular), are bound strongly by GS I-A(4.)Among monovalent inhibitors so far tested, p-NO2-phenylalphaGalNAc is the most potent, suggesting that hydrophobic forces are important in the interaction of this lectin. |
| T5 |
640-1053 |
Sentence |
denotes |
This study has demonstrated that the Tn-containing glycoproteins tested, consisting of mammalian salivary glycoproteins (armadillo, asialo-hamster sublingual, asialo-ovine, -bovine, and -porcine submandibular), are bound strongly by GS I-A(4.)Among monovalent inhibitors so far tested, p-NO2-phenylalphaGalNAc is the most potent, suggesting that hydrophobic forces are important in the interaction of this lectin. |
| TextSentencer_T6 |
1054-1155 |
Sentence |
denotes |
GS I-A(4)is able to accommodate the monosaccharide GalNAc at the nonreducing end of oligosaccharides. |
| T6 |
1054-1155 |
Sentence |
denotes |
GS I-A(4)is able to accommodate the monosaccharide GalNAc at the nonreducing end of oligosaccharides. |
| T6 |
1054-1155 |
Sentence |
denotes |
GS I-A(4)is able to accommodate the monosaccharide GalNAc at the nonreducing end of oligosaccharides. |
| TextSentencer_T7 |
1156-1228 |
Sentence |
denotes |
This suggests that the combining site of the lectin is a shallow cavity. |
| T7 |
1156-1228 |
Sentence |
denotes |
This suggests that the combining site of the lectin is a shallow cavity. |
| T7 |
1156-1228 |
Sentence |
denotes |
This suggests that the combining site of the lectin is a shallow cavity. |
| TextSentencer_T8 |
1229-1353 |
Sentence |
denotes |
Among oligosaccharides and monosaccharides tested as inhibitors of the binding of GS I-A(4), the hierarchy of potencies are: |
| T8 |
1229-1353 |
Sentence |
denotes |
Among oligosaccharides and monosaccharides tested as inhibitors of the binding of GS I-A(4), the hierarchy of potencies are: |
| T8 |
1229-1353 |
Sentence |
denotes |
Among oligosaccharides and monosaccharides tested as inhibitors of the binding of GS I-A(4), the hierarchy of potencies are: |
| TextSentencer_T9 |
1354-1570 |
Sentence |
denotes |
GalNAcalpha1-->3GalNAcbeta1-->3Galalpha1-->4Galbeta 1-->4Glc (Forssman pentasaccharide) > GalNAcalpha1-->3(LFucalpha1-->2)Gal (blood group A)()> GalNAc > Galalpha1-->4Gal > Galalpha1-->3Gal (blood group B-like)> Gal. |
| T9 |
1354-1570 |
Sentence |
denotes |
GalNAcalpha1-->3GalNAcbeta1-->3Galalpha1-->4Galbeta 1-->4Glc (Forssman pentasaccharide) > GalNAcalpha1-->3(LFucalpha1-->2)Gal (blood group A)()> GalNAc > Galalpha1-->4Gal > Galalpha1-->3Gal (blood group B-like)> Gal. |
| T9 |
1354-1570 |
Sentence |
denotes |
GalNAcalpha1-->3GalNAcbeta1-->3Galalpha1-->4Galbeta 1-->4Glc (Forssman pentasaccharide) > GalNAcalpha1-->3(LFucalpha1-->2)Gal (blood group A)()> GalNAc > Galalpha1-->4Gal > Galalpha1-->3Gal (blood group B-like)> Gal. |