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PubMed:10336988 JSONTXT 72 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-196 Sentence denotes Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus.
T1 0-196 Sentence denotes Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus.
TextSentencer_T2 197-337 Sentence denotes Sialic acid, as a terminal saccharide residue on cell surface glycoconjugates, plays an important role in a variety of biological processes.
T2 197-337 Sentence denotes Sialic acid, as a terminal saccharide residue on cell surface glycoconjugates, plays an important role in a variety of biological processes.
TextSentencer_T3 338-549 Sentence denotes In this study, we investigated subclones of the human B lymphoma cell line BJA-B for differences in the glycosylation of cell surface glycoconjugates, and studied the functional implications of such differences.
T3 338-549 Sentence denotes In this study, we investigated subclones of the human B lymphoma cell line BJA-B for differences in the glycosylation of cell surface glycoconjugates, and studied the functional implications of such differences.
TextSentencer_T4 550-771 Sentence denotes With respect to the expression level of most of the tested B cell-associated antigens, as well as the presence of penultimate saccharide moieties on oligosaccharide chains, subclones were phenotypically indistinguishable.
T4 550-771 Sentence denotes With respect to the expression level of most of the tested B cell-associated antigens, as well as the presence of penultimate saccharide moieties on oligosaccharide chains, subclones were phenotypically indistinguishable.
TextSentencer_T5 772-947 Sentence denotes Marked differences among subclones, however, were found in the overall level of glycoconjugate sialylation, involving both alpha-2,6 and alpha-2,3-linked sialic acid residues.
T5 772-947 Sentence denotes Marked differences among subclones, however, were found in the overall level of glycoconjugate sialylation, involving both alpha-2,6 and alpha-2,3-linked sialic acid residues.
TextSentencer_T6 948-1037 Sentence denotes Accordingly, subclones were classified as highly- (group I) or hyposialylated (group II).
T6 948-1037 Sentence denotes Accordingly, subclones were classified as highly- (group I) or hyposialylated (group II).
TextSentencer_T7 1038-1169 Sentence denotes The function of two sialic acid-dependent receptor-mediated processes is correlated with the sialylation status of BJA-B subclones.
T7 1038-1169 Sentence denotes The function of two sialic acid-dependent receptor-mediated processes is correlated with the sialylation status of BJA-B subclones.
TextSentencer_T8 1170-1432 Sentence denotes Susceptibility to and binding of the B lymphotropic papovavirus (LPV) was dependent on a high sialylation status of host cells, suggesting that differential sialylation in BJA-B cells can modulate LPV infection via its alpha-2,6-sialylated glycoprotein receptor.
T8 1170-1432 Sentence denotes Susceptibility to and binding of the B lymphotropic papovavirus (LPV) was dependent on a high sialylation status of host cells, suggesting that differential sialylation in BJA-B cells can modulate LPV infection via its alpha-2,6-sialylated glycoprotein receptor.
TextSentencer_T9 1433-1602 Sentence denotes CD95-mediated apoptosis, induced by either the human CD95 ligand or a cytotoxic anti-CD95 monoclonal antibody, was drastically enhanced in hyposialylated group II cells.
T9 1433-1602 Sentence denotes CD95-mediated apoptosis, induced by either the human CD95 ligand or a cytotoxic anti-CD95 monoclonal antibody, was drastically enhanced in hyposialylated group II cells.
TextSentencer_T10 1603-1732 Sentence denotes An increase in endogenous sialylation may be one antiapoptotic mechanism that converts tumor cells to a more malignant phenotype.
T10 1603-1732 Sentence denotes An increase in endogenous sialylation may be one antiapoptotic mechanism that converts tumor cells to a more malignant phenotype.
TextSentencer_T11 1733-1910 Sentence denotes To our knowledge, this is the first report demonstrating that differential sialylation in a clonal cell line may regulate the function of virus and signal-transducing receptors.
T11 1733-1910 Sentence denotes To our knowledge, this is the first report demonstrating that differential sialylation in a clonal cell line may regulate the function of virus and signal-transducing receptors.