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PubMed:10196694 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-225 Sentence denotes An Asn > Lys substitution in saposin B involving a conserved amino acidic residue and leading to the loss of the single N-glycosylation site in a patient with metachromatic leukodystrophy and normal arylsulphatase A activity.
T1 0-225 Sentence denotes An Asn > Lys substitution in saposin B involving a conserved amino acidic residue and leading to the loss of the single N-glycosylation site in a patient with metachromatic leukodystrophy and normal arylsulphatase A activity.
TextSentencer_T2 226-361 Sentence denotes Sphingolipid activator proteins are small glycoproteins required for the degradation of sphingolipids by specific lysosomal hydrolases.
T2 226-361 Sentence denotes Sphingolipid activator proteins are small glycoproteins required for the degradation of sphingolipids by specific lysosomal hydrolases.
TextSentencer_T3 362-537 Sentence denotes Four of them, called saposins, are encoded by the prosaposin gene, the product of which is proteolytically cleaved into the four mature saposin proteins (saposins A, B, C, D).
T3 362-537 Sentence denotes Four of them, called saposins, are encoded by the prosaposin gene, the product of which is proteolytically cleaved into the four mature saposin proteins (saposins A, B, C, D).
TextSentencer_T4 538-686 Sentence denotes One of these, saposin B, is necessary in the hydrolysis of sulphatide by arylsulphatase A where it presents the solubilised substrate to the enzyme.
T4 538-686 Sentence denotes One of these, saposin B, is necessary in the hydrolysis of sulphatide by arylsulphatase A where it presents the solubilised substrate to the enzyme.
TextSentencer_T5 687-797 Sentence denotes As an alternative to arylsulphatase A deficiency, deficiency of saposin B causes metachromatic leukodystrophy.
T5 687-797 Sentence denotes As an alternative to arylsulphatase A deficiency, deficiency of saposin B causes metachromatic leukodystrophy.
TextSentencer_T6 798-999 Sentence denotes We identified a previously undescribed mutation (N215K) in the prosaposin gene of a patient with metachromatic leukodystrophy but with normal arylsulphatase A activity and elevated sulphatide in urine.
T6 798-999 Sentence denotes We identified a previously undescribed mutation (N215K) in the prosaposin gene of a patient with metachromatic leukodystrophy but with normal arylsulphatase A activity and elevated sulphatide in urine.
TextSentencer_T7 1000-1119 Sentence denotes The mutation involves a highly conserved amino acidic residue and abolishes the only N-glycosylation site of saposin B.
T7 1000-1119 Sentence denotes The mutation involves a highly conserved amino acidic residue and abolishes the only N-glycosylation site of saposin B.