| Id |
Subject |
Object |
Predicate |
Lexical cue |
| S1 |
0-100 |
Sentence |
denotes |
Expression of the nucleoside diphosphate kinase in human skin cancers: an immunohistochemical study. |
| S2 |
101-289 |
Sentence |
denotes |
Expression of nucleoside diphosphate(NDP) kinase, which is homologous to the nm23 gene product in a variety of species, has been found to be inversely associated with metastatic potential. |
| S3 |
290-453 |
Sentence |
denotes |
However, the relationship remains controversial according to the tumor cell types and experimental system, with conflicting results from different research groups. |
| S4 |
454-748 |
Sentence |
denotes |
In order to determine whether NDP kinase expression serves as a marker for metastatic potential in human skin cancer, we assessed the levels of NDP kinase expression in 9 keratoacanthomas (KAs), 26 squamous cell carcinomas (SCCs), and 25 basal cell carcinomas (BCCs) using immunohistochemistry. |
| S5 |
749-822 |
Sentence |
denotes |
The expression of NDP kinase was intense in KA and SCC compared with BCC. |
| S6 |
823-925 |
Sentence |
denotes |
However, the difference of NDP kinase expression between KA and SCC was not statistically significant. |
| S7 |
926-1060 |
Sentence |
denotes |
And there was no statistically significant difference in NDP kinase expression between SCC with metastasis and SCC without metastasis. |
| S8 |
1061-1194 |
Sentence |
denotes |
Our results contradict the hypothesis concerning the possible role of nm23 gene as a metastatic suppressor gene in human skin cancer. |
| S9 |
1195-1339 |
Sentence |
denotes |
The mechanism of overexpression in various tumor cell types and its biological significance in cutaneous carcinogenesis remain to be determined. |
