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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-164 Sentence denotes Enhancing therapeutic glycoprotein production in Chinese hamster ovary cells by metabolic engineering endogenous gene control with antisense DNA and gene targeting.
T1 0-164 Sentence denotes Enhancing therapeutic glycoprotein production in Chinese hamster ovary cells by metabolic engineering endogenous gene control with antisense DNA and gene targeting.
T1 0-164 Sentence denotes Enhancing therapeutic glycoprotein production in Chinese hamster ovary cells by metabolic engineering endogenous gene control with antisense DNA and gene targeting.
TextSentencer_T2 165-307 Sentence denotes Recombinant glycoprotein therapeutics have proven to be invaluable pharmaceuticals for the treatment of chronic and life-threatening diseases.
T2 165-307 Sentence denotes Recombinant glycoprotein therapeutics have proven to be invaluable pharmaceuticals for the treatment of chronic and life-threatening diseases.
T2 165-307 Sentence denotes Recombinant glycoprotein therapeutics have proven to be invaluable pharmaceuticals for the treatment of chronic and life-threatening diseases.
TextSentencer_T3 308-475 Sentence denotes Although these molecules are extraordinarily efficacious, many diseases have high dosage requirements of several hundred milligrams of protein for each administration.
T3 308-475 Sentence denotes Although these molecules are extraordinarily efficacious, many diseases have high dosage requirements of several hundred milligrams of protein for each administration.
T3 308-475 Sentence denotes Although these molecules are extraordinarily efficacious, many diseases have high dosage requirements of several hundred milligrams of protein for each administration.
TextSentencer_T4 476-538 Sentence denotes Multiple doses at this level are often required for treatment.
T4 476-538 Sentence denotes Multiple doses at this level are often required for treatment.
T4 476-538 Sentence denotes Multiple doses at this level are often required for treatment.
TextSentencer_T5 539-744 Sentence denotes One of the major challenges currently facing the biotechnology industry is the development of large-scale, cost-effective production and manufacturing processes of these biologically synthesized molecules.
T5 539-744 Sentence denotes One of the major challenges currently facing the biotechnology industry is the development of large-scale, cost-effective production and manufacturing processes of these biologically synthesized molecules.
T5 539-744 Sentence denotes One of the major challenges currently facing the biotechnology industry is the development of large-scale, cost-effective production and manufacturing processes of these biologically synthesized molecules.
TextSentencer_T6 745-928 Sentence denotes Metabolic engineering of animal cell expression hosts promises to address this challenge by substantially enhancing recombinant protein quality, productivity, and biological activity.
T6 745-928 Sentence denotes Metabolic engineering of animal cell expression hosts promises to address this challenge by substantially enhancing recombinant protein quality, productivity, and biological activity.
T6 745-928 Sentence denotes Metabolic engineering of animal cell expression hosts promises to address this challenge by substantially enhancing recombinant protein quality, productivity, and biological activity.
TextSentencer_T7 929-1071 Sentence denotes In this report, we describe a novel approach to metabolic engineering in Chinese hamster ovary cells by control of endogenous gene expression.
T7 929-1071 Sentence denotes In this report, we describe a novel approach to metabolic engineering in Chinese hamster ovary cells by control of endogenous gene expression.
T7 929-1071 Sentence denotes In this report, we describe a novel approach to metabolic engineering in Chinese hamster ovary cells by control of endogenous gene expression.
TextSentencer_T8 1072-1273 Sentence denotes Analysis of the advantages and limitations of using antisense DNA and gene targeting as a means of control are discussed and several gene candidates for regulation with these techniques are identified.
T8 1072-1273 Sentence denotes Analysis of the advantages and limitations of using antisense DNA and gene targeting as a means of control are discussed and several gene candidates for regulation with these techniques are identified.
T8 1072-1273 Sentence denotes Analysis of the advantages and limitations of using antisense DNA and gene targeting as a means of control are discussed and several gene candidates for regulation with these techniques are identified.
TextSentencer_T9 1274-1480 Sentence denotes Practical considerations for using these technologies to reduce the levels of the CHO cell sialidase (Warner et al., Glycobiology, 3, 455-463, 1993) as a model gene system for regulation are also presented.
T9 1274-1480 Sentence denotes Practical considerations for using these technologies to reduce the levels of the CHO cell sialidase (Warner et al., Glycobiology, 3, 455-463, 1993) as a model gene system for regulation are also presented.
T9 1274-1480 Sentence denotes Practical considerations for using these technologies to reduce the levels of the CHO cell sialidase (Warner et al., Glycobiology, 3, 455-463, 1993) as a model gene system for regulation are also presented.