> top > projects > sentences > docs > PubMed:10383126 > annotations
sentences Home  

PubMed:10383126 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-111 Sentence denotes Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay.
T1 0-111 Sentence denotes Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay.
TextSentencer_T2 112-277 Sentence denotes MYC gene overexpression was identified recently as a downstream step at the end of the Wnt/APC/beta-catenin pathway dysregulation observed in colorectal cancer (T-C.
T2 112-277 Sentence denotes MYC gene overexpression was identified recently as a downstream step at the end of the Wnt/APC/beta-catenin pathway dysregulation observed in colorectal cancer (T-C.
TextSentencer_T3 278-318 Sentence denotes He et al., Science (Washington DC), 281:
T3 278-318 Sentence denotes He et al., Science (Washington DC), 281:
TextSentencer_T4 319-336 Sentence denotes 1509-1512, 1998).
T4 319-336 Sentence denotes 1509-1512, 1998).
TextSentencer_T5 337-424 Sentence denotes It thus appears that an excess of c-myc protein is a primary cause of numerous cancers.
T5 337-424 Sentence denotes It thus appears that an excess of c-myc protein is a primary cause of numerous cancers.
TextSentencer_T6 425-568 Sentence denotes In breast cancer, MYC has been studied mostly at the DNA level because of the poor quality of available antibodies against the protein product.
T6 425-568 Sentence denotes In breast cancer, MYC has been studied mostly at the DNA level because of the poor quality of available antibodies against the protein product.
TextSentencer_T7 569-689 Sentence denotes The renewed interest in MYC calls for a sensitive and accurate method for analyzing MYC overexpression in breast tumors.
T7 569-689 Sentence denotes The renewed interest in MYC calls for a sensitive and accurate method for analyzing MYC overexpression in breast tumors.
TextSentencer_T8 690-843 Sentence denotes We have developed a real-time quantitative reverse transcription-PCR assay based on TaqMan fluorescence methodology to quantify the MYC mRNA copy number.
T8 690-843 Sentence denotes We have developed a real-time quantitative reverse transcription-PCR assay based on TaqMan fluorescence methodology to quantify the MYC mRNA copy number.
TextSentencer_T9 844-903 Sentence denotes We validated the method on a large series of breast tumors.
T9 844-903 Sentence denotes We validated the method on a large series of breast tumors.
TextSentencer_T10 904-1043 Sentence denotes MYC gene overexpression was observed in 29 of 134 (22%) breast tumor RNAs, ranging from 3.2 to 19 times the level in normal breast tissues.
T10 904-1043 Sentence denotes MYC gene overexpression was observed in 29 of 134 (22%) breast tumor RNAs, ranging from 3.2 to 19 times the level in normal breast tissues.
TextSentencer_T11 1044-1209 Sentence denotes These data imply that dysregulated MYC gene expression is potentially involved in the pathogenesis of breast cancer, especially by favoring local cell proliferation.
T11 1044-1209 Sentence denotes These data imply that dysregulated MYC gene expression is potentially involved in the pathogenesis of breast cancer, especially by favoring local cell proliferation.
TextSentencer_T12 1210-1322 Sentence denotes We also found that MYC gene overexpression was rarely due to an increased MYC gene copy number in breast cancer.
T12 1210-1322 Sentence denotes We also found that MYC gene overexpression was rarely due to an increased MYC gene copy number in breast cancer.
TextSentencer_T13 1323-1569 Sentence denotes This new, simple, rapid, and semiautomated method will be useful for screening cancer patients for MYC overexpression and will prove a powerful tool in large, randomized, prospective, cooperative group trials and in the MYC-based therapy project.
T13 1323-1569 Sentence denotes This new, simple, rapid, and semiautomated method will be useful for screening cancer patients for MYC overexpression and will prove a powerful tool in large, randomized, prospective, cooperative group trials and in the MYC-based therapy project.