| Id |
Subject |
Object |
Predicate |
Lexical cue |
| S1 |
0-136 |
Sentence |
denotes |
A case of hypersensitivity to thyroid hormones with normally functioning thyroid gland and increased nuclear triiodothyronine receptors. |
| S2 |
137-291 |
Sentence |
denotes |
A 52-year-old male presented himself with tachycardia crises which appeared first during childhood, increased in frequency without goiter or exophthalmos. |
| S3 |
292-338 |
Sentence |
denotes |
Cardiac and adrenergic diseases were excluded. |
| S4 |
339-500 |
Sentence |
denotes |
The thyroid function was normal regarding T4, free T4 and T3, TBG, radioiodine uptake, TSH and T3 suppressibility; however the TSH response to TRH was decreased. |
| S5 |
501-742 |
Sentence |
denotes |
The lymphocyte nuclear T3 receptor was found with an affinity close to that of normal volunteers (Ka: 1.42 x 10(10) M-1 vs 1.95 +/- 0.35 x 10(10) M-1) and a binding capacity markedly increased (9.9 vs 3.7 +/- 0.4 fmol T3/100 micrograms DNA). |
| S6 |
743-876 |
Sentence |
denotes |
Pindolol was inefficient on the dysrhythmia which disappeared with carbimazole and relapsed after withdrawal of the antithyroid drug. |
| S7 |
877-986 |
Sentence |
denotes |
Under carbimazole, the plasma T4 markedly decreased (27.7 +/- 3.6 nmol/l) but the patient remained euthyroid. |
| S8 |
987-1223 |
Sentence |
denotes |
The clinical course and the laboratory data suggest that the tachycardia crises are the consequence of a hypersensitivity of the heart to thyroid hormones, associated with an increased number of T3 nuclear receptor sites in lymphocytes. |