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PubMed:10082254 JSONTXT 7 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-96 Sentence denotes Serum melatonin kinetics and long-term melatonin treatment for sleep disorders in Rett syndrome.
T1 0-96 Sentence denotes Serum melatonin kinetics and long-term melatonin treatment for sleep disorders in Rett syndrome.
TextSentencer_T2 97-329 Sentence denotes We studied the circadian rhythm of serum melatonin levels in two patients with classical Rett syndrome having severe sleep disorders; serum melatonin levels were measured before and during melatonin treatment using radioimmunoassay.
T2 97-329 Sentence denotes We studied the circadian rhythm of serum melatonin levels in two patients with classical Rett syndrome having severe sleep disorders; serum melatonin levels were measured before and during melatonin treatment using radioimmunoassay.
TextSentencer_T3 330-406 Sentence denotes Patient 1 had a free-running rhythm of sleep-wake cycle from 3 years of age.
T3 330-406 Sentence denotes Patient 1 had a free-running rhythm of sleep-wake cycle from 3 years of age.
TextSentencer_T4 407-542 Sentence denotes At the age of 4 years, the peak time of melatonin was delayed 6 h compared to normal control and the peak value was at the lower limit.
T4 407-542 Sentence denotes At the age of 4 years, the peak time of melatonin was delayed 6 h compared to normal control and the peak value was at the lower limit.
TextSentencer_T5 543-647 Sentence denotes Patient 2 had a fragmented sleep pattern accompanied by night screaming from 1 year and 6 months of age.
T5 543-647 Sentence denotes Patient 2 had a fragmented sleep pattern accompanied by night screaming from 1 year and 6 months of age.
TextSentencer_T6 648-762 Sentence denotes At the age of 10 years, the peak time of melatonin secretion was normal but the peak value was at the lower limit.
T6 648-762 Sentence denotes At the age of 10 years, the peak time of melatonin secretion was normal but the peak value was at the lower limit.
TextSentencer_T7 763-828 Sentence denotes These patients were given 5 mg melatonin orally prior to bedtime.
T7 763-828 Sentence denotes These patients were given 5 mg melatonin orally prior to bedtime.
TextSentencer_T8 829-905 Sentence denotes Exogenous melatonin dramatically improved the sleep-wake cycle in patient 1.
T8 829-905 Sentence denotes Exogenous melatonin dramatically improved the sleep-wake cycle in patient 1.
TextSentencer_T9 906-1016 Sentence denotes In patient 2, exogenous melatonin showed a hypnotic effect but early morning awakenings occurred occasionally.
T9 906-1016 Sentence denotes In patient 2, exogenous melatonin showed a hypnotic effect but early morning awakenings occurred occasionally.
TextSentencer_T10 1017-1155 Sentence denotes When melatonin treatment was stopped, the sleep disorders recurred and re-administration of 3 mg melatonin was effective in both patients.
T10 1017-1155 Sentence denotes When melatonin treatment was stopped, the sleep disorders recurred and re-administration of 3 mg melatonin was effective in both patients.
TextSentencer_T11 1156-1223 Sentence denotes The effect was maintained over 2 years without any adverse effects.
T11 1156-1223 Sentence denotes The effect was maintained over 2 years without any adverse effects.
TextSentencer_T12 1224-1351 Sentence denotes These findings suggests that sleep disorders in patients with Rett syndrome may relate with an impaired secretion of melatonin.
T12 1224-1351 Sentence denotes These findings suggests that sleep disorders in patients with Rett syndrome may relate with an impaired secretion of melatonin.