Id |
Subject |
Object |
Predicate |
Lexical cue |
S1 |
0-97 |
Sentence |
denotes |
Selection of down-regulated sequences along the monocytic differentiation of leukemic HL60 cells. |
S2 |
98-286 |
Sentence |
denotes |
In order to dissect the molecular mechanisms of monocytic differentiation we have developed a subtractive hybridisation method based on a simplified 'representational difference analysis'. |
S3 |
287-415 |
Sentence |
denotes |
We have selected 16 sequences and confirmed their down-regulation along the TPA-induced monocytic differentiation of HL60 cells. |
S4 |
416-599 |
Sentence |
denotes |
Among these sequences we have identified the alpha-tubulin, the TaxREB protein and two ribosomal protein sequences which had not been previously described as differentially expressed. |
S5 |
600-802 |
Sentence |
denotes |
These results add to our knowledge about the molecules implicated along the monocytic differentiation and growth arrest of leukemic cells and provide a first step in the study of their respective roles. |