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PMC:3586680 / 17677-18672 JSONTXT 24 Projects

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Id Subject Object Predicate Lexical cue
T9743 0-63 Sentence denotes Whether WWOX affects TMZ sensitivity has never been determined.
T124 0-63 Sentence denotes Whether WWOX affects TMZ sensitivity has never been determined.
T9744 64-165 Sentence denotes Binding proteins for WWOX and/or p53 are likely to affect apoptosis and TMZ sensitivity in GBM cells.
T125 64-165 Sentence denotes Binding proteins for WWOX and/or p53 are likely to affect apoptosis and TMZ sensitivity in GBM cells.
T9745 166-281 Sentence denotes WWOX binds MEK, and that PMA dissociates this complex for causing apoptosis of T leukemia cells (Lin et al., 2011).
T126 166-281 Sentence denotes WWOX binds MEK, and that PMA dissociates this complex for causing apoptosis of T leukemia cells (Lin et al., 2011).
T9746 282-388 Sentence denotes Thus, appropriate chemicals, which break apart the WWOX/MEK complex, are expected to cause GBM cell death.
T127 282-388 Sentence denotes Thus, appropriate chemicals, which break apart the WWOX/MEK complex, are expected to cause GBM cell death.
T9747 389-556 Sentence denotes Preliminary studies from our screening of chemicals have selected certain small molecules that induce apoptosis of many types of cancer cells (Lu et al., unpublished).
T128 389-556 Sentence denotes Preliminary studies from our screening of chemicals have selected certain small molecules that induce apoptosis of many types of cancer cells (Lu et al., unpublished).
T9748 557-674 Sentence denotes Indeed, specific inhibition of MEK by selumetinib enhances TMZ-induced cancer cell death in vivo (Holt et al., 2012).
T129 557-674 Sentence denotes Indeed, specific inhibition of MEK by selumetinib enhances TMZ-induced cancer cell death in vivo (Holt et al., 2012).
T9749 675-732 Sentence denotes Serum factors can be utilized for blocking cancer growth.
T130 675-732 Sentence denotes Serum factors can be utilized for blocking cancer growth.
T9750 733-930 Sentence denotes For example, serum complement C1q induces apoptosis of prostate cancer and neuroblastomas cells without participation of downstream proteins in the classical activation pathway (Hong et al., 2009).
T131 733-930 Sentence denotes For example, serum complement C1q induces apoptosis of prostate cancer and neuroblastomas cells without participation of downstream proteins in the classical activation pathway (Hong et al., 2009).
T9751 931-995 Sentence denotes In this event, ectopic WWOX is activated for inducing apoptosis.
T132 931-995 Sentence denotes In this event, ectopic WWOX is activated for inducing apoptosis.