> top > projects > sentences > docs > PubMed:10362840 > annotations

PubMed:10362840 JSONTXT 50 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-95 Sentence denotes Structural features in heparin that interact with VEGF165 and modulate its biological activity.
T1 0-95 Sentence denotes Structural features in heparin that interact with VEGF165 and modulate its biological activity.
T1 0-95 Sentence denotes Structural features in heparin that interact with VEGF165 and modulate its biological activity.
TextSentencer_T2 96-258 Sentence denotes The 165 amino acid form of vascular endothelial growth factor (VEGF165) is a heparin-binding growth factor with mitogenic activity for vascular endothelial cells.
T2 96-258 Sentence denotes The 165 amino acid form of vascular endothelial growth factor (VEGF165) is a heparin-binding growth factor with mitogenic activity for vascular endothelial cells.
T2 96-258 Sentence denotes The 165 amino acid form of vascular endothelial growth factor (VEGF165) is a heparin-binding growth factor with mitogenic activity for vascular endothelial cells.
TextSentencer_T3 259-466 Sentence denotes We examined activities of various heparin derivatives toward their interactions with VEGF165 using an enzyme-linked immunosorbent assay and elucidated the structural features in heparin for the interactions.
T3 259-466 Sentence denotes We examined activities of various heparin derivatives toward their interactions with VEGF165 using an enzyme-linked immunosorbent assay and elucidated the structural features in heparin for the interactions.
T3 259-466 Sentence denotes We examined activities of various heparin derivatives toward their interactions with VEGF165 using an enzyme-linked immunosorbent assay and elucidated the structural features in heparin for the interactions.
TextSentencer_T4 467-610 Sentence denotes Native heparin interacted with VEGF165, whereas N-desulfated, N-acetylated (N-DS, N-Ac-) heparin, and 6-O-desulfated (6-O-DS-) heparin did not.
T4 467-610 Sentence denotes Native heparin interacted with VEGF165, whereas N-desulfated, N-acetylated (N-DS, N-Ac-) heparin, and 6-O-desulfated (6-O-DS-) heparin did not.
T4 467-610 Sentence denotes Native heparin interacted with VEGF165, whereas N-desulfated, N-acetylated (N-DS, N-Ac-) heparin, and 6-O-desulfated (6-O-DS-) heparin did not.
TextSentencer_T5 611-702 Sentence denotes The 2-O-desulfated (2-O-DS-) heparin retained the ability for the interaction with VEGF165.
T5 611-702 Sentence denotes The 2-O-desulfated (2-O-DS-) heparin retained the ability for the interaction with VEGF165.
T5 611-702 Sentence denotes The 2-O-desulfated (2-O-DS-) heparin retained the ability for the interaction with VEGF165.
TextSentencer_T6 703-795 Sentence denotes In contrast, the 2-O-DS-heparin exhibited no ability for the interaction with FGF-2 and HGF.
T6 703-795 Sentence denotes In contrast, the 2-O-DS-heparin exhibited no ability for the interaction with FGF-2 and HGF.
T6 703-795 Sentence denotes In contrast, the 2-O-DS-heparin exhibited no ability for the interaction with FGF-2 and HGF.
TextSentencer_T7 796-973 Sentence denotes Thus, structural requirements in heparin for the specific interaction with VEGF165 are distinct from those with FGF-2 and HGF which require a high content of 2-O-sulfate groups.
T7 796-973 Sentence denotes Thus, structural requirements in heparin for the specific interaction with VEGF165 are distinct from those with FGF-2 and HGF which require a high content of 2-O-sulfate groups.
T7 796-973 Sentence denotes Thus, structural requirements in heparin for the specific interaction with VEGF165 are distinct from those with FGF-2 and HGF which require a high content of 2-O-sulfate groups.
TextSentencer_T8 974-1300 Sentence denotes In a cell proliferation assay, native heparin and 2-O-DS-heparin exhibited inhibitory abilities for VEGF165-induced proliferation of human umbilical vein endothelial cells (HUVECs) with their high concentrations (more than 64 microg/ml), while only native heparin could enhance the proliferation of the chlorate-treated cells.
T8 974-1300 Sentence denotes In a cell proliferation assay, native heparin and 2-O-DS-heparin exhibited inhibitory abilities for VEGF165-induced proliferation of human umbilical vein endothelial cells (HUVECs) with their high concentrations (more than 64 microg/ml), while only native heparin could enhance the proliferation of the chlorate-treated cells.
T8 974-1300 Sentence denotes In a cell proliferation assay, native heparin and 2-O-DS-heparin exhibited inhibitory abilities for VEGF165-induced proliferation of human umbilical vein endothelial cells (HUVECs) with their high concentrations (more than 64 microg/ml), while only native heparin could enhance the proliferation of the chlorate-treated cells.
TextSentencer_T9 1301-1504 Sentence denotes These results suggested that a high content of 2-O-sulfate groups is not required for the specific interaction with VEGF165alone, although it is essential for the mitogenic activity of the growth factor.
T9 1301-1504 Sentence denotes These results suggested that a high content of 2-O-sulfate groups is not required for the specific interaction with VEGF165alone, although it is essential for the mitogenic activity of the growth factor.
T9 1301-1504 Sentence denotes These results suggested that a high content of 2-O-sulfate groups is not required for the specific interaction with VEGF165alone, although it is essential for the mitogenic activity of the growth factor.