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PMC:3312845 / 6715-8147 JSONTXT 23 Projects

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Id Subject Object Predicate Lexical cue
T3276 0-37 Sentence denotes Intracerebroventricular drug infusion
T54 0-37 Sentence denotes Intracerebroventricular drug infusion
T3277 38-196 Sentence denotes Rats were divided into two groups: vehicle (saline)-treated and soluble TNFp55 receptor (sTNFp55R, 50 μg/ml; Sigma-Aldrich Co., St. Louis, MO)-treated groups.
T55 38-196 Sentence denotes Rats were divided into two groups: vehicle (saline)-treated and soluble TNFp55 receptor (sTNFp55R, 50 μg/ml; Sigma-Aldrich Co., St. Louis, MO)-treated groups.
T3278 197-356 Sentence denotes The dosage of sTNFp55R was determined as the highest dose that induced SE of comparable severity in 100% of animals with 5% mortality in the preliminary study.
T56 197-356 Sentence denotes The dosage of sTNFp55R was determined as the highest dose that induced SE of comparable severity in 100% of animals with 5% mortality in the preliminary study.
T3279 357-474 Sentence denotes Animals were anesthetized (Zolretil, 50 mg/kg, i.m.; Virbac Laboratories, France) and placed in a stereotaxic frames.
T57 357-474 Sentence denotes Animals were anesthetized (Zolretil, 50 mg/kg, i.m.; Virbac Laboratories, France) and placed in a stereotaxic frames.
T3280 475-785 Sentence denotes For the osmotic pump implantation, holes were drilled through the skull to introduce a brain infusion kit 1 (Alzet, Cupertino, CA) into the right lateral ventricle (1 mm posterior; 1.5 mm lateral; - 3.5 mm depth; flat skull position with bregma as reference), according to the atlas of Paxinos and Watson [24].
T58 475-785 Sentence denotes For the osmotic pump implantation, holes were drilled through the skull to introduce a brain infusion kit 1 (Alzet, Cupertino, CA) into the right lateral ventricle (1 mm posterior; 1.5 mm lateral; - 3.5 mm depth; flat skull position with bregma as reference), according to the atlas of Paxinos and Watson [24].
T3281 786-896 Sentence denotes The infusion kit was sealed with dental cement and connected to an osmotic pump (1007D, Alzet, Cupertino, CA).
T59 786-896 Sentence denotes The infusion kit was sealed with dental cement and connected to an osmotic pump (1007D, Alzet, Cupertino, CA).
T3282 897-963 Sentence denotes The pump was placed in a subcutaneous pocket in the dorsal region.
T60 897-963 Sentence denotes The pump was placed in a subcutaneous pocket in the dorsal region.
T3283 964-1025 Sentence denotes Animals received 0.5 μl/hr of vehicle or compound for 1 week.
T61 964-1025 Sentence denotes Animals received 0.5 μl/hr of vehicle or compound for 1 week.
T3284 1026-1089 Sentence denotes Therefore, the dose of sTNFp55R was 0.6 μg/day per each animal.
T62 1026-1089 Sentence denotes Therefore, the dose of sTNFp55R was 0.6 μg/day per each animal.
T3285 1090-1150 Sentence denotes The compounds began to be immediately infused after surgery.
T63 1090-1150 Sentence denotes The compounds began to be immediately infused after surgery.
T3286 1151-1274 Sentence denotes Since the volume of vasogenic edema peaked at 2-3 days after SE in our previous studies [5-8,20], we chose this time point.
T64 1151-1274 Sentence denotes Since the volume of vasogenic edema peaked at 2-3 days after SE in our previous studies [5-8,20], we chose this time point.
T3287 1275-1432 Sentence denotes Thus, our experimental schedules at least inhibit the function of TNF-α from 3 days prior to SE to 4 days after SE when the volume of vasogenic edema peaked.
T65 1275-1432 Sentence denotes Thus, our experimental schedules at least inhibit the function of TNF-α from 3 days prior to SE to 4 days after SE when the volume of vasogenic edema peaked.