| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-123 |
Sentence |
denotes |
Characterization of a novel type of serine/threonine kinase that specifically phosphorylates the human goodpasture antigen. |
| T2 |
124-207 |
Sentence |
denotes |
Goodpasture disease is an autoimmune disorder that occurs naturally only in humans. |
| T3 |
208-333 |
Sentence |
denotes |
Also exclusive to humans is the phosphorylation process that targets the unique N-terminal region of the Goodpasture antigen. |
| T4 |
334-463 |
Sentence |
denotes |
Here we report the molecular cloning of GPBP (Goodpasture antigen-binding protein), a previously unknown 624-residue polypeptide. |
| T5 |
464-716 |
Sentence |
denotes |
Although the predicted sequence does not meet the conventional structural requirements for a protein kinase, its recombinant counterpart specifically binds to and phosphorylates the exclusive N-terminal region of the human Goodpasture antigen in vitro. |
| T6 |
717-885 |
Sentence |
denotes |
This novel kinase is widely expressed in human tissues but shows preferential expression in the histological structures that are targets of common autoimmune responses. |
| T7 |
886-981 |
Sentence |
denotes |
The work presented in this report highlights a novel gene to be explored in human autoimmunity. |
