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PMC:3586680 / 5001-6633 JSONTXT 23 Projects

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Id Subject Object Predicate Lexical cue
T898 0-151 Sentence denotes Reversal of TMZ resistance may be achieved by MGMT pseudosubstrates, O6-benzylguanine and lomeguatrib to sensitize tumors to TMZ (Zhang et al., 2012b).
T34 0-151 Sentence denotes Reversal of TMZ resistance may be achieved by MGMT pseudosubstrates, O6-benzylguanine and lomeguatrib to sensitize tumors to TMZ (Zhang et al., 2012b).
T899 152-357 Sentence denotes Methoxyamine-blocker of base excision repair contributes significantly to TMZ cytotoxicity particularly when O6-methylguanine adducts are repaired or tolerated (Goellner et al., 2011; Zhang et al., 2012b).
T35 152-357 Sentence denotes Methoxyamine-blocker of base excision repair contributes significantly to TMZ cytotoxicity particularly when O6-methylguanine adducts are repaired or tolerated (Goellner et al., 2011; Zhang et al., 2012b).
T900 358-517 Sentence denotes Dual targeting of base excision repair and NAD(+) biosynthesis may reverse TMZ resistance in patients with resistant and recurrent GBM (Goellner et al., 2011).
T36 358-517 Sentence denotes Dual targeting of base excision repair and NAD(+) biosynthesis may reverse TMZ resistance in patients with resistant and recurrent GBM (Goellner et al., 2011).
T901 518-702 Sentence denotes Interferon-β (IFN-β), levetiracetam (LEV), resveratrol, and valproic acid (VAP) increase the sensitivity of TMZ through MGMT-dependent or -independent mechanisms (Nakada et al., 2012).
T37 518-702 Sentence denotes Interferon-β (IFN-β), levetiracetam (LEV), resveratrol, and valproic acid (VAP) increase the sensitivity of TMZ through MGMT-dependent or -independent mechanisms (Nakada et al., 2012).
T902 703-816 Sentence denotes Resveratrol, a natural polyphenol, reverses TMZ resistance via an NF-κB-dependent mechanism (Huang et al., 2012).
T38 703-816 Sentence denotes Resveratrol, a natural polyphenol, reverses TMZ resistance via an NF-κB-dependent mechanism (Huang et al., 2012).
T903 817-928 Sentence denotes STAT3 inhibitor or STAT3 knockdown potentiates TMZ efficacy in resistant GBM cell lines (Kohsaka et al., 2012).
T39 817-928 Sentence denotes STAT3 inhibitor or STAT3 knockdown potentiates TMZ efficacy in resistant GBM cell lines (Kohsaka et al., 2012).
T904 929-1029 Sentence denotes Intratumoral hypoxia is common in GBMs and may be associated with the development of TMZ resistance.
T40 929-1029 Sentence denotes Intratumoral hypoxia is common in GBMs and may be associated with the development of TMZ resistance.
T905 1030-1117 Sentence denotes Induced hyperoxia can be utilized to reverse TMZ resistance in GBMs (Sun et al., 2012).
T41 1030-1117 Sentence denotes Induced hyperoxia can be utilized to reverse TMZ resistance in GBMs (Sun et al., 2012).
T906 1118-1185 Sentence denotes Cancer stem cells are probably the key to failure in TMZ treatment.
T42 1118-1185 Sentence denotes Cancer stem cells are probably the key to failure in TMZ treatment.
T907 1186-1374 Sentence denotes The concept of cancer stem cell survival from treatment with TMZ and other chemotherapeutic drugs has been more complicated than previously thought (Beier et al., 2011; Chen et al., 2012).
T43 1186-1374 Sentence denotes The concept of cancer stem cell survival from treatment with TMZ and other chemotherapeutic drugs has been more complicated than previously thought (Beier et al., 2011; Chen et al., 2012).
T908 1375-1501 Sentence denotes CD133-positive cancer stem cells are expressed in both normal stem cells and cancer stem cells (Donovan and Pilkington, 2012).
T44 1375-1501 Sentence denotes CD133-positive cancer stem cells are expressed in both normal stem cells and cancer stem cells (Donovan and Pilkington, 2012).
T909 1502-1632 Sentence denotes However, the role of CD133 as a marker for glioma cancer stem cells relative to its biological function has yet to be established.
T45 1502-1632 Sentence denotes However, the role of CD133 as a marker for glioma cancer stem cells relative to its biological function has yet to be established.