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PubMed:10024662 JSONTXT 51 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-166 Sentence denotes The Saccharomyces cerevisiae CWH8 gene is required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum and for efficient N-glycosylation.
T1 0-166 Sentence denotes The Saccharomyces cerevisiae CWH8 gene is required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum and for efficient N-glycosylation.
T1 0-166 Sentence denotes The Saccharomyces cerevisiae CWH8 gene is required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum and for efficient N-glycosylation.
TextSentencer_T2 167-260 Sentence denotes The Saccharomyces cerevisiae mutant cwh8 was previously found to have an anomalous cell wall.
T2 167-260 Sentence denotes The Saccharomyces cerevisiae mutant cwh8 was previously found to have an anomalous cell wall.
T2 167-260 Sentence denotes The Saccharomyces cerevisiae mutant cwh8 was previously found to have an anomalous cell wall.
TextSentencer_T3 261-326 Sentence denotes Here we show that the cwh8 mutant has an N -glycosylation defect.
T3 261-326 Sentence denotes Here we show that the cwh8 mutant has an N -glycosylation defect.
T3 261-326 Sentence denotes Here we show that the cwh8 mutant has an N -glycosylation defect.
TextSentencer_T4 327-505 Sentence denotes We found that cwh8 cells were resistant to vanadate and sensitive to hygromycin B, and produced glycoforms of invertase and carboxypeptidase Y with a reduced number of N -chains.
T4 327-505 Sentence denotes We found that cwh8 cells were resistant to vanadate and sensitive to hygromycin B, and produced glycoforms of invertase and carboxypeptidase Y with a reduced number of N -chains.
T4 327-505 Sentence denotes We found that cwh8 cells were resistant to vanadate and sensitive to hygromycin B, and produced glycoforms of invertase and carboxypeptidase Y with a reduced number of N -chains.
TextSentencer_T5 506-535 Sentence denotes We have cloned the CWH8 gene.
T5 506-535 Sentence denotes We have cloned the CWH8 gene.
T5 506-535 Sentence denotes We have cloned the CWH8 gene.
TextSentencer_T6 536-634 Sentence denotes We found that it was nonessential and encoded a putative transmembrane protein of 239 amino acids.
T6 536-634 Sentence denotes We found that it was nonessential and encoded a putative transmembrane protein of 239 amino acids.
T6 536-634 Sentence denotes We found that it was nonessential and encoded a putative transmembrane protein of 239 amino acids.
TextSentencer_T7 635-1047 Sentence denotes Comparison of the in vitro oligosaccharyl transferase activities of membrane preparations from wild type or cwh8 Delta cells revealed no differences in enzyme kinetic properties indicating that the oligosaccharyl transferase complex of mutant cells was not affected. cwh8 Delta cells also produced normal dolichols and dolichol-linked oligosaccharide intermediates including the full-length form Glc3Man9GlcNAc2.
T7 635-1047 Sentence denotes Comparison of the in vitro oligosaccharyl transferase activities of membrane preparations from wild type or cwh8 Delta cells revealed no differences in enzyme kinetic properties indicating that the oligosaccharyl transferase complex of mutant cells was not affected. cwh8 Delta cells also produced normal dolichols and dolichol-linked oligosaccharide intermediates including the full-length form Glc3Man9GlcNAc2.
T7 635-1047 Sentence denotes Comparison of the in vitro oligosaccharyl transferase activities of membrane preparations from wild type or cwh8 Delta cells revealed no differences in enzyme kinetic properties indicating that the oligosaccharyl transferase complex of mutant cells was not affected. cwh8 Delta cells also produced normal dolichols and dolichol-linked oligosaccharide intermediates including the full-length form Glc3Man9GlcNAc2.
TextSentencer_T8 1048-1166 Sentence denotes The level of dolichol-linked oligosaccharides in cwh8 Delta cells was, however, reduced to about 20% of the wild type.
T8 1048-1166 Sentence denotes The level of dolichol-linked oligosaccharides in cwh8 Delta cells was, however, reduced to about 20% of the wild type.
T8 1048-1166 Sentence denotes The level of dolichol-linked oligosaccharides in cwh8 Delta cells was, however, reduced to about 20% of the wild type.
TextSentencer_T9 1167-1335 Sentence denotes We propose that inefficient N -glycosylation of secretory proteins in cwh8 Delta cells is caused by an insufficient supply of dolichol-linked oligosaccharide substrate.
T9 1167-1335 Sentence denotes We propose that inefficient N -glycosylation of secretory proteins in cwh8 Delta cells is caused by an insufficient supply of dolichol-linked oligosaccharide substrate.
T9 1167-1335 Sentence denotes We propose that inefficient N -glycosylation of secretory proteins in cwh8 Delta cells is caused by an insufficient supply of dolichol-linked oligosaccharide substrate.